CBP3 (YPL215W)


Gene profile

Gene name: CBP3
Reference locus (S288C): YPL215W
Gene biotype: protein_coding

Description: Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Cbp3p-Cbp6p complex is sequestered if assembly of Complex III is blocked, downregulating COB mRNA translation

Top 10 interactors (score): CBP6 (0.987); CBP4 (0.986); COB (0.978); BCS1 (0.969); QCR8 (0.963); QCR7 (0.96); QCR6 (0.957); QCR2 (0.954); QCR9 (0.953); COR1 (0.949); CYT1 (0.941); MRP20 (0.932); MSS51 (0.884); QCR10 (0.858); CYC1 (0.852); OLI1 (0.848); CBS2 (0.816); MRPL4 (0.811); PET309 (0.795); RIP1 (0.786)

Homologues (species, bitscore): UQCC1 (Homo sapiens, 76.3); Uqcc1 (Mus musculus, 75.9); uqcc1 (Danio rerio, 81.3); uqcc (Xenopus tropicalis, 75.9); CG10075 (Drosophila melanogaster, 79.3); C35D10.5 (Caenorhabditis elegans, 62.4); AT5G51220 (Arabidopsis thaliana, 50.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:125288-126295:+ gene-YPL215W_AKU4011 rna-NM_001184029.1_AKU4011 cds-NP_015109.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:331059-332066:+ gene-YPL215W_BG1 rna-NM_001184029.1_BG1 cds-NP_015109.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:150753-151760:+ gene-YPL215W_Bruggeman rna-NM_001184029.1_Bruggeman cds-NP_015109.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:147361-148368:+ gene-YPL215W_CAT1 rna-NM_001184029.1_CAT1 cds-NP_015109.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:129474-130481:+ gene-YPL215W_CBS1585 rna-NM_001184029.1_CBS1585 cds-NP_015109.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:143897-144904:+ gene-YPL215W_CBS436 rna-NM_001184029.1_CBS436 cds-NP_015109.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:134277-135284:+ gene-YPL215W_CBS6412 rna-NM_001184029.1_CBS6412 cds-NP_015109.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:125651-126658:+ gene-YPL215W_CBS6413 rna-NM_001184029.1_CBS6413 cds-NP_015109.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:147353-148360:+ gene-YPL215W_CENPK1137D rna-NM_001184029.1_CENPK1137D cds-NP_015109.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:124387-125394:+ gene-YPL215W_EthanolRed rna-NM_001184029.1_EthanolRed cds-NP_015109.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:131593-132600:+ gene-YPL215W_FaliES1 rna-NM_001184029.1_FaliES1 cds-NP_015109.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000069.1:25708-26715:- gene-YPL215W_JAY291 rna-NM_001184029.1_JAY291 cds-NP_015109.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:142462-143469:+ gene-YPL215W_MUCL30387 rna-NM_001184029.1_MUCL30387 cds-NP_015109.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:140653-141660:+ gene-YPL215W_MUCL30388 rna-NM_001184029.1_MUCL30388 cds-NP_015109.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:122604-123611:+ gene-YPL215W_MUCL39482 rna-NM_001184029.1_MUCL39482 cds-NP_015109.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:141487-142494:+ gene-YPL215W_MUCL42920 rna-NM_001184029.1_MUCL42920 cds-NP_015109.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:147399-148406:+ gene-YPL215W_NCIM3186 rna-NM_001184029.1_NCIM3186 cds-NP_015109.1_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:129052-130059:+ gene-YPL215W_NCYC1407 rna-NM_001184029.1_NCYC1407 cds-NP_015109.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:136759-137766:+ gene-YPL215W_PE2H3 rna-NM_001184029.1_PE2H3 cds-NP_015109.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:136402-137409:+ gene-YPL215W_PE2H4 rna-NM_001184029.1_PE2H4 cds-NP_015109.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:147416-148423:+ gene-YPL215W_S288C rna-NM_001184029.1_S288C cds-NP_015109.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000095.1:25758-26765:- gene-YPL215W_SA1 rna-NM_001184029.1_SA1 cds-NP_015109.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:131374-132381:+ gene-YPL215W_ThermosaccDry rna-NM_001184029.1_ThermosaccDry cds-NP_015109.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:145440-146447:+ gene-YPL215W_VR1 rna-NM_001184029.1_VR1 cds-NP_015109.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:130903-131911:+ gene-YPL215W_ZTW1 rna-NM_001184029.1_ZTW1 cds-NP_015109.1_ZTW1 99.7 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:132484-133491:+ gene-YPL215W_Sparadoxus rna-NM_001184029.1_Sparadoxus cds-NP_015109.1_Sparadoxus 90.7 100.0 Verified 1 1 1 False True False False False

Additional files