Gene name: CDC53
Reference locus (S288C): YDL132W
Gene biotype: protein_coding
Description: Cell division control protein 53; Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant
Top 10 interactors (score): DCN1 (0.999); GRR1 (0.999); UBC12 (0.999); HRT1 (0.999); CDC4 (0.999); SKP1 (0.999); RRI1 (0.999); CDC34 (0.999); MET30 (0.999); RUB1 (0.998); ELC1 (0.997); HRT3 (0.997); RRT13 (0.993); UFO1 (0.991); CUL3 (0.99); SIC1 (0.985); UBI4 (0.982); APC11 (0.982); UBA3 (0.982); ULA1 (0.97)
Homologues (species, bitscore): CUL1 (Homo sapiens, 414.5); Cul1 (Mus musculus, 414.1); cul1a (Danio rerio, 401.7); cul1 (Xenopus tropicalis, 409.1); Cul1 (Drosophila melanogaster, 365.2); cul-1 (Caenorhabditis elegans, 356.3); CUL3B (Arabidopsis thaliana, 219.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:208947-211394:+ | gene-YDL132W_AKU4011 | rna-NM_001180191.1_AKU4011 | cds-NP_010150.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:338576-341023:- | gene-YDL132W_BG1 | rna-NM_001180191.1_BG1 | cds-NP_010150.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:225616-228063:+ | gene-YDL132W_Bruggeman | rna-NM_001180191.1_Bruggeman | cds-NP_010150.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:129211-131658:+ | gene-YDL132W_CAT1 | rna-NM_001180191.1_CAT1 | cds-NP_010150.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:207210-209657:+ | gene-YDL132W_CBS1585 | rna-NM_001180191.1_CBS1585 | cds-NP_010150.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:223877-226324:+ | gene-YDL132W_CBS436 | rna-NM_001180191.1_CBS436 | cds-NP_010150.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:206014-208461:+ | gene-YDL132W_CBS6412 | rna-NM_001180191.1_CBS6412 | cds-NP_010150.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:225372-227819:+ | gene-YDL132W_CBS6413 | rna-NM_001180191.1_CBS6413 | cds-NP_010150.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:222954-225401:+ | gene-YDL132W_CENPK1137D | rna-NM_001180191.1_CENPK1137D | cds-NP_010150.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:219978-222425:+ | gene-YDL132W_EthanolRed | rna-NM_001180191.1_EthanolRed | cds-NP_010150.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:225699-228146:+ | gene-YDL132W_FaliES1 | rna-NM_001180191.1_FaliES1 | cds-NP_010150.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000204.1:957-3404:- | gene-YDL132W_JAY291 | rna-NM_001180191.1_JAY291 | cds-NP_010150.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:224064-226511:+ | gene-YDL132W_MUCL30387 | rna-NM_001180191.1_MUCL30387 | cds-NP_010150.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:214932-217379:+ | gene-YDL132W_MUCL30388 | rna-NM_001180191.1_MUCL30388 | cds-NP_010150.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:208064-210511:+ | gene-YDL132W_MUCL39482 | rna-NM_001180191.1_MUCL39482 | cds-NP_010150.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000146.1:1106-3553:- | gene-YDL132W_MUCL42920 | rna-NM_001180191.1_MUCL42920 | cds-NP_010150.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:224227-226674:+ | gene-YDL132W_NCIM3186 | rna-NM_001180191.1_NCIM3186 | cds-NP_010150.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:208345-210792:+ | gene-YDL132W_NCYC1407 | rna-NM_001180191.1_NCYC1407 | cds-NP_010150.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:215104-217551:+ | gene-YDL132W_PE2H3 | rna-NM_001180191.1_PE2H3 | cds-NP_010150.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:215108-217555:+ | gene-YDL132W_PE2H4 | rna-NM_001180191.1_PE2H4 | cds-NP_010150.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:224304-226751:+ | gene-YDL132W_S288C | rna-NM_001180191.1_S288C | cds-NP_010150.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:89868-92315:+ | gene-YDL132W_SA1 | rna-NM_001180191.1_SA1 | cds-NP_010150.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:225460-227907:+ | gene-YDL132W_ThermosaccDry | rna-NM_001180191.1_ThermosaccDry | cds-NP_010150.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:227079-229526:+ | gene-YDL132W_VR1 | rna-NM_001180191.1_VR1 | cds-NP_010150.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:223388-225835:+ | gene-YDL132W_ZTW1 | rna-NM_001180191.1_ZTW1 | cds-NP_010150.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:225484-227931:+ | gene-YDL132W_Sparadoxus | rna-NM_001180191.1_Sparadoxus | cds-NP_010150.1_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |