Gene name: CDH1
Reference locus (S288C): YGL003C
Gene biotype: protein_coding
Description: Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated; Belongs to the WD repeat CDC20/Fizzy family
Top 10 interactors (score): CDC16 (0.999); CLB2 (0.999); APC1 (0.999); CDC27 (0.999); CDC23 (0.999); CDC14 (0.999); APC2 (0.998); MAD2 (0.998); DOC1 (0.998); CDC5 (0.998); APC11 (0.997); CDC28 (0.997); ACM1 (0.995); CLB3 (0.992); BUB1 (0.989); CLB1 (0.987); APC4 (0.986); MAD3 (0.982); PDS1 (0.979); ESP1 (0.969)
Homologues (species, bitscore): FZR1 (Homo sapiens, 346.3); Fzr1 (Mus musculus, 344.0); fzr1 (Danio rerio, 342.0); fzr1 (Xenopus tropicalis, 349.0); rap (Drosophila melanogaster, 347.8); fzr-1 (Caenorhabditis elegans, 333.6); CCS52A2 (Arabidopsis thaliana, 342.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:494525-496225:- | gene-YGL003C_AKU4011 | rna-NM_001180868.1_AKU4011 | cds-NP_011512.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:79885-81585:+ | gene-YGL003C_BG1 | rna-NM_001180868.1_BG1 | cds-NP_011512.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:495494-497194:- | gene-YGL003C_Bruggeman | rna-NM_001180868.1_Bruggeman | cds-NP_011512.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:494038-495738:- | gene-YGL003C_CAT1 | rna-NM_001180868.1_CAT1 | cds-NP_011512.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:496019-497719:- | gene-YGL003C_CBS1585 | rna-NM_001180868.1_CBS1585 | cds-NP_011512.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:490380-492080:- | gene-YGL003C_CBS436 | rna-NM_001180868.1_CBS436 | cds-NP_011512.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:488614-490314:- | gene-YGL003C_CBS6412 | rna-NM_001180868.1_CBS6412 | cds-NP_011512.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:492690-494390:- | gene-YGL003C_CBS6413 | rna-NM_001180868.1_CBS6413 | cds-NP_011512.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:492291-493991:- | gene-YGL003C_CENPK1137D | rna-NM_001180868.1_CENPK1137D | cds-NP_011512.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:482896-484596:- | gene-YGL003C_EthanolRed | rna-NM_001180868.1_EthanolRed | cds-NP_011512.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:486148-487848:- | gene-YGL003C_FaliES1 | rna-NM_001180868.1_FaliES1 | cds-NP_011512.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:24779-26479:- | gene-YGL003C_JAY291 | rna-NM_001180868.1_JAY291 | cds-NP_011512.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:492716-494416:- | gene-YGL003C_MUCL30387 | rna-NM_001180868.1_MUCL30387 | cds-NP_011512.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:495266-496966:- | gene-YGL003C_MUCL30388 | rna-NM_001180868.1_MUCL30388 | cds-NP_011512.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:491837-493537:- | gene-YGL003C_MUCL39482 | rna-NM_001180868.1_MUCL39482 | cds-NP_011512.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:501269-502969:- | gene-YGL003C_MUCL42920 | rna-NM_001180868.1_MUCL42920 | cds-NP_011512.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:492474-494174:- | gene-YGL003C_NCIM3186 | rna-NM_001180868.1_NCIM3186 | cds-NP_011512.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:485878-487578:- | gene-YGL003C_NCYC1407 | rna-NM_001180868.1_NCYC1407 | cds-NP_011512.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:488547-490247:- | gene-YGL003C_PE2H3 | rna-NM_001180868.1_PE2H3 | cds-NP_011512.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:493597-495297:- | gene-YGL003C_PE2H4 | rna-NM_001180868.1_PE2H4 | cds-NP_011512.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:492474-494174:- | gene-YGL003C_S288C | rna-NM_001180868.1_S288C | cds-NP_011512.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:61408-63108:+ | gene-YGL003C_SA1 | rna-NM_001180868.1_SA1 | cds-NP_011512.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:505473-507173:- | gene-YGL003C_ThermosaccDry | rna-NM_001180868.1_ThermosaccDry | cds-NP_011512.1_ThermosaccDry | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:595509-597209:- | gene-YGL003C_VR1 | rna-NM_001180868.1_VR1 | cds-NP_011512.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:484072-485772:- | gene-YGL003C_ZTW1 | rna-NM_001180868.1_ZTW1 | cds-NP_011512.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:493668-495368:- | gene-YGL003C_Sparadoxus | rna-NM_001180868.1_Sparadoxus | cds-NP_011512.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |