Gene name: CDC6
Reference locus (S288C): YJL194W
Gene biotype: protein_coding
Description: Cell division control protein 6; Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress
Top 10 interactors (score): MCM10 (0.999); MCM3 (0.999); MCM5 (0.999); ORC5 (0.999); CLB2 (0.999); ORC6 (0.999); MCM4 (0.999); ORC1 (0.999); CDC28 (0.999); ORC2 (0.999); ORC4 (0.999); ORC3 (0.999); PSF3 (0.999); MCM7 (0.999); CDC45 (0.999); MCM2 (0.999); MCM6 (0.999); CDC4 (0.999); TAH11 (0.999); POL1 (0.998)
Homologues (species, bitscore): CDC6 (Homo sapiens, 143.7); Cdc6 (Mus musculus, 152.1); cdc6 (Danio rerio, 126.7); cdc6 (Xenopus tropicalis, 152.9); Cdc6 (Drosophila melanogaster, 134.8); cdc-6 (Caenorhabditis elegans, 104.4); AT1G07270 (Arabidopsis thaliana, 155.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:57737-59278:+ | gene-YJL194W_AKU4011 | rna-NM_001181627.1_AKU4011 | cds-NP_012341.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000181.1:35017-36558:+ | gene-YJL194W_BG1 | rna-NM_001181627.1_BG1 | cds-NP_012341.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:69549-71090:+ | gene-YJL194W_Bruggeman | rna-NM_001181627.1_Bruggeman | cds-NP_012341.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:72758-74299:+ | gene-YJL194W_CAT1 | rna-NM_001181627.1_CAT1 | cds-NP_012341.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:63372-64913:+ | gene-YJL194W_CBS1585 | rna-NM_001181627.1_CBS1585 | cds-NP_012341.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:88119-89660:+ | gene-YJL194W_CBS436 | rna-NM_001181627.1_CBS436 | cds-NP_012341.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:59854-61395:+ | gene-YJL194W_CBS6412 | rna-NM_001181627.1_CBS6412 | cds-NP_012341.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:60847-62388:+ | gene-YJL194W_CBS6413 | rna-NM_001181627.1_CBS6413 | cds-NP_012341.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:51803-53344:+ | gene-YJL194W_CENPK1137D | rna-NM_001181627.1_CENPK1137D | cds-NP_012341.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:62034-63575:+ | gene-YJL194W_EthanolRed | rna-NM_001181627.1_EthanolRed | cds-NP_012341.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:67314-68855:+ | gene-YJL194W_FaliES1 | rna-NM_001181627.1_FaliES1 | cds-NP_012341.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000164.1:49894-51435:- | gene-YJL194W_JAY291 | rna-NM_001181627.1_JAY291 | cds-NP_012341.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:71283-72824:+ | gene-YJL194W_MUCL30387 | rna-NM_001181627.1_MUCL30387 | cds-NP_012341.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:67438-68979:+ | gene-YJL194W_MUCL30388 | rna-NM_001181627.1_MUCL30388 | cds-NP_012341.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:62114-63655:+ | gene-YJL194W_MUCL39482 | rna-NM_001181627.1_MUCL39482 | cds-NP_012341.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:66709-68250:+ | gene-YJL194W_MUCL42920 | rna-NM_001181627.1_MUCL42920 | cds-NP_012341.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:69317-70858:+ | gene-YJL194W_NCIM3186 | rna-NM_001181627.1_NCIM3186 | cds-NP_012341.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:60724-62265:+ | gene-YJL194W_NCYC1407 | rna-NM_001181627.1_NCYC1407 | cds-NP_012341.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:73417-74958:+ | gene-YJL194W_PE2H3 | rna-NM_001181627.1_PE2H3 | cds-NP_012341.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:73056-74597:+ | gene-YJL194W_PE2H4 | rna-NM_001181627.1_PE2H4 | cds-NP_012341.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:69338-70879:+ | gene-YJL194W_S288C | rna-NM_001181627.1_S288C | cds-NP_012341.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000022.1:83004-84545:- | gene-YJL194W_SA1 | rna-NM_001181627.1_SA1 | cds-NP_012341.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:60506-62047:+ | gene-YJL194W_ThermosaccDry | rna-NM_001181627.1_ThermosaccDry | cds-NP_012341.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:67376-68917:+ | gene-YJL194W_VR1 | rna-NM_001181627.1_VR1 | cds-NP_012341.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:48091-49632:+ | gene-YJL194W_ZTW1 | rna-NM_001181627.1_ZTW1 | cds-NP_012341.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:72393-73934:+ | gene-YJL194W_Sparadoxus | rna-NM_001181627.1_Sparadoxus | cds-NP_012341.1_Sparadoxus | 89.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |