Gene name: CDC21
Reference locus (S288C): YOR074C
Gene biotype: protein_coding
Description: Thymidylate synthase; required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S; human homolog TYMSOS can complement yeast cdc21 temperature-sensitive mutant at restrictive temperature
Top 10 interactors (score): DFR1 (0.999); DUT1 (0.999); CDC8 (0.998); DCD1 (0.997); UNG1 (0.986); RNR1 (0.986); POL1 (0.98); CDC9 (0.976); SHM1 (0.974); SHM2 (0.973); GCV1 (0.97); MTD1 (0.967); MET13 (0.967); MIS1 (0.966); MET12 (0.966); ADE3 (0.964); RNR3 (0.963); RNR4 (0.961); MET7 (0.96); RNR2 (0.958)
Homologues (species, bitscore): TYMS (Homo sapiens, 375.6); Tyms (Mus musculus, 380.9); tyms (Danio rerio, 384.4); tyms (Xenopus tropicalis, 380.6); Ts (Drosophila melanogaster, 412.1); Y110A7A.4 (Caenorhabditis elegans, 357.8); THY-2 (Arabidopsis thaliana, 374.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:451023-451937:- | gene-YOR074C_AKU4011 | rna-NM_001183493.1_AKU4011 | cds-NP_014717.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:127760-128674:+ | gene-YOR074C_BG1 | rna-NM_001183493.1_BG1 | cds-NP_014717.2_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:453739-454653:- | gene-YOR074C_Bruggeman | rna-NM_001183493.1_Bruggeman | cds-NP_014717.2_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:452508-453422:- | gene-YOR074C_CAT1 | rna-NM_001183493.1_CAT1 | cds-NP_014717.2_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:445742-446656:- | gene-YOR074C_CBS1585 | rna-NM_001183493.1_CBS1585 | cds-NP_014717.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:450539-451453:- | gene-YOR074C_CBS436 | rna-NM_001183493.1_CBS436 | cds-NP_014717.2_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:445032-445946:- | gene-YOR074C_CBS6412 | rna-NM_001183493.1_CBS6412 | cds-NP_014717.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:452349-453263:- | gene-YOR074C_CBS6413 | rna-NM_001183493.1_CBS6413 | cds-NP_014717.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:466671-467585:- | gene-YOR074C_CENPK1137D | rna-NM_001183493.1_CENPK1137D | cds-NP_014717.2_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:447734-448648:- | gene-YOR074C_EthanolRed | rna-NM_001183493.1_EthanolRed | cds-NP_014717.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:451063-451977:- | gene-YOR074C_FaliES1 | rna-NM_001183493.1_FaliES1 | cds-NP_014717.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000231.1:20010-20924:+ | gene-YOR074C_JAY291 | rna-NM_001183493.1_JAY291 | cds-NP_014717.2_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:458522-459436:- | gene-YOR074C_MUCL30387 | rna-NM_001183493.1_MUCL30387 | cds-NP_014717.2_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:463179-464093:- | gene-YOR074C_MUCL30388 | rna-NM_001183493.1_MUCL30388 | cds-NP_014717.2_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:453457-454371:- | gene-YOR074C_MUCL39482 | rna-NM_001183493.1_MUCL39482 | cds-NP_014717.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:469000-469914:- | gene-YOR074C_MUCL42920 | rna-NM_001183493.1_MUCL42920 | cds-NP_014717.2_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:466564-467478:- | gene-YOR074C_NCIM3186 | rna-NM_001183493.1_NCIM3186 | cds-NP_014717.2_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:460129-461043:- | gene-YOR074C_NCYC1407 | rna-NM_001183493.1_NCYC1407 | cds-NP_014717.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:458775-459689:- | gene-YOR074C_PE2H3 | rna-NM_001183493.1_PE2H3 | cds-NP_014717.2_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:469151-470065:- | gene-YOR074C_PE2H4 | rna-NM_001183493.1_PE2H4 | cds-NP_014717.2_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:466675-467589:- | gene-YOR074C_S288C | rna-NM_001183493.1_S288C | cds-NP_014717.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000091.1:20038-20952:+ | gene-YOR074C_SA1 | rna-NM_001183493.1_SA1 | cds-NP_014717.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:450219-451133:- | gene-YOR074C_ThermosaccDry | rna-NM_001183493.1_ThermosaccDry | cds-NP_014717.2_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:451713-452627:- | gene-YOR074C_VR1 | rna-NM_001183493.1_VR1 | cds-NP_014717.2_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:184216-185130:- | gene-YOR074C_ZTW1 | rna-NM_001183493.1_ZTW1 | cds-NP_014717.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:455850-456764:- | gene-YOR074C_Sparadoxus | rna-NM_001183493.1_Sparadoxus | cds-NP_014717.2_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |