CDC42 (YLR229C)


Gene profile

Gene name: CDC42
Reference locus (S288C): YLR229C
Gene biotype: protein_coding

Description: Cell division control protein 42; Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant

Top 10 interactors (score): EXO70 (0.999); SKM1 (0.999); LAS17 (0.999); CLA4 (0.999); BEM1 (0.999); RDI1 (0.999); BNI1 (0.999); RGA1 (0.999); STE20 (0.999); CDC24 (0.999); BZZ1 (0.999); IQG1 (0.999); RGA2 (0.998); ACT1 (0.998); GIC1 (0.998); BEM3 (0.998); GIC2 (0.998); PKC1 (0.997); SHO1 (0.997); SEC15 (0.995)

Homologues (species, bitscore): CDC42 (Homo sapiens, 325.5); Cdc42 (Mus musculus, 325.5); cdc42 (Danio rerio, 324.7); cdc42 (Xenopus tropicalis, 324.3); Cdc42 (Drosophila melanogaster, 322.4); cdc-42 (Caenorhabditis elegans, 317.4); RAC3 (Arabidopsis thaliana, 222.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:558374-558949:- gene-YLR229C_AKU4011 rna-NM_001182116.1_AKU4011 cds-NP_013330.1_AKU4011 99.4 100.0 Mismatch 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000082.1:12435-13010:- gene-YLR229C_BG1 rna-NM_001182116.1_BG1 cds-NP_013330.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:592658-593233:- gene-YLR229C_Bruggeman rna-NM_001182116.1_Bruggeman cds-NP_013330.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:591781-592356:- gene-YLR229C_CAT1 rna-NM_001182116.1_CAT1 cds-NP_013330.1_CAT1 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:593868-594443:- gene-YLR229C_CBS1585 rna-NM_001182116.1_CBS1585 cds-NP_013330.1_CBS1585 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:578125-578700:- gene-YLR229C_CBS436 rna-NM_001182116.1_CBS436 cds-NP_013330.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:556843-557418:- gene-YLR229C_CBS6412 rna-NM_001182116.1_CBS6412 cds-NP_013330.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:594163-594738:- gene-YLR229C_CBS6413 rna-NM_001182116.1_CBS6413 cds-NP_013330.1_CBS6413 99.4 100.0 Mismatch 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:588823-589398:- gene-YLR229C_CENPK1137D rna-NM_001182116.1_CENPK1137D cds-NP_013330.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:551955-552530:- gene-YLR229C_EthanolRed rna-NM_001182116.1_EthanolRed cds-NP_013330.1_EthanolRed 99.4 100.0 Mismatch 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:580880-581455:- gene-YLR229C_FaliES1 rna-NM_001182116.1_FaliES1 cds-NP_013330.1_FaliES1 99.4 100.0 Mismatch 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000227.1:671-1246:+ gene-YLR229C_JAY291 rna-NM_001182116.1_JAY291 cds-NP_013330.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:593518-594093:- gene-YLR229C_MUCL30387 rna-NM_001182116.1_MUCL30387 cds-NP_013330.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:597638-598213:- gene-YLR229C_MUCL30388 rna-NM_001182116.1_MUCL30388 cds-NP_013330.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:594849-595424:- gene-YLR229C_MUCL39482 rna-NM_001182116.1_MUCL39482 cds-NP_013330.1_MUCL39482 99.4 100.0 Mismatch 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:589658-590233:- gene-YLR229C_MUCL42920 rna-NM_001182116.1_MUCL42920 cds-NP_013330.1_MUCL42920 99.8 100.0 Mismatch 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:604186-604761:- gene-YLR229C_NCIM3186 rna-NM_001182116.1_NCIM3186 cds-NP_013330.1_NCIM3186 99.8 100.0 Mismatch 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:581838-582413:- gene-YLR229C_NCYC1407 rna-NM_001182116.1_NCYC1407 cds-NP_013330.1_NCYC1407 99.4 100.0 Mismatch 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:585600-586175:- gene-YLR229C_PE2H3 rna-NM_001182116.1_PE2H3 cds-NP_013330.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:585344-585919:- gene-YLR229C_PE2H4 rna-NM_001182116.1_PE2H4 cds-NP_013330.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:604212-604787:- gene-YLR229C_S288C rna-NM_001182116.1_S288C cds-NP_013330.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:77686-78261:+ gene-YLR229C_SA1 rna-NM_001182116.1_SA1 cds-NP_013330.1_SA1 99.8 100.0 Mismatch 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:583380-583955:- gene-YLR229C_ThermosaccDry rna-NM_001182116.1_ThermosaccDry cds-NP_013330.1_ThermosaccDry 99.4 100.0 Mismatch 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:594714-595289:- gene-YLR229C_VR1 rna-NM_001182116.1_VR1 cds-NP_013330.1_VR1 99.8 100.0 Mismatch 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:107668-108243:- gene-YLR229C_ZTW1 rna-NM_001182116.1_ZTW1 cds-NP_013330.1_ZTW1 99.4 100.0 Mismatch 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:568833-569408:- gene-YLR229C_Sparadoxus rna-NM_001182116.1_Sparadoxus cds-NP_013330.1_Sparadoxus 96.0 100.0 Verified 1 1 1 False True False False False

Additional files