Gene name: CGI121
Reference locus (S288C): YML036W
Gene biotype: protein_coding
Description: Component of the EKC/KEOPS complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; Cgi121p is dispensable for tRNA modification; other complex members are Bud32p, Kae1p, Pcc1p, and Gon7p; Belongs to the CGI121/TPRKB family
Top 10 interactors (score): BUD32 (0.999); KAE1 (0.999); GON7 (0.999); PCC1 (0.99); QRI7 (0.984); SUA5 (0.939); CDC13 (0.778); YPR170W-B (0.75); PBP2 (0.742); MAY24 (0.696); YPL109C (0.671); MCR1 (0.6); MPH1 (0.592); NOG2 (0.586); SMX2 (0.557); SEN2 (0.526); TCP1 (0.49); DCP1 (0.489); DUT1 (0.487); DOP1 (0.479)
Homologues (species, bitscore): TPRKB (Homo sapiens, 83.2); Tprkb (Mus musculus, 85.1); tprkb (Danio rerio, 81.3); tprkb (Xenopus tropicalis, 85.1); W03F8.4 (Caenorhabditis elegans, 67.8); AT4G34412 (Arabidopsis thaliana, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:255253-255905:+ | gene-YML036W_AKU4011 | rna-NM_001182394.1_AKU4011 | cds-NP_013676.2_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:286983-287634:- | gene-YML036W_BG1 | rna-NM_001182394.1_BG1 | cds-NP_013676.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:195159-195811:+ | gene-YML036W_Bruggeman | rna-NM_001182394.1_Bruggeman | cds-NP_013676.2_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:197709-198360:+ | gene-YML036W_CAT1 | rna-NM_001182394.1_CAT1 | cds-NP_013676.2_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:188208-188860:+ | gene-YML036W_CBS1585 | rna-NM_001182394.1_CBS1585 | cds-NP_013676.2_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:193724-194375:+ | gene-YML036W_CBS436 | rna-NM_001182394.1_CBS436 | cds-NP_013676.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:301941-302593:+ | gene-YML036W_CBS6412 | rna-NM_001182394.1_CBS6412 | cds-NP_013676.2_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:187460-188112:+ | gene-YML036W_CBS6413 | rna-NM_001182394.1_CBS6413 | cds-NP_013676.2_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:200164-200816:+ | gene-YML036W_CENPK1137D | rna-NM_001182394.1_CENPK1137D | cds-NP_013676.2_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:188209-188860:+ | gene-YML036W_EthanolRed | rna-NM_001182394.1_EthanolRed | cds-NP_013676.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:191173-191824:+ | gene-YML036W_FaliES1 | rna-NM_001182394.1_FaliES1 | cds-NP_013676.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000237.1:20309-20960:- | gene-YML036W_JAY291 | rna-NM_001182394.1_JAY291 | cds-NP_013676.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:192894-193546:+ | gene-YML036W_MUCL30387 | rna-NM_001182394.1_MUCL30387 | cds-NP_013676.2_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:196905-197557:+ | gene-YML036W_MUCL30388 | rna-NM_001182394.1_MUCL30388 | cds-NP_013676.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:188488-189140:+ | gene-YML036W_MUCL39482 | rna-NM_001182394.1_MUCL39482 | cds-NP_013676.2_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:193997-194648:+ | gene-YML036W_MUCL42920 | rna-NM_001182394.1_MUCL42920 | cds-NP_013676.2_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:205596-206247:+ | gene-YML036W_NCIM3186 | rna-NM_001182394.1_NCIM3186 | cds-NP_013676.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:188431-189083:+ | gene-YML036W_NCYC1407 | rna-NM_001182394.1_NCYC1407 | cds-NP_013676.2_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:194316-194967:+ | gene-YML036W_PE2H3 | rna-NM_001182394.1_PE2H3 | cds-NP_013676.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:200411-201062:+ | gene-YML036W_PE2H4 | rna-NM_001182394.1_PE2H4 | cds-NP_013676.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:205642-206293:+ | gene-YML036W_S288C | rna-NM_001182394.1_S288C | cds-NP_013676.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000088.1:32555-33206:- | gene-YML036W_SA1 | rna-NM_001182394.1_SA1 | cds-NP_013676.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:188246-188897:+ | gene-YML036W_ThermosaccDry | rna-NM_001182394.1_ThermosaccDry | cds-NP_013676.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:192257-192908:+ | gene-YML036W_VR1 | rna-NM_001182394.1_VR1 | cds-NP_013676.2_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:167322-167974:+ | gene-YML036W_ZTW1 | rna-NM_001182394.1_ZTW1 | cds-NP_013676.2_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:199066-199709:+ | gene-YML036W_Sparadoxus | rna-NM_001182394.1_Sparadoxus | cds-NP_013676.2_Sparadoxus | 89.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |