CDC55 (YGL190C)


Gene profile

Gene name: CDC55
Reference locus (S288C): YGL190C
Gene biotype: protein_coding

Description: Regulatory subunit B of protein phosphatase 2A (PP2A); Zds1p/2p-dependent localization to cytoplasm promotes mitotic entry; localization to nucleus prevents mitotic exit; required for correct nuclear division, chromosome segregation during achiasmate meiosis; maintains nucleolar sequestration of Cdc14p during early meiosis; limits formation of PP2A-Rts1p holocomplexes to ensure timely dissolution of sister chromosome cohesion; homolog of mammalian B55

Top 10 interactors (score): RTS1 (0.999); SIT4 (0.999); PPH22 (0.999); PPH21 (0.999); TPD3 (0.999); PPM1 (0.997); NET1 (0.995); PPH3 (0.995); ZDS2 (0.993); YNL217W (0.991); RRD2 (0.99); IGO1 (0.988); GLC7 (0.987); ESP1 (0.987); ZDS1 (0.979); IGO2 (0.979); SWE1 (0.977); CCT5 (0.971); CCT2 (0.971); SLK19 (0.971)

Homologues (species, bitscore): PPP2R2D (Homo sapiens, 453.0); Ppp2r2d (Mus musculus, 454.5); zgc:76887 (Danio rerio, 456.1); ppp2r2b (Xenopus tropicalis, 444.9); tws (Drosophila melanogaster, 449.9); sur-6 (Caenorhabditis elegans, 446.0); PP2AB2 (Arabidopsis thaliana, 449.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:148347-149927:- gene-YGL190C_AKU4011 rna-NM_001181055.1_AKU4011 cds-NP_011325.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:260517-262097:+ gene-YGL190C_BG1 rna-NM_001181055.1_BG1 cds-NP_011325.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:150583-152163:- gene-YGL190C_Bruggeman rna-NM_001181055.1_Bruggeman cds-NP_011325.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:146445-148025:- gene-YGL190C_CAT1 rna-NM_001181055.1_CAT1 cds-NP_011325.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:151486-153066:- gene-YGL190C_CBS1585 rna-NM_001181055.1_CBS1585 cds-NP_011325.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:146463-148043:- gene-YGL190C_CBS436 rna-NM_001181055.1_CBS436 cds-NP_011325.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:138264-139844:- gene-YGL190C_CBS6412 rna-NM_001181055.1_CBS6412 cds-NP_011325.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:145798-147378:- gene-YGL190C_CBS6413 rna-NM_001181055.1_CBS6413 cds-NP_011325.1_CBS6413 99.8 100.0 Unannotated 1 1 0 False False False False True
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:146004-147584:- gene-YGL190C_CENPK1137D rna-NM_001181055.1_CENPK1137D cds-NP_011325.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:138330-139910:- gene-YGL190C_EthanolRed rna-NM_001181055.1_EthanolRed cds-NP_011325.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:139330-140910:- gene-YGL190C_FaliES1 rna-NM_001181055.1_FaliES1 cds-NP_011325.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000397.1:64654-66234:- gene-YGL190C_JAY291 rna-NM_001181055.1_JAY291 cds-NP_011325.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:147819-149399:- gene-YGL190C_MUCL30387 rna-NM_001181055.1_MUCL30387 cds-NP_011325.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:150920-152500:- gene-YGL190C_MUCL30388 rna-NM_001181055.1_MUCL30388 cds-NP_011325.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:148496-150076:- gene-YGL190C_MUCL39482 rna-NM_001181055.1_MUCL39482 cds-NP_011325.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:151126-152706:- gene-YGL190C_MUCL42920 rna-NM_001181055.1_MUCL42920 cds-NP_011325.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:145809-147389:- gene-YGL190C_NCIM3186 rna-NM_001181055.1_NCIM3186 cds-NP_011325.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:139977-141557:- gene-YGL190C_NCYC1407 rna-NM_001181055.1_NCYC1407 cds-NP_011325.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:141966-143546:- gene-YGL190C_PE2H3 rna-NM_001181055.1_PE2H3 cds-NP_011325.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:141514-143094:- gene-YGL190C_PE2H4 rna-NM_001181055.1_PE2H4 cds-NP_011325.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:145809-147389:- gene-YGL190C_S288C rna-NM_001181055.1_S288C cds-NP_011325.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000067.1:5567-7147:- gene-YGL190C_SA1 rna-NM_001181055.1_SA1 cds-NP_011325.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:139592-141172:- gene-YGL190C_ThermosaccDry rna-NM_001181055.1_ThermosaccDry cds-NP_011325.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:146870-148450:- gene-YGL190C_VR1 rna-NM_001181055.1_VR1 cds-NP_011325.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:138129-139709:- gene-YGL190C_ZTW1 rna-NM_001181055.1_ZTW1 cds-NP_011325.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:145018-146598:- gene-YGL190C_Sparadoxus rna-NM_001181055.1_Sparadoxus cds-NP_011325.1_Sparadoxus 95.0 100.0 Verified 1 1 1 False True False False False

Additional files