CDC23 (YHR166C)


Gene profile

Gene name: CDC23
Reference locus (S288C): YHR166C
Gene biotype: protein_coding

Description: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition

Top 10 interactors (score): APC9 (0.999); APC4 (0.999); APC5 (0.999); CDC16 (0.999); SWM1 (0.999); APC11 (0.999); DOC1 (0.999); APC1 (0.999); CDC27 (0.999); MND2 (0.999); CDC26 (0.999); CDH1 (0.999); APC2 (0.999); CDC20 (0.999); MAD2 (0.998); BUB3 (0.998); MAD3 (0.994); BUB1 (0.99); CLB2 (0.987); AMA1 (0.985)

Homologues (species, bitscore): CDC23 (Homo sapiens, 250.8); Cdc23 (Mus musculus, 248.8); cdc23 (Danio rerio, 236.9); cdc23 (Xenopus tropicalis, 241.5); Cdc23 (Drosophila melanogaster, 253.8); mat-3 (Caenorhabditis elegans, 171.8); APC8 (Arabidopsis thaliana, 284.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:424264-426144:- gene-YHR166C_AKU4011 rna-NM_001179297.1_AKU4011 cds-NP_012036.1_AKU4011 99.4 100.0 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:91594-93474:+ gene-YHR166C_BG1 rna-NM_001179297.1_BG1 cds-NP_012036.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:431505-433385:- gene-YHR166C_Bruggeman rna-NM_001179297.1_Bruggeman cds-NP_012036.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:426910-428790:- gene-YHR166C_CAT1 rna-NM_001179297.1_CAT1 cds-NP_012036.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:423720-425600:- gene-YHR166C_CBS1585 rna-NM_001179297.1_CBS1585 cds-NP_012036.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:421163-423043:- gene-YHR166C_CBS436 rna-NM_001179297.1_CBS436 cds-NP_012036.1_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:424174-426054:- gene-YHR166C_CBS6412 rna-NM_001179297.1_CBS6412 cds-NP_012036.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:424601-426481:- gene-YHR166C_CBS6413 rna-NM_001179297.1_CBS6413 cds-NP_012036.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:430341-432221:- gene-YHR166C_CENPK1137D rna-NM_001179297.1_CENPK1137D cds-NP_012036.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:482814-484694:- gene-YHR166C_EthanolRed rna-NM_001179297.1_EthanolRed cds-NP_012036.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:425257-427137:- gene-YHR166C_FaliES1 rna-NM_001179297.1_FaliES1 cds-NP_012036.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000017.1:12706-14585:+ gene-YHR166C_JAY291 rna-NM_001179297.1_JAY291 cds-NP_012036.1_JAY291 99.9 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:432576-434456:- gene-YHR166C_MUCL30387 rna-NM_001179297.1_MUCL30387 cds-NP_012036.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:432015-433895:- gene-YHR166C_MUCL30388 rna-NM_001179297.1_MUCL30388 cds-NP_012036.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:423631-425511:- gene-YHR166C_MUCL39482 rna-NM_001179297.1_MUCL39482 cds-NP_012036.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:430238-432118:- gene-YHR166C_MUCL42920 rna-NM_001179297.1_MUCL42920 cds-NP_012036.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:437052-438932:- gene-YHR166C_NCIM3186 rna-NM_001179297.1_NCIM3186 cds-NP_012036.1_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:426090-427970:- gene-YHR166C_NCYC1407 rna-NM_001179297.1_NCYC1407 cds-NP_012036.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:425232-427112:- gene-YHR166C_PE2H3 rna-NM_001179297.1_PE2H3 cds-NP_012036.1_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:432659-434539:- gene-YHR166C_PE2H4 rna-NM_001179297.1_PE2H4 cds-NP_012036.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:437170-439050:- gene-YHR166C_S288C rna-NM_001179297.1_S288C cds-NP_012036.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000070.1:12765-14645:+ gene-YHR166C_SA1 rna-NM_001179297.1_SA1 cds-NP_012036.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:426340-428220:- gene-YHR166C_ThermosaccDry rna-NM_001179297.1_ThermosaccDry cds-NP_012036.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:434158-436038:- gene-YHR166C_VR1 rna-NM_001179297.1_VR1 cds-NP_012036.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:416580-418460:- gene-YHR166C_ZTW1 rna-NM_001179297.1_ZTW1 cds-NP_012036.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:422673-424553:- gene-YHR166C_Sparadoxus rna-NM_001179297.1_Sparadoxus cds-NP_012036.1_Sparadoxus 92.1 100.0 Verified 1 1 1 False True False False False

Additional files