CDC20 (YGL116W)


Gene profile

Gene name: CDC20
Reference locus (S288C): YGL116W
Gene biotype: protein_coding

Description: Ubiquitin-protein transferase activating protein cdc20; Activator of anaphase-promoting complex/cyclosome (APC/C); APC/C is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; cell-cycle regulated; potential Cdc28p substrate; relative distribution to the nucleus increases upon DNA replication stress; Belongs to the WD repeat CDC20/Fizzy family

Top 10 interactors (score): BUB3 (0.999); CDC27 (0.999); CDC23 (0.999); PDS1 (0.999); BUB1 (0.999); MAD2 (0.999); CDC16 (0.999); MAD3 (0.999); APC11 (0.998); CLB2 (0.998); APC2 (0.998); APC1 (0.998); CDC5 (0.997); DOC1 (0.996); CLB5 (0.996); CDC28 (0.995); ESP1 (0.994); CDC14 (0.989); CLB1 (0.984); APC4 (0.983)

Homologues (species, bitscore): CDC20 (Homo sapiens, 260.8); Cdc20 (Mus musculus, 258.5); cdc20 (Danio rerio, 282.7); cdc20 (Xenopus tropicalis, 252.7); fzy (Drosophila melanogaster, 249.6); fzr-1 (Caenorhabditis elegans, 231.5); CDC20.1 (Arabidopsis thaliana, 275.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:293141-294973:+ gene-YGL116W_AKU4011 rna-NM_001180981.1_AKU4011 cds-NP_011399.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:110774-112606:- gene-YGL116W_BG1 rna-NM_001180981.1_BG1 cds-NP_011399.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:295299-297131:+ gene-YGL116W_Bruggeman rna-NM_001180981.1_Bruggeman cds-NP_011399.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:290820-292652:+ gene-YGL116W_CAT1 rna-NM_001180981.1_CAT1 cds-NP_011399.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:296466-298298:+ gene-YGL116W_CBS1585 rna-NM_001180981.1_CBS1585 cds-NP_011399.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:290770-292602:+ gene-YGL116W_CBS436 rna-NM_001180981.1_CBS436 cds-NP_011399.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:281159-282991:+ gene-YGL116W_CBS6412 rna-NM_001180981.1_CBS6412 cds-NP_011399.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:290758-292590:+ gene-YGL116W_CBS6413 rna-NM_001180981.1_CBS6413 cds-NP_011399.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:289996-291828:+ gene-YGL116W_CENPK1137D rna-NM_001180981.1_CENPK1137D cds-NP_011399.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:282208-284040:+ gene-YGL116W_EthanolRed rna-NM_001180981.1_EthanolRed cds-NP_011399.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:284763-286595:+ gene-YGL116W_FaliES1 rna-NM_001180981.1_FaliES1 cds-NP_011399.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000046.1:15546-17378:- gene-YGL116W_JAY291 rna-NM_001180981.1_JAY291 cds-NP_011399.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:292269-294101:+ gene-YGL116W_MUCL30387 rna-NM_001180981.1_MUCL30387 cds-NP_011399.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:295361-297193:+ gene-YGL116W_MUCL30388 rna-NM_001180981.1_MUCL30388 cds-NP_011399.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:292979-294811:+ gene-YGL116W_MUCL39482 rna-NM_001180981.1_MUCL39482 cds-NP_011399.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:296259-298091:+ gene-YGL116W_MUCL42920 rna-NM_001180981.1_MUCL42920 cds-NP_011399.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:289809-291641:+ gene-YGL116W_NCIM3186 rna-NM_001180981.1_NCIM3186 cds-NP_011399.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:284469-286301:+ gene-YGL116W_NCYC1407 rna-NM_001180981.1_NCYC1407 cds-NP_011399.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:285853-287685:+ gene-YGL116W_PE2H3 rna-NM_001180981.1_PE2H3 cds-NP_011399.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:290851-292683:+ gene-YGL116W_PE2H4 rna-NM_001180981.1_PE2H4 cds-NP_011399.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:289809-291641:+ gene-YGL116W_S288C rna-NM_001180981.1_S288C cds-NP_011399.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000064.1:34602-36434:+ gene-YGL116W_SA1 rna-NM_001180981.1_SA1 cds-NP_011399.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:284975-286807:+ gene-YGL116W_ThermosaccDry rna-NM_001180981.1_ThermosaccDry cds-NP_011399.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:394576-396408:+ gene-YGL116W_VR1 rna-NM_001180981.1_VR1 cds-NP_011399.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:282377-284209:+ gene-YGL116W_ZTW1 rna-NM_001180981.1_ZTW1 cds-NP_011399.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:288747-290582:+ gene-YGL116W_Sparadoxus rna-NM_001180981.1_Sparadoxus cds-NP_011399.1_Sparadoxus 91.7 100.0 Verified 1 1 1 False True False False False

Additional files