CDC15 (YAR019C)


Gene profile

Gene name: CDC15
Reference locus (S288C): YAR019C
Gene biotype: protein_coding

Description: Cell division control protein 15; Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress

Top 10 interactors (score): TEM1 (0.999); NUD1 (0.999); CDC14 (0.997); MOB1 (0.997); BUB2 (0.996); DBF2 (0.985); LTE1 (0.98); CLB2 (0.975); SPO12 (0.969); BFA1 (0.924); SIC1 (0.921); NET1 (0.92); DBF20 (0.908); HOF1 (0.895); CDC5 (0.886); CDC20 (0.883); ESP1 (0.872); PDS1 (0.87); IQG1 (0.846); MYO1 (0.843)

Homologues (species, bitscore): STK4 (Homo sapiens, 202.2); Stk4 (Mus musculus, 201.1); stk3 (Danio rerio, 199.1); stk3 (Xenopus tropicalis, 199.9); hpo (Drosophila melanogaster, 191.0); cst-1 (Caenorhabditis elegans, 182.6); MAPKKK7 (Arabidopsis thaliana, 224.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:151709-154633:- gene-YAR019C_AKU4011 rna-NM_001178218.2_AKU4011 cds-NP_009411.2_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000193.1:6371-9295:- gene-YAR019C_BG1 rna-NM_001178218.2_BG1 cds-NP_009411.2_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:167727-170651:- gene-YAR019C_Bruggeman rna-NM_001178218.2_Bruggeman cds-NP_009411.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:153349-156273:- gene-YAR019C_CAT1 rna-NM_001178218.2_CAT1 cds-NP_009411.2_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:164409-167333:- gene-YAR019C_CBS1585 rna-NM_001178218.2_CBS1585 cds-NP_009411.2_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:164735-167659:- gene-YAR019C_CBS436 rna-NM_001178218.2_CBS436 cds-NP_009411.2_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:777149-780073:- gene-YAR019C_CBS6412 rna-NM_001178218.2_CBS6412 cds-NP_009411.2_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:162673-165597:- gene-YAR019C_CBS6413 rna-NM_001178218.2_CBS6413 cds-NP_009411.2_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:166187-169111:- gene-YAR019C_CENPK1137D rna-NM_001178218.2_CENPK1137D cds-NP_009411.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:152263-155187:- gene-YAR019C_EthanolRed rna-NM_001178218.2_EthanolRed cds-NP_009411.2_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:167926-170850:- gene-YAR019C_FaliES1 rna-NM_001178218.2_FaliES1 cds-NP_009411.2_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000304.1:6065-8989:- gene-YAR019C_JAY291 rna-NM_001178218.2_JAY291 cds-NP_009411.2_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:168262-171186:- gene-YAR019C_MUCL30387 rna-NM_001178218.2_MUCL30387 cds-NP_009411.2_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:164917-167841:- gene-YAR019C_MUCL30388 rna-NM_001178218.2_MUCL30388 cds-NP_009411.2_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:163661-166585:- gene-YAR019C_MUCL39482 rna-NM_001178218.2_MUCL39482 cds-NP_009411.2_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:166064-168988:- gene-YAR019C_MUCL42920 rna-NM_001178218.2_MUCL42920 cds-NP_009411.2_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:172088-175012:- gene-YAR019C_NCIM3186 rna-NM_001178218.2_NCIM3186 cds-NP_009411.2_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:151073-153997:- gene-YAR019C_NCYC1407 rna-NM_001178218.2_NCYC1407 cds-NP_009411.2_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:159264-162188:- gene-YAR019C_PE2H3 rna-NM_001178218.2_PE2H3 cds-NP_009411.2_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:158983-161907:- gene-YAR019C_PE2H4 rna-NM_001178218.2_PE2H4 cds-NP_009411.2_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:172211-175135:- gene-YAR019C_S288C rna-NM_001178218.2_S288C cds-NP_009411.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000100.1:25013-27937:- gene-YAR019C_SA1 rna-NM_001178218.2_SA1 cds-NP_009411.2_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:166931-169855:- gene-YAR019C_ThermosaccDry rna-NM_001178218.2_ThermosaccDry cds-NP_009411.2_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:171486-174410:- gene-YAR019C_VR1 rna-NM_001178218.2_VR1 cds-NP_009411.2_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:138753-141677:- gene-YAR019C_ZTW1 rna-NM_001178218.2_ZTW1 cds-NP_009411.2_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:156440-159364:- gene-YAR019C_Sparadoxus rna-NM_001178218.2_Sparadoxus cds-NP_009411.2_Sparadoxus 89.5 99.9 Verified 1 1 1 False True False False False

Additional files