Gene name: CDC24
Reference locus (S288C): YAL041W
Gene biotype: protein_coding
Description: Cell division control protein 24; Guanine nucleotide exchange factor (GEF) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing; relocalizes from nucleus to cytoplasm upon DNA replication stress; thermosensitivity of the cdc24-4 mutant in the presence of sorbitol is functionally complemented by human CDC42
Top 10 interactors (score): RSR1 (0.999); BOI2 (0.999); CDC42 (0.999); FAR1 (0.999); BEM1 (0.999); RGA1 (0.998); RGA2 (0.998); CLA4 (0.993); STE20 (0.981); STE4 (0.973); SHO1 (0.958); RAS2 (0.954); BNI1 (0.949); RHO1 (0.949); ACT1 (0.948); BEM3 (0.931); STE5 (0.929); RAS1 (0.927); STE11 (0.922); GIC2 (0.91)
Homologues (species, bitscore): SPATA13 (Homo sapiens, 94.7); Prex2 (Mus musculus, 93.2); arhgef4 (Danio rerio, 97.4); arhgef4 (Xenopus tropicalis, 89.7); GEFmeso (Drosophila melanogaster, 82.4); vav-1 (Caenorhabditis elegans, 62.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:47983-50547:+ | gene-YAL041W_AKU4011 | rna-NM_001178186.1_AKU4011 | cds-NP_009359.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:35052-37616:+ | gene-YAL041W_BG1 | rna-NM_001178186.1_BG1 | cds-NP_009359.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:62441-65005:+ | gene-YAL041W_Bruggeman | rna-NM_001178186.1_Bruggeman | cds-NP_009359.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:49202-51766:+ | gene-YAL041W_CAT1 | rna-NM_001178186.1_CAT1 | cds-NP_009359.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:61004-63568:+ | gene-YAL041W_CBS1585 | rna-NM_001178186.1_CBS1585 | cds-NP_009359.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:61246-63810:+ | gene-YAL041W_CBS436 | rna-NM_001178186.1_CBS436 | cds-NP_009359.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:47149-49713:+ | gene-YAL041W_CBS6412 | rna-NM_001178186.1_CBS6412 | cds-NP_009359.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:59267-61831:+ | gene-YAL041W_CBS6413 | rna-NM_001178186.1_CBS6413 | cds-NP_009359.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:62896-65460:+ | gene-YAL041W_CENPK1137D | rna-NM_001178186.1_CENPK1137D | cds-NP_009359.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:49397-51961:+ | gene-YAL041W_EthanolRed | rna-NM_001178186.1_EthanolRed | cds-NP_009359.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:63339-65903:+ | gene-YAL041W_FaliES1 | rna-NM_001178186.1_FaliES1 | cds-NP_009359.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:35291-37855:+ | gene-YAL041W_JAY291 | rna-NM_001178186.1_JAY291 | cds-NP_009359.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:63947-66511:+ | gene-YAL041W_MUCL30387 | rna-NM_001178186.1_MUCL30387 | cds-NP_009359.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:60492-63056:+ | gene-YAL041W_MUCL30388 | rna-NM_001178186.1_MUCL30388 | cds-NP_009359.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:59808-62372:+ | gene-YAL041W_MUCL39482 | rna-NM_001178186.1_MUCL39482 | cds-NP_009359.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:62150-64714:+ | gene-YAL041W_MUCL42920 | rna-NM_001178186.1_MUCL42920 | cds-NP_009359.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:62717-65281:+ | gene-YAL041W_NCIM3186 | rna-NM_001178186.1_NCIM3186 | cds-NP_009359.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:47673-50237:+ | gene-YAL041W_NCYC1407 | rna-NM_001178186.1_NCYC1407 | cds-NP_009359.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:49555-52119:+ | gene-YAL041W_PE2H3 | rna-NM_001178186.1_PE2H3 | cds-NP_009359.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:49274-51838:+ | gene-YAL041W_PE2H4 | rna-NM_001178186.1_PE2H4 | cds-NP_009359.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:62840-65404:+ | gene-YAL041W_S288C | rna-NM_001178186.1_S288C | cds-NP_009359.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000084.1:37449-40013:+ | gene-YAL041W_SA1 | rna-NM_001178186.1_SA1 | cds-NP_009359.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:63549-66113:+ | gene-YAL041W_ThermosaccDry | rna-NM_001178186.1_ThermosaccDry | cds-NP_009359.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:64816-67380:+ | gene-YAL041W_VR1 | rna-NM_001178186.1_VR1 | cds-NP_009359.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:35358-37922:+ | gene-YAL041W_ZTW1 | rna-NM_001178186.1_ZTW1 | cds-NP_009359.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:53028-55592:+ | gene-YAL041W_Sparadoxus | rna-NM_001178186.1_Sparadoxus | cds-NP_009359.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |