Gene name: CFT1
Reference locus (S288C): YDR301W
Gene biotype: protein_coding
Description: Protein CFT1; RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF
Top 10 interactors (score): RNA15 (0.999); FIP1 (0.999); YTH1 (0.999); SSU72 (0.999); PFS2 (0.999); MPE1 (0.999); TFC4 (0.999); CFT2 (0.999); PAP1 (0.999); PTA1 (0.999); PTI1 (0.999); REF2 (0.999); YSH1 (0.999); SYC1 (0.999); RNA14 (0.999); SWD2 (0.999); PCF11 (0.997); GLC7 (0.995); CLP1 (0.992); NUP170 (0.988)
Homologues (species, bitscore): CPSF1 (Homo sapiens, 248.4); Cpsf1 (Mus musculus, 255.0); cpsf1 (Danio rerio, 259.2); cpsf1 (Xenopus tropicalis, 100.1); Cpsf160 (Drosophila melanogaster, 249.2); cpsf-1 (Caenorhabditis elegans, 151.8); CPSF160 (Arabidopsis thaliana, 123.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1015364-1019437:+ | gene-YDR301W_AKU4011 | rna-NM_001180609.1_AKU4011 | cds-NP_010587.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:112138-116211:- | gene-YDR301W_BG1 | rna-NM_001180609.1_BG1 | cds-NP_010587.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1042631-1046704:+ | gene-YDR301W_Bruggeman | rna-NM_001180609.1_Bruggeman | cds-NP_010587.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1029629-1033702:+ | gene-YDR301W_CAT1 | rna-NM_001180609.1_CAT1 | cds-NP_010587.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1009809-1013882:+ | gene-YDR301W_CBS1585 | rna-NM_001180609.1_CBS1585 | cds-NP_010587.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1028180-1032253:+ | gene-YDR301W_CBS436 | rna-NM_001180609.1_CBS436 | cds-NP_010587.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1006491-1010564:+ | gene-YDR301W_CBS6412 | rna-NM_001180609.1_CBS6412 | cds-NP_010587.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1027729-1031802:+ | gene-YDR301W_CBS6413 | rna-NM_001180609.1_CBS6413 | cds-NP_010587.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1061994-1066067:+ | gene-YDR301W_CENPK1137D | rna-NM_001180609.1_CENPK1137D | cds-NP_010587.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1013719-1017792:+ | gene-YDR301W_EthanolRed | rna-NM_001180609.1_EthanolRed | cds-NP_010587.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1022121-1026194:+ | gene-YDR301W_FaliES1 | rna-NM_001180609.1_FaliES1 | cds-NP_010587.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000130.1:39914-43987:+ | gene-YDR301W_JAY291 | rna-NM_001180609.1_JAY291 | cds-NP_010587.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1028117-1032190:+ | gene-YDR301W_MUCL30387 | rna-NM_001180609.1_MUCL30387 | cds-NP_010587.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1015213-1019286:+ | gene-YDR301W_MUCL30388 | rna-NM_001180609.1_MUCL30388 | cds-NP_010587.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1001615-1005688:+ | gene-YDR301W_MUCL39482 | rna-NM_001180609.1_MUCL39482 | cds-NP_010587.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:941582-945655:+ | gene-YDR301W_MUCL42920 | rna-NM_001180609.1_MUCL42920 | cds-NP_010587.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1063275-1067348:+ | gene-YDR301W_NCIM3186 | rna-NM_001180609.1_NCIM3186 | cds-NP_010587.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1014908-1018981:+ | gene-YDR301W_NCYC1407 | rna-NM_001180609.1_NCYC1407 | cds-NP_010587.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1025887-1029960:+ | gene-YDR301W_PE2H3 | rna-NM_001180609.1_PE2H3 | cds-NP_010587.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1031472-1035545:+ | gene-YDR301W_PE2H4 | rna-NM_001180609.1_PE2H4 | cds-NP_010587.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1063352-1067425:+ | gene-YDR301W_S288C | rna-NM_001180609.1_S288C | cds-NP_010587.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:40087-44160:+ | gene-YDR301W_SA1 | rna-NM_001180609.1_SA1 | cds-NP_010587.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1026394-1030467:+ | gene-YDR301W_ThermosaccDry | rna-NM_001180609.1_ThermosaccDry | cds-NP_010587.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1042306-1046379:+ | gene-YDR301W_VR1 | rna-NM_001180609.1_VR1 | cds-NP_010587.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:70509-74582:+ | gene-YDR301W_ZTW1 | rna-NM_001180609.1_ZTW1 | cds-NP_010587.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1021938-1026026:+ | gene-YDR301W_Sparadoxus | rna-NM_001180609.1_Sparadoxus | cds-NP_010587.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |