CEM1 (YER061C)


Gene profile

Gene name: CEM1
Reference locus (S288C): YER061C
Gene biotype: protein_coding

Description: 3-oxoacyl-[acyl-carrier-protein] synthase homolog; Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respiration; human homolog OXSM can complement yeast cem1 null mutant; Belongs to the beta-ketoacyl-ACP synthases family

Top 10 interactors (score): ACP1 (0.996); OAR1 (0.988); FAS2 (0.987); MCT1 (0.98); ETR1 (0.969); FAS1 (0.96); DUR1,2 (0.933); ELO1 (0.864); HFA1 (0.863); LIP2 (0.85); ELO2 (0.828); ELO3 (0.828); FAA2 (0.8); ERG10 (0.776); AIM22 (0.714); TDA1 (0.7); OLE1 (0.694); POX1 (0.693); ACS2 (0.689); SHM2 (0.684)

Homologues (species, bitscore): OXSM (Homo sapiens, 297.4); Oxsm (Mus musculus, 297.4); OXSM (Danio rerio, 291.6); oxsm (Xenopus tropicalis, 288.5); CG12170 (Drosophila melanogaster, 291.6); F10G8.9 (Caenorhabditis elegans, 276.6); AT2G04540 (Arabidopsis thaliana, 313.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:272092-273420:- gene-YER061C_AKU4011 rna-NM_001178952.2_AKU4011 cds-NP_010983.2_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:152355-153683:+ gene-YER061C_BG1 rna-NM_001178952.2_BG1 cds-NP_010983.2_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:281404-282732:- gene-YER061C_Bruggeman rna-NM_001178952.2_Bruggeman cds-NP_010983.2_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:275047-276375:- gene-YER061C_CAT1 rna-NM_001178952.2_CAT1 cds-NP_010983.2_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:271948-273276:- gene-YER061C_CBS1585 rna-NM_001178952.2_CBS1585 cds-NP_010983.2_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:273858-275186:- gene-YER061C_CBS436 rna-NM_001178952.2_CBS436 cds-NP_010983.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:271418-272746:- gene-YER061C_CBS6412 rna-NM_001178952.2_CBS6412 cds-NP_010983.2_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:277424-278752:- gene-YER061C_CBS6413 rna-NM_001178952.2_CBS6413 cds-NP_010983.2_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:276151-277479:- gene-YER061C_CENPK1137D rna-NM_001178952.2_CENPK1137D cds-NP_010983.2_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:272432-273760:- gene-YER061C_EthanolRed rna-NM_001178952.2_EthanolRed cds-NP_010983.2_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:272885-274213:- gene-YER061C_FaliES1 rna-NM_001178952.2_FaliES1 cds-NP_010983.2_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000254.1:304-1632:- gene-YER061C_JAY291 rna-NM_001178952.2_JAY291 cds-NP_010983.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:276841-278169:- gene-YER061C_MUCL30387 rna-NM_001178952.2_MUCL30387 cds-NP_010983.2_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:272511-273839:- gene-YER061C_MUCL30388 rna-NM_001178952.2_MUCL30388 cds-NP_010983.2_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:270983-272311:- gene-YER061C_MUCL39482 rna-NM_001178952.2_MUCL39482 cds-NP_010983.2_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:278039-279367:- gene-YER061C_MUCL42920 rna-NM_001178952.2_MUCL42920 cds-NP_010983.2_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:278297-279625:- gene-YER061C_NCIM3186 rna-NM_001178952.2_NCIM3186 cds-NP_010983.2_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:276046-277374:- gene-YER061C_NCYC1407 rna-NM_001178952.2_NCYC1407 cds-NP_010983.2_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:286699-288027:- gene-YER061C_PE2H3 rna-NM_001178952.2_PE2H3 cds-NP_010983.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:276640-277968:- gene-YER061C_PE2H4 rna-NM_001178952.2_PE2H4 cds-NP_010983.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:278298-279626:- gene-YER061C_S288C rna-NM_001178952.2_S288C cds-NP_010983.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000059.1:64817-66145:- gene-YER061C_SA1 rna-NM_001178952.2_SA1 cds-NP_010983.2_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:273681-275009:- gene-YER061C_ThermosaccDry rna-NM_001178952.2_ThermosaccDry cds-NP_010983.2_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:273382-274710:- gene-YER061C_VR1 rna-NM_001178952.2_VR1 cds-NP_010983.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:270862-272190:- gene-YER061C_ZTW1 rna-NM_001178952.2_ZTW1 cds-NP_010983.2_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:274800-276128:- gene-YER061C_Sparadoxus rna-NM_001178952.2_Sparadoxus cds-NP_010983.2_Sparadoxus 88.5 99.8 Verified 1 1 1 False True False False False

Additional files