Gene name: CDC8
Reference locus (S288C): YJR057W
Gene biotype: protein_coding
Description: Thymidylate and uridylate kinase; functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe tmp1; human homolog DTYMK can complement yeast cdc8 null mutant
Top 10 interactors (score): CDC21 (0.998); DUT1 (0.997); YNK1 (0.996); URA6 (0.977); RNR3 (0.972); DCD1 (0.97); RNR1 (0.967); RNR4 (0.955); RNR2 (0.952); CDC9 (0.943); YND1 (0.913); MAD2 (0.887); CDC7 (0.869); CCT6 (0.851); GUK1 (0.802); RFC2 (0.791); CDC4 (0.79); TOM40 (0.79); URA3 (0.74); RNH201 (0.737)
Homologues (species, bitscore): DTYMK (Homo sapiens, 161.8); Dtymk (Mus musculus, 161.4); dtymk (Danio rerio, 170.6); dtymk (Xenopus tropicalis, 159.1); CG5757 (Drosophila melanogaster, 163.7); R53.2 (Caenorhabditis elegans, 126.3); ZEU1 (Arabidopsis thaliana, 166.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:515593-516243:+ | gene-YJR057W_AKU4011 | rna-NM_001181715.1_AKU4011 | cds-NP_012591.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:91380-92030:- | gene-YJR057W_BG1 | rna-NM_001181715.1_BG1 | cds-NP_012591.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:529099-529749:+ | gene-YJR057W_Bruggeman | rna-NM_001181715.1_Bruggeman | cds-NP_012591.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:533412-534062:+ | gene-YJR057W_CAT1 | rna-NM_001181715.1_CAT1 | cds-NP_012591.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:527657-528307:+ | gene-YJR057W_CBS1585 | rna-NM_001181715.1_CBS1585 | cds-NP_012591.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:545726-546376:+ | gene-YJR057W_CBS436 | rna-NM_001181715.1_CBS436 | cds-NP_012591.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:514806-515456:+ | gene-YJR057W_CBS6412 | rna-NM_001181715.1_CBS6412 | cds-NP_012591.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:517102-517752:+ | gene-YJR057W_CBS6413 | rna-NM_001181715.1_CBS6413 | cds-NP_012591.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:526420-527070:+ | gene-YJR057W_CENPK1137D | rna-NM_001181715.1_CENPK1137D | cds-NP_012591.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:519986-520636:+ | gene-YJR057W_EthanolRed | rna-NM_001181715.1_EthanolRed | cds-NP_012591.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:531452-532102:+ | gene-YJR057W_FaliES1 | rna-NM_001181715.1_FaliES1 | cds-NP_012591.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:157287-157937:- | gene-YJR057W_JAY291 | rna-NM_001181715.1_JAY291 | cds-NP_012591.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:529637-530287:+ | gene-YJR057W_MUCL30387 | rna-NM_001181715.1_MUCL30387 | cds-NP_012591.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:526911-527561:+ | gene-YJR057W_MUCL30388 | rna-NM_001181715.1_MUCL30388 | cds-NP_012591.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:521119-521769:+ | gene-YJR057W_MUCL39482 | rna-NM_001181715.1_MUCL39482 | cds-NP_012591.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:525346-525996:+ | gene-YJR057W_MUCL42920 | rna-NM_001181715.1_MUCL42920 | cds-NP_012591.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:544041-544691:+ | gene-YJR057W_NCIM3186 | rna-NM_001181715.1_NCIM3186 | cds-NP_012591.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:518683-519333:+ | gene-YJR057W_NCYC1407 | rna-NM_001181715.1_NCYC1407 | cds-NP_012591.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:536575-537225:+ | gene-YJR057W_PE2H3 | rna-NM_001181715.1_PE2H3 | cds-NP_012591.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:530271-530921:+ | gene-YJR057W_PE2H4 | rna-NM_001181715.1_PE2H4 | cds-NP_012591.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:544062-544712:+ | gene-YJR057W_S288C | rna-NM_001181715.1_S288C | cds-NP_012591.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:2641-3291:+ | gene-YJR057W_SA1 | rna-NM_001181715.1_SA1 | cds-NP_012591.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:525382-526032:+ | gene-YJR057W_ThermosaccDry | rna-NM_001181715.1_ThermosaccDry | cds-NP_012591.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:527261-527911:+ | gene-YJR057W_VR1 | rna-NM_001181715.1_VR1 | cds-NP_012591.1_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:504771-505421:+ | gene-YJR057W_ZTW1 | rna-NM_001181715.1_ZTW1 | cds-NP_012591.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:538185-538835:+ | gene-YJR057W_Sparadoxus | rna-NM_001181715.1_Sparadoxus | cds-NP_012591.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |