Gene name: CDC33
Reference locus (S288C): YOL139C
Gene biotype: protein_coding
Description: mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p); protein abundance increases in response to DNA replication stress; mutants are defective for adhesion and pseudohyphal growth; human homolog EIF4E can complement yeast cdc33 null mutant
Top 10 interactors (score): TIF4631 (0.999); TIF4632 (0.999); CAF20 (0.999); EAP1 (0.999); TIF1 (0.999); PAB1 (0.999); TIF2 (0.999); TIF3 (0.999); PRT1 (0.999); DED1 (0.998); DHH1 (0.998); SUI2 (0.998); STO1 (0.998); RPG1 (0.995); SUI3 (0.993); SUI1 (0.991); SCD6 (0.99); CBC2 (0.989); XRN1 (0.985); GCD11 (0.98)
Homologues (species, bitscore): EIF4E1B (Homo sapiens, 125.9); Eif4e (Mus musculus, 127.9); eif4e1c (Danio rerio, 141.7); eif4e (Xenopus tropicalis, 127.9); eIF-4E (Drosophila melanogaster, 144.1); ife-3 (Caenorhabditis elegans, 127.1); EIF4E (Arabidopsis thaliana, 120.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:49044-49685:- | gene-YOL139C_AKU4011 | rna-NM_001183393.1_AKU4011 | cds-NP_014502.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:14662-15303:- | gene-YOL139C_BG1 | rna-NM_001183393.1_BG1 | cds-NP_014502.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:50321-50962:- | gene-YOL139C_Bruggeman | rna-NM_001183393.1_Bruggeman | cds-NP_014502.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:49276-49917:- | gene-YOL139C_CAT1 | rna-NM_001183393.1_CAT1 | cds-NP_014502.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:43518-44159:- | gene-YOL139C_CBS1585 | rna-NM_001183393.1_CBS1585 | cds-NP_014502.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:49361-50002:- | gene-YOL139C_CBS436 | rna-NM_001183393.1_CBS436 | cds-NP_014502.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:43384-44025:- | gene-YOL139C_CBS6412 | rna-NM_001183393.1_CBS6412 | cds-NP_014502.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:49852-50493:- | gene-YOL139C_CBS6413 | rna-NM_001183393.1_CBS6413 | cds-NP_014502.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:60276-60917:- | gene-YOL139C_CENPK1137D | rna-NM_001183393.1_CENPK1137D | cds-NP_014502.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:47295-47936:- | gene-YOL139C_EthanolRed | rna-NM_001183393.1_EthanolRed | cds-NP_014502.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:49324-49965:- | gene-YOL139C_FaliES1 | rna-NM_001183393.1_FaliES1 | cds-NP_014502.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000329.1:32595-33236:+ | gene-YOL139C_JAY291 | rna-NM_001183393.1_JAY291 | cds-NP_014502.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:54961-55602:- | gene-YOL139C_MUCL30387 | rna-NM_001183393.1_MUCL30387 | cds-NP_014502.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:57952-58593:- | gene-YOL139C_MUCL30388 | rna-NM_001183393.1_MUCL30388 | cds-NP_014502.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:51438-52079:- | gene-YOL139C_MUCL39482 | rna-NM_001183393.1_MUCL39482 | cds-NP_014502.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:67341-67982:- | gene-YOL139C_MUCL42920 | rna-NM_001183393.1_MUCL42920 | cds-NP_014502.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:60272-60913:- | gene-YOL139C_NCIM3186 | rna-NM_001183393.1_NCIM3186 | cds-NP_014502.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:57494-58135:- | gene-YOL139C_NCYC1407 | rna-NM_001183393.1_NCYC1407 | cds-NP_014502.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:35914-36555:- | gene-YOL139C_PE2H3 | rna-NM_001183393.1_PE2H3 | cds-NP_014502.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:52862-53503:- | gene-YOL139C_PE2H4 | rna-NM_001183393.1_PE2H4 | cds-NP_014502.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:60383-61024:- | gene-YOL139C_S288C | rna-NM_001183393.1_S288C | cds-NP_014502.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:33811-34452:- | gene-YOL139C_SA1 | rna-NM_001183393.1_SA1 | cds-NP_014502.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:48462-49103:- | gene-YOL139C_ThermosaccDry | rna-NM_001183393.1_ThermosaccDry | cds-NP_014502.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:49112-49753:- | gene-YOL139C_VR1 | rna-NM_001183393.1_VR1 | cds-NP_014502.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:48216-48857:- | gene-YOL139C_ZTW1 | rna-NM_001183393.1_ZTW1 | cds-NP_014502.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:50682-51323:- | gene-YOL139C_Sparadoxus | rna-NM_001183393.1_Sparadoxus | cds-NP_014502.1_Sparadoxus | 96.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |