Gene name: CDC1
Reference locus (S288C): YDR182W
Gene biotype: protein_coding
Description: Cell division control protein 1; Putative mannose-ethanolamine phosphate phosphodiesterase; involved in GPI-anchor remodeling prior to the attachment of cell wall proteins to beta 1,3-glucan, removing ethanolamine phosphate from the first mannose of GPI anchors; mutants display elevated Ca2+-dependent signaling resulting in secondary actin polarization and Golgi inheritance defects; enzyme is Mn2+-dependent; mutants have cell division cycle defect and fragile cell walls; Belongs to the metallophosphoesterase superfamily. MPPE1 family
Top 10 interactors (score): PER1 (0.983); SMF1 (0.916); GPI10 (0.872); TED1 (0.849); CCH1 (0.817); BST1 (0.785); MCD4 (0.785); SMF2 (0.777); CDC27 (0.77); YMR155W (0.716); MID1 (0.71); GPI8 (0.678); POL3 (0.657); GPI18 (0.652); GPI16 (0.646); GPI13 (0.645); SMP3 (0.631); CWH43 (0.624); ATC1 (0.619); MAN2 (0.618)
Homologues (species, bitscore): MPPE1 (Homo sapiens, 75.5); Mppe1 (Mus musculus, 80.5); mppe1 (Danio rerio, 88.2); mppe1 (Xenopus tropicalis, 96.7); PGAP5 (Drosophila melanogaster, 71.6); ZK792.7 (Caenorhabditis elegans, 75.1); AT1G53710 (Arabidopsis thaliana, 126.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:796110-797585:+ | gene-YDR182W_AKU4011 | rna-NM_001180490.1_AKU4011 | cds-NP_010468.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:328214-329689:- | gene-YDR182W_BG1 | rna-NM_001180490.1_BG1 | cds-NP_010468.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:828532-830007:+ | gene-YDR182W_Bruggeman | rna-NM_001180490.1_Bruggeman | cds-NP_010468.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:815779-817254:+ | gene-YDR182W_CAT1 | rna-NM_001180490.1_CAT1 | cds-NP_010468.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:786477-787952:+ | gene-YDR182W_CBS1585 | rna-NM_001180490.1_CBS1585 | cds-NP_010468.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:815461-816936:+ | gene-YDR182W_CBS436 | rna-NM_001180490.1_CBS436 | cds-NP_010468.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:783282-784757:+ | gene-YDR182W_CBS6412 | rna-NM_001180490.1_CBS6412 | cds-NP_010468.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:813825-815300:+ | gene-YDR182W_CBS6413 | rna-NM_001180490.1_CBS6413 | cds-NP_010468.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:826415-827890:+ | gene-YDR182W_CENPK1137D | rna-NM_001180490.1_CENPK1137D | cds-NP_010468.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:796879-798354:+ | gene-YDR182W_EthanolRed | rna-NM_001180490.1_EthanolRed | cds-NP_010468.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:805091-806566:+ | gene-YDR182W_FaliES1 | rna-NM_001180490.1_FaliES1 | cds-NP_010468.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:42797-44272:- | gene-YDR182W_JAY291 | rna-NM_001180490.1_JAY291 | cds-NP_010468.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:814178-815653:+ | gene-YDR182W_MUCL30387 | rna-NM_001180490.1_MUCL30387 | cds-NP_010468.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:802420-803895:+ | gene-YDR182W_MUCL30388 | rna-NM_001180490.1_MUCL30388 | cds-NP_010468.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:787924-789399:+ | gene-YDR182W_MUCL39482 | rna-NM_001180490.1_MUCL39482 | cds-NP_010468.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:726621-728096:+ | gene-YDR182W_MUCL42920 | rna-NM_001180490.1_MUCL42920 | cds-NP_010468.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:827505-828980:+ | gene-YDR182W_NCIM3186 | rna-NM_001180490.1_NCIM3186 | cds-NP_010468.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:791057-792532:+ | gene-YDR182W_NCYC1407 | rna-NM_001180490.1_NCYC1407 | cds-NP_010468.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:807809-809284:+ | gene-YDR182W_PE2H3 | rna-NM_001180490.1_PE2H3 | cds-NP_010468.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:807114-808589:+ | gene-YDR182W_PE2H4 | rna-NM_001180490.1_PE2H4 | cds-NP_010468.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:827582-829057:+ | gene-YDR182W_S288C | rna-NM_001180490.1_S288C | cds-NP_010468.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:173293-174768:+ | gene-YDR182W_SA1 | rna-NM_001180490.1_SA1 | cds-NP_010468.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:803246-804721:+ | gene-YDR182W_ThermosaccDry | rna-NM_001180490.1_ThermosaccDry | cds-NP_010468.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:818474-819949:+ | gene-YDR182W_VR1 | rna-NM_001180490.1_VR1 | cds-NP_010468.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:65957-67432:+ | gene-YDR182W_ZTW1 | rna-NM_001180490.1_ZTW1 | cds-NP_010468.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:808445-809923:+ | gene-YDR182W_Sparadoxus | rna-NM_001180490.1_Sparadoxus | cds-NP_010468.1_Sparadoxus | 88.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |