Gene name: CDC9
Reference locus (S288C): YDL164C
Gene biotype: protein_coding
Description: DNA ligase I found in nucleus and mitochondria; essential enzyme that joins Okazaki fragments during DNA replication; also acts in ribonucleotide excision repair, base excision repair, and recombination; DNA ligase I mutants trigger ubiquitination of PCNA at K107, facilitating Rad59p-mediated bypass of unligated Okazaki fragments; human homolog LIG1 can complement yeast cdc9 temperature-sensitive mutant at restrictive temperature; Belongs to the ATP-dependent DNA ligase family
Top 10 interactors (score): POL30 (0.999); RAD27 (0.999); CHK1 (0.995); POL3 (0.995); POL1 (0.992); RAD23 (0.989); DNA2 (0.989); POL2 (0.989); CDC45 (0.982); CTF4 (0.982); MCM6 (0.979); MSH6 (0.977); RFA1 (0.977); CDC21 (0.976); MSH2 (0.975); POL12 (0.972); CTF18 (0.971); CDC6 (0.969); MCM7 (0.969); ZWF1 (0.965)
Homologues (species, bitscore): LIG1 (Homo sapiens, 575.1); Lig1 (Mus musculus, 564.3); LIG1 (Danio rerio, 588.6); lig1 (Xenopus tropicalis, 602.1); DNA-ligI (Drosophila melanogaster, 581.3); lig-1 (Caenorhabditis elegans, 545.8); LIG1 (Arabidopsis thaliana, 590.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:149404-151671:- | gene-YDL164C_AKU4011 | rna-NM_001180224.1_AKU4011 | cds-NP_010117.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:398058-400325:+ | gene-YDL164C_BG1 | rna-NM_001180224.1_BG1 | cds-NP_010117.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:165471-167738:- | gene-YDL164C_Bruggeman | rna-NM_001180224.1_Bruggeman | cds-NP_010117.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:163776-166043:- | gene-YDL164C_CAT1 | rna-NM_001180224.1_CAT1 | cds-NP_010117.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:147440-149707:- | gene-YDL164C_CBS1585 | rna-NM_001180224.1_CBS1585 | cds-NP_010117.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:164400-166667:- | gene-YDL164C_CBS436 | rna-NM_001180224.1_CBS436 | cds-NP_010117.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:147055-149322:- | gene-YDL164C_CBS6412 | rna-NM_001180224.1_CBS6412 | cds-NP_010117.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:165866-168133:- | gene-YDL164C_CBS6413 | rna-NM_001180224.1_CBS6413 | cds-NP_010117.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:163662-165929:- | gene-YDL164C_CENPK1137D | rna-NM_001180224.1_CENPK1137D | cds-NP_010117.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:160867-163134:- | gene-YDL164C_EthanolRed | rna-NM_001180224.1_EthanolRed | cds-NP_010117.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:166193-168460:- | gene-YDL164C_FaliES1 | rna-NM_001180224.1_FaliES1 | cds-NP_010117.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:51105-53372:+ | gene-YDL164C_JAY291 | rna-NM_001180224.1_JAY291 | cds-NP_010117.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:163765-166032:- | gene-YDL164C_MUCL30387 | rna-NM_001180224.1_MUCL30387 | cds-NP_010117.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:155414-157681:- | gene-YDL164C_MUCL30388 | rna-NM_001180224.1_MUCL30388 | cds-NP_010117.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:148583-150850:- | gene-YDL164C_MUCL39482 | rna-NM_001180224.1_MUCL39482 | cds-NP_010117.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:18512-20779:+ | gene-YDL164C_MUCL42920 | rna-NM_001180224.1_MUCL42920 | cds-NP_010117.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:164910-167177:- | gene-YDL164C_NCIM3186 | rna-NM_001180224.1_NCIM3186 | cds-NP_010117.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:148523-150790:- | gene-YDL164C_NCYC1407 | rna-NM_001180224.1_NCYC1407 | cds-NP_010117.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:155767-158034:- | gene-YDL164C_PE2H3 | rna-NM_001180224.1_PE2H3 | cds-NP_010117.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:155771-158038:- | gene-YDL164C_PE2H4 | rna-NM_001180224.1_PE2H4 | cds-NP_010117.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:164987-167254:- | gene-YDL164C_S288C | rna-NM_001180224.1_S288C | cds-NP_010117.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:30541-32808:- | gene-YDL164C_SA1 | rna-NM_001180224.1_SA1 | cds-NP_010117.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:165953-168220:- | gene-YDL164C_ThermosaccDry | rna-NM_001180224.1_ThermosaccDry | cds-NP_010117.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:166538-168805:- | gene-YDL164C_VR1 | rna-NM_001180224.1_VR1 | cds-NP_010117.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:164083-166350:- | gene-YDL164C_ZTW1 | rna-NM_001180224.1_ZTW1 | cds-NP_010117.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:166192-168459:- | gene-YDL164C_Sparadoxus | rna-NM_001180224.1_Sparadoxus | cds-NP_010117.1_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |