Gene name: CDC7
Reference locus (S288C): YDL017W
Gene biotype: protein_coding
Description: Cell division control protein 7; DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily
Top 10 interactors (score): MCM6 (0.999); MCM2 (0.999); DBF4 (0.999); MCM4 (0.999); MCM5 (0.999); MCM10 (0.999); RAD53 (0.999); CDC45 (0.998); CDC6 (0.997); MCM7 (0.997); MRC1 (0.997); MCM3 (0.991); ORC5 (0.987); CHK1 (0.98); POL1 (0.979); ORC2 (0.975); ORC1 (0.971); CDC5 (0.966); DPB11 (0.963); POL2 (0.96)
Homologues (species, bitscore): CDC7 (Homo sapiens, 167.5); Cdc7 (Mus musculus, 170.2); cdc7 (Danio rerio, 172.9); cdc7 (Xenopus tropicalis, 167.5); CG5790 (Drosophila melanogaster, 156.0); cdc-7 (Caenorhabditis elegans, 94.4); CKA2 (Arabidopsis thaliana, 89.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:410296-411819:+ | gene-YDL017W_AKU4011 | rna-NM_001180076.3_AKU4011 | cds-NP_010267.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:138067-139590:- | gene-YDL017W_BG1 | rna-NM_001180076.3_BG1 | cds-NP_010267.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:430862-432385:+ | gene-YDL017W_Bruggeman | rna-NM_001180076.3_Bruggeman | cds-NP_010267.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:423758-425281:+ | gene-YDL017W_CAT1 | rna-NM_001180076.3_CAT1 | cds-NP_010267.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:406709-408232:+ | gene-YDL017W_CBS1585 | rna-NM_001180076.3_CBS1585 | cds-NP_010267.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:424234-425757:+ | gene-YDL017W_CBS436 | rna-NM_001180076.3_CBS436 | cds-NP_010267.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:404478-406001:+ | gene-YDL017W_CBS6412 | rna-NM_001180076.3_CBS6412 | cds-NP_010267.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:426475-427998:+ | gene-YDL017W_CBS6413 | rna-NM_001180076.3_CBS6413 | cds-NP_010267.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:423072-424595:+ | gene-YDL017W_CENPK1137D | rna-NM_001180076.3_CENPK1137D | cds-NP_010267.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:419128-420651:+ | gene-YDL017W_EthanolRed | rna-NM_001180076.3_EthanolRed | cds-NP_010267.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:425320-426843:+ | gene-YDL017W_FaliES1 | rna-NM_001180076.3_FaliES1 | cds-NP_010267.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000370.1:39803-41326:+ | gene-YDL017W_JAY291 | rna-NM_001180076.3_JAY291 | cds-NP_010267.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:424752-426275:+ | gene-YDL017W_MUCL30387 | rna-NM_001180076.3_MUCL30387 | cds-NP_010267.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:415208-416731:+ | gene-YDL017W_MUCL30388 | rna-NM_001180076.3_MUCL30388 | cds-NP_010267.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:408383-409906:+ | gene-YDL017W_MUCL39482 | rna-NM_001180076.3_MUCL39482 | cds-NP_010267.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:330260-331783:+ | gene-YDL017W_MUCL42920 | rna-NM_001180076.3_MUCL42920 | cds-NP_010267.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:424132-425655:+ | gene-YDL017W_NCIM3186 | rna-NM_001180076.3_NCIM3186 | cds-NP_010267.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:407805-409328:+ | gene-YDL017W_NCYC1407 | rna-NM_001180076.3_NCYC1407 | cds-NP_010267.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:415285-416808:+ | gene-YDL017W_PE2H3 | rna-NM_001180076.3_PE2H3 | cds-NP_010267.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:414643-416166:+ | gene-YDL017W_PE2H4 | rna-NM_001180076.3_PE2H4 | cds-NP_010267.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:424209-425732:+ | gene-YDL017W_S288C | rna-NM_001180076.3_S288C | cds-NP_010267.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:9234-10757:- | gene-YDL017W_SA1 | rna-NM_001180076.3_SA1 | cds-NP_010267.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:424780-426303:+ | gene-YDL017W_ThermosaccDry | rna-NM_001180076.3_ThermosaccDry | cds-NP_010267.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:427790-429313:+ | gene-YDL017W_VR1 | rna-NM_001180076.3_VR1 | cds-NP_010267.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:422679-424202:+ | gene-YDL017W_ZTW1 | rna-NM_001180076.3_ZTW1 | cds-NP_010267.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:426827-428350:+ | gene-YDL017W_Sparadoxus | rna-NM_001180076.3_Sparadoxus | cds-NP_010267.3_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |