Gene name: CBF2
Reference locus (S288C): YGR140W
Gene biotype: protein_coding
Description: Essential kinetochore protein; component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo; sumoylated in an Mms21p-dependent manner; relative distribution to the spindle pole body decreases upon DNA replication stress
Top 10 interactors (score): SKP1 (0.999); CTF13 (0.999); CEP3 (0.999); BIR1 (0.997); CBF1 (0.991); SCM3 (0.991); CSE4 (0.973); SLI15 (0.972); IPL1 (0.964); CTF19 (0.943); CHL4 (0.941); DSN1 (0.941); OGG1 (0.9); MTW1 (0.867); NUF2 (0.861); DAM1 (0.852); MCM21 (0.835); SPC24 (0.835); SPC105 (0.832); OKP1 (0.832)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:746907-749778:+ | gene-YGR140W_AKU4011 | rna-NM_001181269.3_AKU4011 | cds-NP_011656.3_AKU4011 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:25179-28049:+ | gene-YGR140W_BG1 | rna-NM_001181269.3_BG1 | cds-NP_011656.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:749205-752436:+ | gene-YGR140W_Bruggeman | rna-NM_001181269.3_Bruggeman | cds-NP_011656.3_Bruggeman | 88.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:748448-751318:+ | gene-YGR140W_CAT1 | rna-NM_001181269.3_CAT1 | cds-NP_011656.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:747641-750512:+ | gene-YGR140W_CBS1585 | rna-NM_001181269.3_CBS1585 | cds-NP_011656.3_CBS1585 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:751029-753899:+ | gene-YGR140W_CBS436 | rna-NM_001181269.3_CBS436 | cds-NP_011656.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:738662-741533:+ | gene-YGR140W_CBS6412 | rna-NM_001181269.3_CBS6412 | cds-NP_011656.3_CBS6412 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:744499-747370:+ | gene-YGR140W_CBS6413 | rna-NM_001181269.3_CBS6413 | cds-NP_011656.3_CBS6413 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:767162-770032:+ | gene-YGR140W_CENPK1137D | rna-NM_001181269.3_CENPK1137D | cds-NP_011656.3_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:733206-736077:+ | gene-YGR140W_EthanolRed | rna-NM_001181269.3_EthanolRed | cds-NP_011656.3_EthanolRed | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:737294-740165:+ | gene-YGR140W_FaliES1 | rna-NM_001181269.3_FaliES1 | cds-NP_011656.3_FaliES1 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000438.1:3449-6319:+ | gene-YGR140W_JAY291 | rna-NM_001181269.3_JAY291 | cds-NP_011656.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:748438-751309:+ | gene-YGR140W_MUCL30387 | rna-NM_001181269.3_MUCL30387 | cds-NP_011656.3_MUCL30387 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:749467-752338:+ | gene-YGR140W_MUCL30388 | rna-NM_001181269.3_MUCL30388 | cds-NP_011656.3_MUCL30388 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:743117-745988:+ | gene-YGR140W_MUCL39482 | rna-NM_001181269.3_MUCL39482 | cds-NP_011656.3_MUCL39482 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:753465-756335:+ | gene-YGR140W_MUCL42920 | rna-NM_001181269.3_MUCL42920 | cds-NP_011656.3_MUCL42920 | 98.9 | 99.9 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:767429-770299:+ | gene-YGR140W_NCIM3186 | rna-NM_001181269.3_NCIM3186 | cds-NP_011656.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:738317-741188:+ | gene-YGR140W_NCYC1407 | rna-NM_001181269.3_NCYC1407 | cds-NP_011656.3_NCYC1407 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:757671-760541:+ | gene-YGR140W_PE2H3 | rna-NM_001181269.3_PE2H3 | cds-NP_011656.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:762781-765651:+ | gene-YGR140W_PE2H4 | rna-NM_001181269.3_PE2H4 | cds-NP_011656.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:767429-770299:+ | gene-YGR140W_S288C | rna-NM_001181269.3_S288C | cds-NP_011656.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:2548-5419:+ | gene-YGR140W_SA1 | rna-NM_001181269.3_SA1 | cds-NP_011656.3_SA1 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:757917-760788:+ | gene-YGR140W_ThermosaccDry | rna-NM_001181269.3_ThermosaccDry | cds-NP_011656.3_ThermosaccDry | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:861914-864784:+ | gene-YGR140W_VR1 | rna-NM_001181269.3_VR1 | cds-NP_011656.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:60061-62931:+ | gene-YGR140W_ZTW1 | rna-NM_001181269.3_ZTW1 | cds-NP_011656.3_ZTW1 | 99.1 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:747768-750642:+ | gene-YGR140W_Sparadoxus | rna-NM_001181269.3_Sparadoxus | cds-NP_011656.3_Sparadoxus | 87.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |