CDC13 (YDL220C)


Gene profile

Gene name: CDC13
Reference locus (S288C): YDL220C
Gene biotype: protein_coding

Description: Cell division control protein 13; Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle

Top 10 interactors (score): STN1 (0.999); EST1 (0.999); TEN1 (0.999); POL1 (0.999); RIF2 (0.99); RAD9 (0.989); EXO1 (0.988); YKU80 (0.985); MEC1 (0.978); YKU70 (0.978); EST3 (0.978); RIF1 (0.977); EST2 (0.969); TEL1 (0.968); RAD24 (0.967); PIF1 (0.965); RAP1 (0.959); RAD53 (0.941); CHK1 (0.929); RAD52 (0.91)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:45733-48507:- gene-YDL220C_AKU4011 rna-NM_001180280.1_AKU4011 cds-NP_010061.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000077.1:18560-21334:+ gene-YDL220C_BG1 rna-NM_001180280.1_BG1 cds-NP_010061.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:61414-64188:- gene-YDL220C_Bruggeman rna-NM_001180280.1_Bruggeman cds-NP_010061.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:281262-284036:- gene-YDL220C_CAT1 rna-NM_001180280.1_CAT1 cds-NP_010061.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:44608-47382:- gene-YDL220C_CBS1585 rna-NM_001180280.1_CBS1585 cds-NP_010061.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:259493-262267:- gene-YDL220C_CBS436 rna-NM_001180280.1_CBS436 cds-NP_010061.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:44720-47494:- gene-YDL220C_CBS6412 rna-NM_001180280.1_CBS6412 cds-NP_010061.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:62243-65017:- gene-YDL220C_CBS6413 rna-NM_001180280.1_CBS6413 cds-NP_010061.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:60910-63684:- gene-YDL220C_CENPK1137D rna-NM_001180280.1_CENPK1137D cds-NP_010061.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:58181-60955:- gene-YDL220C_EthanolRed rna-NM_001180280.1_EthanolRed cds-NP_010061.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:62508-65282:- gene-YDL220C_FaliES1 rna-NM_001180280.1_FaliES1 cds-NP_010061.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000213.1:16837-19611:- gene-YDL220C_JAY291 rna-NM_001180280.1_JAY291 cds-NP_010061.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:60362-63136:- gene-YDL220C_MUCL30387 rna-NM_001180280.1_MUCL30387 cds-NP_010061.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:268180-270954:- gene-YDL220C_MUCL30388 rna-NM_001180280.1_MUCL30388 cds-NP_010061.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:45451-48225:- gene-YDL220C_MUCL39482 rna-NM_001180280.1_MUCL39482 cds-NP_010061.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:61511-64285:- gene-YDL220C_MUCL42920 rna-NM_001180280.1_MUCL42920 cds-NP_010061.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:62167-64941:- gene-YDL220C_NCIM3186 rna-NM_001180280.1_NCIM3186 cds-NP_010061.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:45408-48182:- gene-YDL220C_NCYC1407 rna-NM_001180280.1_NCYC1407 cds-NP_010061.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:52450-55224:- gene-YDL220C_PE2H3 rna-NM_001180280.1_PE2H3 cds-NP_010061.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:52460-55234:- gene-YDL220C_PE2H4 rna-NM_001180280.1_PE2H4 cds-NP_010061.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:62244-65018:- gene-YDL220C_S288C rna-NM_001180280.1_S288C cds-NP_010061.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000094.1:16645-19419:- gene-YDL220C_SA1 rna-NM_001180280.1_SA1 cds-NP_010061.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:62263-65037:- gene-YDL220C_ThermosaccDry rna-NM_001180280.1_ThermosaccDry cds-NP_010061.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:63217-65991:- gene-YDL220C_VR1 rna-NM_001180280.1_VR1 cds-NP_010061.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:61431-64205:- gene-YDL220C_ZTW1 rna-NM_001180280.1_ZTW1 cds-NP_010061.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:64841-67609:- gene-YDL220C_Sparadoxus rna-NM_001180280.1_Sparadoxus cds-NP_010061.1_Sparadoxus 85.4 99.2 Verified 1 1 0 False False False True False

Additional files