Gene name: CDC40
Reference locus (S288C): YDR364C
Gene biotype: protein_coding
Description: Pre-mRNA-processing factor 17; Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression, particularly at the G1/S phase transition; required for DNA synthesis during mitosis and meiosis; has WD repeats; thermosensitivity of the cdc40 null mutant is functionally complemented by a chimeric construct containing the N-terminal 156 amino acids of yeast Cdc40p fused to the C-terminal two thirds (297 amino acids) of human CDC40
Top 10 interactors (score): PRP45 (0.999); PRP18 (0.999); ECM2 (0.999); SLU7 (0.999); PRP2 (0.999); CWC22 (0.999); SYF2 (0.999); CWC15 (0.999); PRP19 (0.999); PRP46 (0.999); SMB1 (0.999); ISY1 (0.999); YJU2 (0.999); BUD31 (0.999); HSH155 (0.999); SYF1 (0.999); PRP22 (0.999); CWC21 (0.999); CEF1 (0.999); CWC25 (0.999)
Homologues (species, bitscore): CDC40 (Homo sapiens, 282.7); Cdc40 (Mus musculus, 283.5); cdc40 (Danio rerio, 288.5); cdc40 (Xenopus tropicalis, 287.3); CG6015 (Drosophila melanogaster, 281.2); prp-17 (Caenorhabditis elegans, 285.8); AT1G10580 (Arabidopsis thaliana, 271.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1148906-1150273:- | gene-YDR364C_AKU4011 | rna-NM_001180672.3_AKU4011 | cds-NP_010652.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:27457-28824:- | gene-YDR364C_BG1 | rna-NM_001180672.3_BG1 | cds-NP_010652.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1179559-1180926:- | gene-YDR364C_Bruggeman | rna-NM_001180672.3_Bruggeman | cds-NP_010652.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1158151-1159518:- | gene-YDR364C_CAT1 | rna-NM_001180672.3_CAT1 | cds-NP_010652.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1143623-1144990:- | gene-YDR364C_CBS1585 | rna-NM_001180672.3_CBS1585 | cds-NP_010652.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1162207-1163574:- | gene-YDR364C_CBS436 | rna-NM_001180672.3_CBS436 | cds-NP_010652.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1139883-1141250:- | gene-YDR364C_CBS6412 | rna-NM_001180672.3_CBS6412 | cds-NP_010652.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1161773-1163140:- | gene-YDR364C_CBS6413 | rna-NM_001180672.3_CBS6413 | cds-NP_010652.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1201488-1202855:- | gene-YDR364C_CENPK1137D | rna-NM_001180672.3_CENPK1137D | cds-NP_010652.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1153311-1154678:- | gene-YDR364C_EthanolRed | rna-NM_001180672.3_EthanolRed | cds-NP_010652.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1156594-1157961:- | gene-YDR364C_FaliES1 | rna-NM_001180672.3_FaliES1 | cds-NP_010652.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000057.1:33113-34480:+ | gene-YDR364C_JAY291 | rna-NM_001180672.3_JAY291 | cds-NP_010652.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1162859-1164226:- | gene-YDR364C_MUCL30387 | rna-NM_001180672.3_MUCL30387 | cds-NP_010652.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1145464-1146831:- | gene-YDR364C_MUCL30388 | rna-NM_001180672.3_MUCL30388 | cds-NP_010652.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1135157-1136524:- | gene-YDR364C_MUCL39482 | rna-NM_001180672.3_MUCL39482 | cds-NP_010652.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1077591-1078958:- | gene-YDR364C_MUCL42920 | rna-NM_001180672.3_MUCL42920 | cds-NP_010652.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1202766-1204133:- | gene-YDR364C_NCIM3186 | rna-NM_001180672.3_NCIM3186 | cds-NP_010652.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1148828-1150195:- | gene-YDR364C_NCYC1407 | rna-NM_001180672.3_NCYC1407 | cds-NP_010652.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1159260-1160627:- | gene-YDR364C_PE2H3 | rna-NM_001180672.3_PE2H3 | cds-NP_010652.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1164845-1166212:- | gene-YDR364C_PE2H4 | rna-NM_001180672.3_PE2H4 | cds-NP_010652.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1202843-1204210:- | gene-YDR364C_S288C | rna-NM_001180672.3_S288C | cds-NP_010652.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000072.1:27538-28905:- | gene-YDR364C_SA1 | rna-NM_001180672.3_SA1 | cds-NP_010652.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1160875-1162242:- | gene-YDR364C_ThermosaccDry | rna-NM_001180672.3_ThermosaccDry | cds-NP_010652.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:588224-589591:- | gene-YDR364C_VR1 | rna-NM_001180672.3_VR1 | cds-NP_010652.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:203706-205073:- | gene-YDR364C_ZTW1 | rna-NM_001180672.3_ZTW1 | cds-NP_010652.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1155331-1156701:- | gene-YDR364C_Sparadoxus | rna-NM_001180672.3_Sparadoxus | cds-NP_010652.3_Sparadoxus | 89.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |