CDC50 (YCR094W)


Gene profile

Gene name: CDC50
Reference locus (S288C): YCR094W
Gene biotype: protein_coding

Description: Cell division control protein 50; Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication

Top 10 interactors (score): DRS2 (0.999); DNF1 (0.998); DNF3 (0.994); DNF2 (0.973); NEO1 (0.97); RCY1 (0.915); LEM3 (0.909); SNC1 (0.874); CHO1 (0.717); YPT31 (0.707); GCS1 (0.698); GEA2 (0.696); KIN82 (0.695); PAN2 (0.684); KES1 (0.683); YPT52 (0.66); YPT10 (0.652); MON2 (0.644); SEC7 (0.641); SWA2 (0.635)

Homologues (species, bitscore): TMEM30A (Homo sapiens, 211.1); Tmem30a (Mus musculus, 205.7); tmem30ab (Danio rerio, 211.1); tmem30a (Xenopus tropicalis, 210.7); CG9947 (Drosophila melanogaster, 204.9); chat-1 (Caenorhabditis elegans, 197.6); ALIS1 (Arabidopsis thaliana, 175.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:281702-282877:+ gene-YCR094W_AKU4011 rna-NM_001178800.1_AKU4011 cds-NP_010018.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000067.1:140004-141179:+ gene-YCR094W_BG1 rna-NM_001178800.1_BG1 cds-NP_010018.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:278514-279689:+ gene-YCR094W_Bruggeman rna-NM_001178800.1_Bruggeman cds-NP_010018.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:288509-289684:+ gene-YCR094W_CAT1 rna-NM_001178800.1_CAT1 cds-NP_010018.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:276449-277624:+ gene-YCR094W_CBS1585 rna-NM_001178800.1_CBS1585 cds-NP_010018.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:287841-289016:+ gene-YCR094W_CBS436 rna-NM_001178800.1_CBS436 cds-NP_010018.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:267596-268771:+ gene-YCR094W_CBS6412 rna-NM_001178800.1_CBS6412 cds-NP_010018.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:282148-283323:+ gene-YCR094W_CBS6413 rna-NM_001178800.1_CBS6413 cds-NP_010018.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:285993-287168:+ gene-YCR094W_CENPK1137D rna-NM_001178800.1_CENPK1137D cds-NP_010018.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:277347-278522:+ gene-YCR094W_EthanolRed rna-NM_001178800.1_EthanolRed cds-NP_010018.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:283447-284622:+ gene-YCR094W_FaliES1 rna-NM_001178800.1_FaliES1 cds-NP_010018.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000323.1:5189-6364:- gene-YCR094W_JAY291 rna-NM_001178800.1_JAY291 cds-NP_010018.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:275315-276490:+ gene-YCR094W_MUCL30387 rna-NM_001178800.1_MUCL30387 cds-NP_010018.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:274136-275311:+ gene-YCR094W_MUCL30388 rna-NM_001178800.1_MUCL30388 cds-NP_010018.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:283093-284268:+ gene-YCR094W_MUCL39482 rna-NM_001178800.1_MUCL39482 cds-NP_010018.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:279304-280479:+ gene-YCR094W_MUCL42920 rna-NM_001178800.1_MUCL42920 cds-NP_010018.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:286394-287569:+ gene-YCR094W_NCIM3186 rna-NM_001178800.1_NCIM3186 cds-NP_010018.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:283736-284911:+ gene-YCR094W_NCYC1407 rna-NM_001178800.1_NCYC1407 cds-NP_010018.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:298022-299197:+ gene-YCR094W_PE2H3 rna-NM_001178800.1_PE2H3 cds-NP_010018.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:286574-287749:+ gene-YCR094W_PE2H4 rna-NM_001178800.1_PE2H4 cds-NP_010018.1_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:286762-287937:+ gene-YCR094W_S288C rna-NM_001178800.1_S288C cds-NP_010018.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000044.1:86748-87923:+ gene-YCR094W_SA1 rna-NM_001178800.1_SA1 cds-NP_010018.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:283401-284576:+ gene-YCR094W_ThermosaccDry rna-NM_001178800.1_ThermosaccDry cds-NP_010018.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:293562-294737:+ gene-YCR094W_VR1 rna-NM_001178800.1_VR1 cds-NP_010018.1_VR1 99.0 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:280105-281280:+ gene-YCR094W_ZTW1 rna-NM_001178800.1_ZTW1 cds-NP_010018.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:314480-315652:+ gene-YCR094W_Sparadoxus rna-NM_001178800.1_Sparadoxus cds-NP_010018.1_Sparadoxus 90.6 99.7 Verified 1 1 1 False True False False False

Additional files