CDC10 (YCR002C)


Gene profile

Gene name: CDC10
Reference locus (S288C): YCR002C
Gene biotype: protein_coding

Description: Cell division control protein 10; Component of the septin ring, required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus interacts with phosphatidylinositol-4,5-bisphosphate; protein abundance increases under DNA damage stress

Top 10 interactors (score): CDC3 (0.999); CDC12 (0.998); CDC11 (0.996); GIN4 (0.98); SHS1 (0.973); SPR3 (0.965); KCC4 (0.96); SPR28 (0.953); BUD4 (0.947); BNI4 (0.926); YSW1 (0.907); HSL1 (0.869); CDC42 (0.837); BNI5 (0.835); HOF1 (0.832); CLA4 (0.818); BNI1 (0.797); BUD3 (0.71); SYP1 (0.695); YIL108W (0.692)

Homologues (species, bitscore): SEPT9 (Homo sapiens, 292.4); Sept9 (Mus musculus, 290.4); sept9a (Danio rerio, 294.3); sept3 (Xenopus tropicalis, 285.0); pnut (Drosophila melanogaster, 255.8); unc-59 (Caenorhabditis elegans, 222.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:112089-113057:- gene-YCR002C_AKU4011 rna-NM_001178715.1_AKU4011 cds-NP_009928.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000178.1:32973-33941:+ gene-YCR002C_BG1 rna-NM_001178715.1_BG1 cds-NP_009928.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:107903-108871:- gene-YCR002C_Bruggeman rna-NM_001178715.1_Bruggeman cds-NP_009928.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:111837-112805:- gene-YCR002C_CAT1 rna-NM_001178715.1_CAT1 cds-NP_009928.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:112738-113706:- gene-YCR002C_CBS1585 rna-NM_001178715.1_CBS1585 cds-NP_009928.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:117663-118631:- gene-YCR002C_CBS436 rna-NM_001178715.1_CBS436 cds-NP_009928.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:100198-101166:- gene-YCR002C_CBS6412 rna-NM_001178715.1_CBS6412 cds-NP_009928.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:112045-113013:- gene-YCR002C_CBS6413 rna-NM_001178715.1_CBS6413 cds-NP_009928.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:116855-117823:- gene-YCR002C_CENPK1137D rna-NM_001178715.1_CENPK1137D cds-NP_009928.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:110107-111075:- gene-YCR002C_EthanolRed rna-NM_001178715.1_EthanolRed cds-NP_009928.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:112405-113373:- gene-YCR002C_FaliES1 rna-NM_001178715.1_FaliES1 cds-NP_009928.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000126.1:26578-27546:- gene-YCR002C_JAY291 rna-NM_001178715.1_JAY291 cds-NP_009928.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:105120-106088:- gene-YCR002C_MUCL30387 rna-NM_001178715.1_MUCL30387 cds-NP_009928.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:104676-105644:- gene-YCR002C_MUCL30388 rna-NM_001178715.1_MUCL30388 cds-NP_009928.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:113155-114123:- gene-YCR002C_MUCL39482 rna-NM_001178715.1_MUCL39482 cds-NP_009928.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:108395-109363:- gene-YCR002C_MUCL42920 rna-NM_001178715.1_MUCL42920 cds-NP_009928.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:117012-117980:- gene-YCR002C_NCIM3186 rna-NM_001178715.1_NCIM3186 cds-NP_009928.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:113638-114606:- gene-YCR002C_NCYC1407 rna-NM_001178715.1_NCYC1407 cds-NP_009928.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:117810-118778:- gene-YCR002C_PE2H3 rna-NM_001178715.1_PE2H3 cds-NP_009928.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:117774-118742:- gene-YCR002C_PE2H4 rna-NM_001178715.1_PE2H4 cds-NP_009928.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:117380-118348:- gene-YCR002C_S288C rna-NM_001178715.1_S288C cds-NP_009928.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000073.1:32985-33953:+ gene-YCR002C_SA1 rna-NM_001178715.1_SA1 cds-NP_009928.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:112973-113941:- gene-YCR002C_ThermosaccDry rna-NM_001178715.1_ThermosaccDry cds-NP_009928.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:123644-124612:- gene-YCR002C_VR1 rna-NM_001178715.1_VR1 cds-NP_009928.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:111909-112877:- gene-YCR002C_ZTW1 rna-NM_001178715.1_ZTW1 cds-NP_009928.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:142763-143731:- gene-YCR002C_Sparadoxus rna-NM_001178715.1_Sparadoxus cds-NP_009928.1_Sparadoxus 93.0 100.0 Verified 1 1 1 False True False False False

Additional files