Gene name: CCS1
Reference locus (S288C): YMR038C
Gene biotype: protein_coding
Description: Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant; Belongs to the CCS1 family
Top 10 interactors (score): SOD1 (0.999); MIA40 (0.981); COX17 (0.968); COX19 (0.966); ERV1 (0.96); TIM13 (0.929); TIM9 (0.908); TIM10 (0.903); MDM35 (0.903); COA4 (0.9); COA6 (0.9); TIM8 (0.9); CMC2 (0.9); MIX17 (0.9); MIX14 (0.9); CCC2 (0.89); ATX1 (0.888); PCA1 (0.755); LYS12 (0.699); COX11 (0.695)
Homologues (species, bitscore): CCS (Homo sapiens, 99.4); Ccs (Mus musculus, 105.5); ccs (Danio rerio, 116.7); ccs (Xenopus tropicalis, 80.9); Ccs (Drosophila melanogaster, 80.5); CCS (Arabidopsis thaliana, 94.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:397111-397860:- | gene-YMR038C_AKU4011 | rna-NM_001182535.1_AKU4011 | cds-NP_013752.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:144992-145741:+ | gene-YMR038C_BG1 | rna-NM_001182535.1_BG1 | cds-NP_013752.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:337050-337799:- | gene-YMR038C_Bruggeman | rna-NM_001182535.1_Bruggeman | cds-NP_013752.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:339566-340315:- | gene-YMR038C_CAT1 | rna-NM_001182535.1_CAT1 | cds-NP_013752.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:330052-330801:- | gene-YMR038C_CBS1585 | rna-NM_001182535.1_CBS1585 | cds-NP_013752.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:335593-336342:- | gene-YMR038C_CBS436 | rna-NM_001182535.1_CBS436 | cds-NP_013752.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:443454-444203:- | gene-YMR038C_CBS6412 | rna-NM_001182535.1_CBS6412 | cds-NP_013752.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:329308-330057:- | gene-YMR038C_CBS6413 | rna-NM_001182535.1_CBS6413 | cds-NP_013752.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:342240-342989:- | gene-YMR038C_CENPK1137D | rna-NM_001182535.1_CENPK1137D | cds-NP_013752.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:329884-330633:- | gene-YMR038C_EthanolRed | rna-NM_001182535.1_EthanolRed | cds-NP_013752.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:333066-333815:- | gene-YMR038C_FaliES1 | rna-NM_001182535.1_FaliES1 | cds-NP_013752.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:103128-103877:+ | gene-YMR038C_JAY291 | rna-NM_001182535.1_JAY291 | cds-NP_013752.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:335009-335758:- | gene-YMR038C_MUCL30387 | rna-NM_001182535.1_MUCL30387 | cds-NP_013752.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:339429-340178:- | gene-YMR038C_MUCL30388 | rna-NM_001182535.1_MUCL30388 | cds-NP_013752.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:330335-331084:- | gene-YMR038C_MUCL39482 | rna-NM_001182535.1_MUCL39482 | cds-NP_013752.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:336154-336903:- | gene-YMR038C_MUCL42920 | rna-NM_001182535.1_MUCL42920 | cds-NP_013752.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:347465-348214:- | gene-YMR038C_NCIM3186 | rna-NM_001182535.1_NCIM3186 | cds-NP_013752.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:330252-331001:- | gene-YMR038C_NCYC1407 | rna-NM_001182535.1_NCYC1407 | cds-NP_013752.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:336195-336944:- | gene-YMR038C_PE2H3 | rna-NM_001182535.1_PE2H3 | cds-NP_013752.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:342290-343039:- | gene-YMR038C_PE2H4 | rna-NM_001182535.1_PE2H4 | cds-NP_013752.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:347511-348260:- | gene-YMR038C_S288C | rna-NM_001182535.1_S288C | cds-NP_013752.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:190000-190749:+ | gene-YMR038C_SA1 | rna-NM_001182535.1_SA1 | cds-NP_013752.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:330135-330884:- | gene-YMR038C_ThermosaccDry | rna-NM_001182535.1_ThermosaccDry | cds-NP_013752.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:334836-335585:- | gene-YMR038C_VR1 | rna-NM_001182535.1_VR1 | cds-NP_013752.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:309151-309900:- | gene-YMR038C_ZTW1 | rna-NM_001182535.1_ZTW1 | cds-NP_013752.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:343054-343803:- | gene-YMR038C_Sparadoxus | rna-NM_001182535.1_Sparadoxus | cds-NP_013752.1_Sparadoxus | 89.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |