CDC37 (YDR168W)


Gene profile

Gene name: CDC37
Reference locus (S288C): YDR168W
Gene biotype: protein_coding

Description: Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding; Belongs to the CDC37 family

Top 10 interactors (score): HSP82 (0.999); HSC82 (0.999); STI1 (0.997); AHA1 (0.984); SGT1 (0.976); SBA1 (0.971); HCH1 (0.942); CDC28 (0.931); STE11 (0.93); CPR6 (0.908); CNS1 (0.903); PPT1 (0.881); CPR7 (0.875); YDJ1 (0.867); MPS1 (0.863); CAK1 (0.857); KIN28 (0.822); HSF1 (0.817); SSE1 (0.816); TAH1 (0.805)

Homologues (species, bitscore): Cdc37 (Mus musculus, 50.1); Cdc37 (Drosophila melanogaster, 56.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:761624-763144:+ gene-YDR168W_AKU4011 rna-NM_001180475.1_AKU4011 cds-NP_010452.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:363611-365131:- gene-YDR168W_BG1 rna-NM_001180475.1_BG1 cds-NP_010452.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:793121-794641:+ gene-YDR168W_Bruggeman rna-NM_001180475.1_Bruggeman cds-NP_010452.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:780396-781916:+ gene-YDR168W_CAT1 rna-NM_001180475.1_CAT1 cds-NP_010452.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:751992-753512:+ gene-YDR168W_CBS1585 rna-NM_001180475.1_CBS1585 cds-NP_010452.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:778184-779704:+ gene-YDR168W_CBS436 rna-NM_001180475.1_CBS436 cds-NP_010452.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:747442-748962:+ gene-YDR168W_CBS6412 rna-NM_001180475.1_CBS6412 cds-NP_010452.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:775890-777410:+ gene-YDR168W_CBS6413 rna-NM_001180475.1_CBS6413 cds-NP_010452.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:790990-792510:+ gene-YDR168W_CENPK1137D rna-NM_001180475.1_CENPK1137D cds-NP_010452.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:761450-762970:+ gene-YDR168W_EthanolRed rna-NM_001180475.1_EthanolRed cds-NP_010452.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:769662-771182:+ gene-YDR168W_FaliES1 rna-NM_001180475.1_FaliES1 cds-NP_010452.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000119.1:11080-12600:- gene-YDR168W_JAY291 rna-NM_001180475.1_JAY291 cds-NP_010452.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:778499-780019:+ gene-YDR168W_MUCL30387 rna-NM_001180475.1_MUCL30387 cds-NP_010452.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:767009-768529:+ gene-YDR168W_MUCL30388 rna-NM_001180475.1_MUCL30388 cds-NP_010452.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:753420-754940:+ gene-YDR168W_MUCL39482 rna-NM_001180475.1_MUCL39482 cds-NP_010452.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:691243-692763:+ gene-YDR168W_MUCL42920 rna-NM_001180475.1_MUCL42920 cds-NP_010452.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:790251-791771:+ gene-YDR168W_NCIM3186 rna-NM_001180475.1_NCIM3186 cds-NP_010452.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:752823-754343:+ gene-YDR168W_NCYC1407 rna-NM_001180475.1_NCYC1407 cds-NP_010452.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:772016-773536:+ gene-YDR168W_PE2H3 rna-NM_001180475.1_PE2H3 cds-NP_010452.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:771321-772841:+ gene-YDR168W_PE2H4 rna-NM_001180475.1_PE2H4 cds-NP_010452.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:790328-791848:+ gene-YDR168W_S288C rna-NM_001180475.1_S288C cds-NP_010452.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:137527-139047:+ gene-YDR168W_SA1 rna-NM_001180475.1_SA1 cds-NP_010452.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:767797-769317:+ gene-YDR168W_ThermosaccDry rna-NM_001180475.1_ThermosaccDry cds-NP_010452.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:782785-784305:+ gene-YDR168W_VR1 rna-NM_001180475.1_VR1 cds-NP_010452.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:30547-32067:+ gene-YDR168W_ZTW1 rna-NM_001180475.1_ZTW1 cds-NP_010452.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:773995-775515:+ gene-YDR168W_Sparadoxus rna-NM_001180475.1_Sparadoxus cds-NP_010452.1_Sparadoxus 90.2 100.0 Verified 1 1 1 False True False False False

Additional files