CDC36 (YDL165W)


Gene profile

Gene name: CDC36
Reference locus (S288C): YDL165W
Gene biotype: protein_coding

Description: General negative regulator of transcription subunit 2; Component of the CCR4-NOT core complex, involved in mRNA decapping; this complex has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs through deadenylation; basal transcription factor

Top 10 interactors (score): CAF40 (0.999); NOT5 (0.999); POP2 (0.999); NOT3 (0.999); CCR4 (0.999); CDC39 (0.999); MOT2 (0.999); CAF130 (0.989); MTR4 (0.965); CAF16 (0.958); DHH1 (0.942); BTT1 (0.936); SKI6 (0.928); RRP42 (0.919); XRN1 (0.918); CAF4 (0.824); CCT4 (0.809); NGL1 (0.78); PAT1 (0.775); RRP15 (0.775)

Homologues (species, bitscore): CNOT2 (Homo sapiens, 87.4); cnot2 (Danio rerio, 87.0); cnot2 (Xenopus tropicalis, 86.7); Rga (Drosophila melanogaster, 72.4); ntl-2 (Caenorhabditis elegans, 67.0); AT1G07705 (Arabidopsis thaliana, 84.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:148706-149281:+ gene-YDL165W_AKU4011 rna-NM_001180225.1_AKU4011 cds-NP_010116.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:400448-401023:- gene-YDL165W_BG1 rna-NM_001180225.1_BG1 cds-NP_010116.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:164772-165347:+ gene-YDL165W_Bruggeman rna-NM_001180225.1_Bruggeman cds-NP_010116.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:163078-163653:+ gene-YDL165W_CAT1 rna-NM_001180225.1_CAT1 cds-NP_010116.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:146742-147317:+ gene-YDL165W_CBS1585 rna-NM_001180225.1_CBS1585 cds-NP_010116.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:163703-164278:+ gene-YDL165W_CBS436 rna-NM_001180225.1_CBS436 cds-NP_010116.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:146357-146932:+ gene-YDL165W_CBS6412 rna-NM_001180225.1_CBS6412 cds-NP_010116.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:165168-165743:+ gene-YDL165W_CBS6413 rna-NM_001180225.1_CBS6413 cds-NP_010116.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:162965-163540:+ gene-YDL165W_CENPK1137D rna-NM_001180225.1_CENPK1137D cds-NP_010116.1_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:160168-160743:+ gene-YDL165W_EthanolRed rna-NM_001180225.1_EthanolRed cds-NP_010116.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:165494-166069:+ gene-YDL165W_FaliES1 rna-NM_001180225.1_FaliES1 cds-NP_010116.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000032.1:53494-54069:- gene-YDL165W_JAY291 rna-NM_001180225.1_JAY291 cds-NP_010116.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:163068-163643:+ gene-YDL165W_MUCL30387 rna-NM_001180225.1_MUCL30387 cds-NP_010116.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:154717-155292:+ gene-YDL165W_MUCL30388 rna-NM_001180225.1_MUCL30388 cds-NP_010116.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:147885-148460:+ gene-YDL165W_MUCL39482 rna-NM_001180225.1_MUCL39482 cds-NP_010116.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000307.1:20901-21476:- gene-YDL165W_MUCL42920 rna-NM_001180225.1_MUCL42920 cds-NP_010116.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:164213-164788:+ gene-YDL165W_NCIM3186 rna-NM_001180225.1_NCIM3186 cds-NP_010116.1_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:147825-148400:+ gene-YDL165W_NCYC1407 rna-NM_001180225.1_NCYC1407 cds-NP_010116.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:155070-155645:+ gene-YDL165W_PE2H3 rna-NM_001180225.1_PE2H3 cds-NP_010116.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:155074-155649:+ gene-YDL165W_PE2H4 rna-NM_001180225.1_PE2H4 cds-NP_010116.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:164290-164865:+ gene-YDL165W_S288C rna-NM_001180225.1_S288C cds-NP_010116.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000043.1:29843-30418:+ gene-YDL165W_SA1 rna-NM_001180225.1_SA1 cds-NP_010116.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:165254-165829:+ gene-YDL165W_ThermosaccDry rna-NM_001180225.1_ThermosaccDry cds-NP_010116.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:165841-166416:+ gene-YDL165W_VR1 rna-NM_001180225.1_VR1 cds-NP_010116.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:163385-163960:+ gene-YDL165W_ZTW1 rna-NM_001180225.1_ZTW1 cds-NP_010116.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:165493-166068:+ gene-YDL165W_Sparadoxus rna-NM_001180225.1_Sparadoxus cds-NP_010116.1_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files