CFT2 (YLR115W)


Gene profile

Gene name: CFT2
Reference locus (S288C): YLR115W
Gene biotype: protein_coding

Description: Cleavage factor two protein 2; Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein

Top 10 interactors (score): TFC4 (0.999); MPE1 (0.999); RNA15 (0.999); RNA14 (0.999); SWD2 (0.999); SYC1 (0.999); YSH1 (0.999); PTI1 (0.999); PAP1 (0.999); PTA1 (0.999); REF2 (0.999); SSU72 (0.999); PFS2 (0.999); YTH1 (0.999); CFT1 (0.999); FIP1 (0.999); PCF11 (0.998); GLC7 (0.996); CLP1 (0.979); TAF1 (0.966)

Homologues (species, bitscore): CPSF2 (Homo sapiens, 130.6); Cpsf2 (Mus musculus, 127.1); cpsf2 (Danio rerio, 129.4); cpsf2 (Xenopus tropicalis, 128.3); Cpsf100 (Drosophila melanogaster, 134.8); cpsf-2 (Caenorhabditis elegans, 104.0); CPSF100 (Arabidopsis thaliana, 169.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:360468-363047:+ gene-YLR115W_AKU4011 rna-NM_001182002.1_AKU4011 cds-NP_013216.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:324246-326825:+ gene-YLR115W_BG1 rna-NM_001182002.1_BG1 cds-NP_013216.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:371596-374172:+ gene-YLR115W_Bruggeman rna-NM_001182002.1_Bruggeman cds-NP_013216.1_Bruggeman 99.4 99.8 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:371509-374088:+ gene-YLR115W_CAT1 rna-NM_001182002.1_CAT1 cds-NP_013216.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:367611-370190:+ gene-YLR115W_CBS1585 rna-NM_001182002.1_CBS1585 cds-NP_013216.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:357851-360430:+ gene-YLR115W_CBS436 rna-NM_001182002.1_CBS436 cds-NP_013216.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:366029-368608:+ gene-YLR115W_CBS6412 rna-NM_001182002.1_CBS6412 cds-NP_013216.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:367876-370455:+ gene-YLR115W_CBS6413 rna-NM_001182002.1_CBS6413 cds-NP_013216.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:363007-365586:+ gene-YLR115W_CENPK1137D rna-NM_001182002.1_CENPK1137D cds-NP_013216.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:360668-363247:+ gene-YLR115W_EthanolRed rna-NM_001182002.1_EthanolRed cds-NP_013216.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:360179-362758:+ gene-YLR115W_FaliES1 rna-NM_001182002.1_FaliES1 cds-NP_013216.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000117.1:30437-33016:- gene-YLR115W_JAY291 rna-NM_001182002.1_JAY291 cds-NP_013216.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:367884-370463:+ gene-YLR115W_MUCL30387 rna-NM_001182002.1_MUCL30387 cds-NP_013216.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:376666-379245:+ gene-YLR115W_MUCL30388 rna-NM_001182002.1_MUCL30388 cds-NP_013216.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:368120-370699:+ gene-YLR115W_MUCL39482 rna-NM_001182002.1_MUCL39482 cds-NP_013216.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:368246-370825:+ gene-YLR115W_MUCL42920 rna-NM_001182002.1_MUCL42920 cds-NP_013216.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:377959-380538:+ gene-YLR115W_NCIM3186 rna-NM_001182002.1_NCIM3186 cds-NP_013216.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:360393-362972:+ gene-YLR115W_NCYC1407 rna-NM_001182002.1_NCYC1407 cds-NP_013216.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:365956-368535:+ gene-YLR115W_PE2H3 rna-NM_001182002.1_PE2H3 cds-NP_013216.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:365697-368276:+ gene-YLR115W_PE2H4 rna-NM_001182002.1_PE2H4 cds-NP_013216.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:377985-380564:+ gene-YLR115W_S288C rna-NM_001182002.1_S288C cds-NP_013216.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000055.1:3860-6439:+ gene-YLR115W_SA1 rna-NM_001182002.1_SA1 cds-NP_013216.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:361389-363968:+ gene-YLR115W_ThermosaccDry rna-NM_001182002.1_ThermosaccDry cds-NP_013216.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:373851-376430:+ gene-YLR115W_VR1 rna-NM_001182002.1_VR1 cds-NP_013216.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:359187-361766:+ gene-YLR115W_ZTW1 rna-NM_001182002.1_ZTW1 cds-NP_013216.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:369009-371600:+ gene-YLR115W_Sparadoxus rna-NM_001182002.1_Sparadoxus cds-NP_013216.1_Sparadoxus 90.0 99.9 Verified 1 1 1 False True False False False

Additional files