Gene name: CDC16
Reference locus (S288C): YKL022C
Gene biotype: protein_coding
Description: Subunit of the anaphase-promoting complex/cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): APC11 (0.999); DOC1 (0.999); MND2 (0.999); APC9 (0.999); CDC27 (0.999); APC1 (0.999); APC4 (0.999); CDC26 (0.999); APC5 (0.999); MAD2 (0.999); CDH1 (0.999); CDC23 (0.999); SWM1 (0.999); CDC20 (0.999); APC2 (0.999); AMA1 (0.998); UBC11 (0.993); MAD3 (0.992); BUB1 (0.987); CDC5 (0.978)
Homologues (species, bitscore): CDC16 (Homo sapiens, 302.4); Cdc16 (Mus musculus, 305.1); cdc16 (Danio rerio, 300.8); cdc16 (Xenopus tropicalis, 191.0); Cdc16 (Drosophila melanogaster, 196.1); emb-27 (Caenorhabditis elegans, 94.0); APC6 (Arabidopsis thaliana, 295.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:380744-383266:- | gene-YKL022C_AKU4011 | rna-NM_001179588.1_AKU4011 | cds-NP_012903.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:260639-263161:+ | gene-YKL022C_BG1 | rna-NM_001179588.1_BG1 | cds-NP_012903.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:402440-404968:- | gene-YKL022C_Bruggeman | rna-NM_001179588.1_Bruggeman | cds-NP_012903.1_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:397554-400076:- | gene-YKL022C_CAT1 | rna-NM_001179588.1_CAT1 | cds-NP_012903.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:393463-395985:- | gene-YKL022C_CBS1585 | rna-NM_001179588.1_CBS1585 | cds-NP_012903.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:392324-394846:- | gene-YKL022C_CBS436 | rna-NM_001179588.1_CBS436 | cds-NP_012903.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:377619-380141:- | gene-YKL022C_CBS6412 | rna-NM_001179588.1_CBS6412 | cds-NP_012903.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:393318-395840:- | gene-YKL022C_CBS6413 | rna-NM_001179588.1_CBS6413 | cds-NP_012903.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:394403-396925:- | gene-YKL022C_CENPK1137D | rna-NM_001179588.1_CENPK1137D | cds-NP_012903.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:391240-393762:- | gene-YKL022C_EthanolRed | rna-NM_001179588.1_EthanolRed | cds-NP_012903.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:393330-395852:- | gene-YKL022C_FaliES1 | rna-NM_001179588.1_FaliES1 | cds-NP_012903.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000142.1:35198-37720:+ | gene-YKL022C_JAY291 | rna-NM_001179588.1_JAY291 | cds-NP_012903.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:401755-404283:- | gene-YKL022C_MUCL30387 | rna-NM_001179588.1_MUCL30387 | cds-NP_012903.1_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:397364-399892:- | gene-YKL022C_MUCL30388 | rna-NM_001179588.1_MUCL30388 | cds-NP_012903.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:392780-395302:- | gene-YKL022C_MUCL39482 | rna-NM_001179588.1_MUCL39482 | cds-NP_012903.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:398607-401129:- | gene-YKL022C_MUCL42920 | rna-NM_001179588.1_MUCL42920 | cds-NP_012903.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:394715-397237:- | gene-YKL022C_NCIM3186 | rna-NM_001179588.1_NCIM3186 | cds-NP_012903.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:392972-395494:- | gene-YKL022C_NCYC1407 | rna-NM_001179588.1_NCYC1407 | cds-NP_012903.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:417662-420184:- | gene-YKL022C_PE2H3 | rna-NM_001179588.1_PE2H3 | cds-NP_012903.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:402406-404928:- | gene-YKL022C_PE2H4 | rna-NM_001179588.1_PE2H4 | cds-NP_012903.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:394726-397248:- | gene-YKL022C_S288C | rna-NM_001179588.1_S288C | cds-NP_012903.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:73004-75526:- | gene-YKL022C_SA1 | rna-NM_001179588.1_SA1 | cds-NP_012903.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:393429-395951:- | gene-YKL022C_ThermosaccDry | rna-NM_001179588.1_ThermosaccDry | cds-NP_012903.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:392685-395207:- | gene-YKL022C_VR1 | rna-NM_001179588.1_VR1 | cds-NP_012903.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:391457-393979:- | gene-YKL022C_ZTW1 | rna-NM_001179588.1_ZTW1 | cds-NP_012903.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:416451-418963:- | gene-YKL022C_Sparadoxus | rna-NM_001179588.1_Sparadoxus | cds-NP_012903.1_Sparadoxus | 88.3 | 99.2 | Verified | 1 | 1 | 0 | False | False | False | True | False |