CCR4 (YAL021C)


Gene profile

Gene name: CCR4
Reference locus (S288C): YAL021C
Gene biotype: protein_coding

Description: Glucose-repressible alcohol dehydrogenase transcriptional effector; Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening; Belongs to the CCR4/nocturin family

Top 10 interactors (score): CDC39 (0.999); MOT2 (0.999); NOT3 (0.999); NOT5 (0.999); CAF40 (0.999); CDC36 (0.999); POP2 (0.999); PAN2 (0.994); CAF130 (0.994); DHH1 (0.992); PUF3 (0.982); CAF16 (0.98); PAB1 (0.978); PAN3 (0.971); XRN1 (0.969); MPT5 (0.963); CAF4 (0.961); EDC3 (0.955); LSM1 (0.953); BTT1 (0.933)

Homologues (species, bitscore): CNOT6 (Homo sapiens, 308.5); Cnot6l (Mus musculus, 301.6); cnot6 (Danio rerio, 297.0); cnot6l (Xenopus tropicalis, 299.3); twin (Drosophila melanogaster, 332.0); ccr-4 (Caenorhabditis elegans, 253.1); AT3G58560 (Arabidopsis thaliana, 193.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:95965-98472:- gene-YAL021C_AKU4011 rna-NM_001178166.1_AKU4011 cds-NP_009381.1_AKU4011 99.0 99.7 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:82916-85420:- gene-YAL021C_BG1 rna-NM_001178166.1_BG1 cds-NP_009381.1_BG1 99.4 99.6 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:110836-113343:- gene-YAL021C_Bruggeman rna-NM_001178166.1_Bruggeman cds-NP_009381.1_Bruggeman 99.2 99.7 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:97173-99680:- gene-YAL021C_CAT1 rna-NM_001178166.1_CAT1 cds-NP_009381.1_CAT1 99.1 99.7 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:108984-111491:- gene-YAL021C_CBS1585 rna-NM_001178166.1_CBS1585 cds-NP_009381.1_CBS1585 99.0 99.7 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:109235-111760:- gene-YAL021C_CBS436 rna-NM_001178166.1_CBS436 cds-NP_009381.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:722080-724578:- gene-YAL021C_CBS6412 rna-NM_001178166.1_CBS6412 cds-NP_009381.1_CBS6412 98.6 99.4 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:107247-109754:- gene-YAL021C_CBS6413 rna-NM_001178166.1_CBS6413 cds-NP_009381.1_CBS6413 99.0 99.7 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:110970-113517:- gene-YAL021C_CENPK1137D rna-NM_001178166.1_CENPK1137D cds-NP_009381.1_CENPK1137D 96.1 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:97386-99893:- gene-YAL021C_EthanolRed rna-NM_001178166.1_EthanolRed cds-NP_009381.1_EthanolRed 98.8 99.7 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:112010-114517:- gene-YAL021C_FaliES1 rna-NM_001178166.1_FaliES1 cds-NP_009381.1_FaliES1 98.8 99.7 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:83284-85788:- gene-YAL021C_JAY291 rna-NM_001178166.1_JAY291 cds-NP_009381.1_JAY291 99.3 99.6 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:111963-114470:- gene-YAL021C_MUCL30387 rna-NM_001178166.1_MUCL30387 cds-NP_009381.1_MUCL30387 99.2 99.7 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:108485-110992:- gene-YAL021C_MUCL30388 rna-NM_001178166.1_MUCL30388 cds-NP_009381.1_MUCL30388 99.0 99.7 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:107766-110273:- gene-YAL021C_MUCL39482 rna-NM_001178166.1_MUCL39482 cds-NP_009381.1_MUCL39482 99.0 99.7 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:110145-112652:- gene-YAL021C_MUCL42920 rna-NM_001178166.1_MUCL42920 cds-NP_009381.1_MUCL42920 98.9 99.7 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:110723-113236:- gene-YAL021C_NCIM3186 rna-NM_001178166.1_NCIM3186 cds-NP_009381.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:95655-98162:- gene-YAL021C_NCYC1407 rna-NM_001178166.1_NCYC1407 cds-NP_009381.1_NCYC1407 99.0 99.7 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:97569-100076:- gene-YAL021C_PE2H3 rna-NM_001178166.1_PE2H3 cds-NP_009381.1_PE2H3 99.4 99.7 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:97288-99795:- gene-YAL021C_PE2H4 rna-NM_001178166.1_PE2H4 cds-NP_009381.1_PE2H4 99.4 99.7 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:110846-113359:- gene-YAL021C_S288C rna-NM_001178166.1_S288C cds-NP_009381.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000077.1:27712-30228:- gene-YAL021C_SA1 rna-NM_001178166.1_SA1 cds-NP_009381.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:111523-114030:- gene-YAL021C_ThermosaccDry rna-NM_001178166.1_ThermosaccDry cds-NP_009381.1_ThermosaccDry 98.8 99.7 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:112816-115320:- gene-YAL021C_VR1 rna-NM_001178166.1_VR1 cds-NP_009381.1_VR1 99.2 99.6 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:83334-85841:- gene-YAL021C_ZTW1 rna-NM_001178166.1_ZTW1 cds-NP_009381.1_ZTW1 98.8 99.7 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:100900-103404:- gene-YAL021C_Sparadoxus rna-NM_001178166.1_Sparadoxus cds-NP_009381.1_Sparadoxus 92.0 99.6 Verified 1 1 1 False True False False False

Additional files