CDC12 (YHR107C)


Gene profile

Gene name: CDC12
Reference locus (S288C): YHR107C
Gene biotype: protein_coding

Description: Cell division control protein 12; Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells

Top 10 interactors (score): CDC10 (0.998); CDC3 (0.997); CDC11 (0.997); SHS1 (0.996); BUD4 (0.984); GIN4 (0.983); HSL1 (0.969); BNI5 (0.963); AFR1 (0.961); GIC1 (0.949); KCC4 (0.948); GIC2 (0.938); CLA4 (0.934); SPR28 (0.927); SPR3 (0.918); YSW1 (0.904); BNI4 (0.897); SWE1 (0.881); BUD3 (0.88); CDC42 (0.874)

Homologues (species, bitscore): SEPT4 (Homo sapiens, 263.8); Sept7 (Mus musculus, 267.3); sept7b (Danio rerio, 270.0); sept7 (Xenopus tropicalis, 272.3); Sep1 (Drosophila melanogaster, 258.8); unc-59 (Caenorhabditis elegans, 239.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:313733-314956:- gene-YHR107C_AKU4011 rna-NM_001179237.1_AKU4011 cds-NP_011975.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:202953-204176:+ gene-YHR107C_BG1 rna-NM_001179237.1_BG1 cds-NP_011975.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:321027-322250:- gene-YHR107C_Bruggeman rna-NM_001179237.1_Bruggeman cds-NP_011975.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:316168-317391:- gene-YHR107C_CAT1 rna-NM_001179237.1_CAT1 cds-NP_011975.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:312756-313979:- gene-YHR107C_CBS1585 rna-NM_001179237.1_CBS1585 cds-NP_011975.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:310111-311334:- gene-YHR107C_CBS436 rna-NM_001179237.1_CBS436 cds-NP_011975.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:314566-315789:- gene-YHR107C_CBS6412 rna-NM_001179237.1_CBS6412 cds-NP_011975.1_CBS6412 99.4 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:313784-315007:- gene-YHR107C_CBS6413 rna-NM_001179237.1_CBS6413 cds-NP_011975.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:319984-321207:- gene-YHR107C_CENPK1137D rna-NM_001179237.1_CENPK1137D cds-NP_011975.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:372641-373864:- gene-YHR107C_EthanolRed rna-NM_001179237.1_EthanolRed cds-NP_011975.1_EthanolRed 99.5 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:314129-315352:- gene-YHR107C_FaliES1 rna-NM_001179237.1_FaliES1 cds-NP_011975.1_FaliES1 99.5 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000045.1:34708-35931:- gene-YHR107C_JAY291 rna-NM_001179237.1_JAY291 cds-NP_011975.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:320751-321974:- gene-YHR107C_MUCL30387 rna-NM_001179237.1_MUCL30387 cds-NP_011975.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:320405-321628:- gene-YHR107C_MUCL30388 rna-NM_001179237.1_MUCL30388 cds-NP_011975.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:313097-314320:- gene-YHR107C_MUCL39482 rna-NM_001179237.1_MUCL39482 cds-NP_011975.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:319343-320566:- gene-YHR107C_MUCL42920 rna-NM_001179237.1_MUCL42920 cds-NP_011975.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:326695-327918:- gene-YHR107C_NCIM3186 rna-NM_001179237.1_NCIM3186 cds-NP_011975.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:315306-316529:- gene-YHR107C_NCYC1407 rna-NM_001179237.1_NCYC1407 cds-NP_011975.1_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:314744-315967:- gene-YHR107C_PE2H3 rna-NM_001179237.1_PE2H3 cds-NP_011975.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:322171-323394:- gene-YHR107C_PE2H4 rna-NM_001179237.1_PE2H4 cds-NP_011975.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:326813-328036:- gene-YHR107C_S288C rna-NM_001179237.1_S288C cds-NP_011975.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:30940-32163:+ gene-YHR107C_SA1 rna-NM_001179237.1_SA1 cds-NP_011975.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:315212-316435:- gene-YHR107C_ThermosaccDry rna-NM_001179237.1_ThermosaccDry cds-NP_011975.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:322832-324055:- gene-YHR107C_VR1 rna-NM_001179237.1_VR1 cds-NP_011975.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:306248-307471:- gene-YHR107C_ZTW1 rna-NM_001179237.1_ZTW1 cds-NP_011975.1_ZTW1 99.4 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:311890-313113:- gene-YHR107C_Sparadoxus rna-NM_001179237.1_Sparadoxus cds-NP_011975.1_Sparadoxus 91.7 100.0 Verified 1 1 1 False True False False False

Additional files