Gene name: CBK1
Reference locus (S288C): YNL161W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase CBK1; Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress
Top 10 interactors (score): MOB2 (0.999); TAO3 (0.999); MOB1 (0.998); HYM1 (0.997); SOG2 (0.995); SSD1 (0.992); ACE2 (0.992); CDC14 (0.991); SWI5 (0.969); LRE1 (0.918); KIC1 (0.888); ATG2 (0.816); CTS1 (0.812); CDC42 (0.777); SRL1 (0.775); ATG4 (0.763); BCK2 (0.741); ZRG8 (0.733); SEC2 (0.73); COT1 (0.719)
Homologues (species, bitscore): STK38L (Homo sapiens, 468.4); Stk38l (Mus musculus, 469.5); stk38l (Danio rerio, 469.9); stk38l (Xenopus tropicalis, 464.5); trc (Drosophila melanogaster, 467.2); sax-1 (Caenorhabditis elegans, 469.9); AT4G14350 (Arabidopsis thaliana, 436.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:326317-328581:+ | gene-YNL161W_AKU4011 | rna-NM_001182999.3_AKU4011 | cds-NP_014238.3_AKU4011 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:230289-232607:+ | gene-YNL161W_BG1 | rna-NM_001182999.3_BG1 | cds-NP_014238.3_BG1 | 97.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:336382-338646:+ | gene-YNL161W_Bruggeman | rna-NM_001182999.3_Bruggeman | cds-NP_014238.3_Bruggeman | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:379258-381573:+ | gene-YNL161W_CAT1 | rna-NM_001182999.3_CAT1 | cds-NP_014238.3_CAT1 | 97.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:326969-329233:+ | gene-YNL161W_CBS1585 | rna-NM_001182999.3_CBS1585 | cds-NP_014238.3_CBS1585 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:395296-397584:+ | gene-YNL161W_CBS436 | rna-NM_001182999.3_CBS436 | cds-NP_014238.3_CBS436 | 98.5 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:322374-324638:+ | gene-YNL161W_CBS6412 | rna-NM_001182999.3_CBS6412 | cds-NP_014238.3_CBS6412 | 99.6 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:323402-325666:+ | gene-YNL161W_CBS6413 | rna-NM_001182999.3_CBS6413 | cds-NP_014238.3_CBS6413 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:326411-328681:+ | gene-YNL161W_CENPK1137D | rna-NM_001182999.3_CENPK1137D | cds-NP_014238.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:323300-325564:+ | gene-YNL161W_EthanolRed | rna-NM_001182999.3_EthanolRed | cds-NP_014238.3_EthanolRed | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:319213-321477:+ | gene-YNL161W_FaliES1 | rna-NM_001182999.3_FaliES1 | cds-NP_014238.3_FaliES1 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000439.1:22174-24465:- | gene-YNL161W_JAY291 | rna-NM_001182999.3_JAY291 | cds-NP_014238.3_JAY291 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:332201-334468:+ | gene-YNL161W_MUCL30387 | rna-NM_001182999.3_MUCL30387 | cds-NP_014238.3_MUCL30387 | 99.4 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:366756-369020:+ | gene-YNL161W_MUCL30388 | rna-NM_001182999.3_MUCL30388 | cds-NP_014238.3_MUCL30388 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:324208-326472:+ | gene-YNL161W_MUCL39482 | rna-NM_001182999.3_MUCL39482 | cds-NP_014238.3_MUCL39482 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:326611-328875:+ | gene-YNL161W_MUCL42920 | rna-NM_001182999.3_MUCL42920 | cds-NP_014238.3_MUCL42920 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:332566-334836:+ | gene-YNL161W_NCIM3186 | rna-NM_001182999.3_NCIM3186 | cds-NP_014238.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:326302-328566:+ | gene-YNL161W_NCYC1407 | rna-NM_001182999.3_NCYC1407 | cds-NP_014238.3_NCYC1407 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:323267-325558:+ | gene-YNL161W_PE2H3 | rna-NM_001182999.3_PE2H3 | cds-NP_014238.3_PE2H3 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:322655-324946:+ | gene-YNL161W_PE2H4 | rna-NM_001182999.3_PE2H4 | cds-NP_014238.3_PE2H4 | 98.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:332597-334867:+ | gene-YNL161W_S288C | rna-NM_001182999.3_S288C | cds-NP_014238.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:78684-80978:- | gene-YNL161W_SA1 | rna-NM_001182999.3_SA1 | cds-NP_014238.3_SA1 | 98.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:320070-322334:+ | gene-YNL161W_ThermosaccDry | rna-NM_001182999.3_ThermosaccDry | cds-NP_014238.3_ThermosaccDry | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:338590-340887:+ | gene-YNL161W_VR1 | rna-NM_001182999.3_VR1 | cds-NP_014238.3_VR1 | 98.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:229892-232156:+ | gene-YNL161W_ZTW1 | rna-NM_001182999.3_ZTW1 | cds-NP_014238.3_ZTW1 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:330678-332945:+ | gene-YNL161W_Sparadoxus | rna-NM_001182999.3_Sparadoxus | cds-NP_014238.3_Sparadoxus | 90.1 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |