Gene name: CBF1
Reference locus (S288C): YJR060W
Gene biotype: protein_coding
Description: Centromere-binding protein 1; Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): MET4 (0.999); MET28 (0.999); CBF2 (0.991); MET32 (0.988); CSE4 (0.986); CEP3 (0.97); CTF13 (0.952); MET31 (0.944); SKP1 (0.935); PHO4 (0.909); AFT1 (0.895); TYE7 (0.887); MET30 (0.867); INO4 (0.853); MET16 (0.853); NAM2 (0.814); RAP1 (0.812); INO2 (0.795); REB1 (0.789); GCN4 (0.783)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:520290-521345:+ | gene-YJR060W_AKU4011 | rna-NM_001181718.1_AKU4011 | cds-NP_012594.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:86280-87335:- | gene-YJR060W_BG1 | rna-NM_001181718.1_BG1 | cds-NP_012594.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:533796-534851:+ | gene-YJR060W_Bruggeman | rna-NM_001181718.1_Bruggeman | cds-NP_012594.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:538107-539162:+ | gene-YJR060W_CAT1 | rna-NM_001181718.1_CAT1 | cds-NP_012594.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:532354-533409:+ | gene-YJR060W_CBS1585 | rna-NM_001181718.1_CBS1585 | cds-NP_012594.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:550421-551476:+ | gene-YJR060W_CBS436 | rna-NM_001181718.1_CBS436 | cds-NP_012594.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:519503-520558:+ | gene-YJR060W_CBS6412 | rna-NM_001181718.1_CBS6412 | cds-NP_012594.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:521799-522854:+ | gene-YJR060W_CBS6413 | rna-NM_001181718.1_CBS6413 | cds-NP_012594.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:531116-532171:+ | gene-YJR060W_CENPK1137D | rna-NM_001181718.1_CENPK1137D | cds-NP_012594.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:524683-525738:+ | gene-YJR060W_EthanolRed | rna-NM_001181718.1_EthanolRed | cds-NP_012594.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:536149-537204:+ | gene-YJR060W_FaliES1 | rna-NM_001181718.1_FaliES1 | cds-NP_012594.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:152187-153242:- | gene-YJR060W_JAY291 | rna-NM_001181718.1_JAY291 | cds-NP_012594.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:534332-535387:+ | gene-YJR060W_MUCL30387 | rna-NM_001181718.1_MUCL30387 | cds-NP_012594.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:531620-532675:+ | gene-YJR060W_MUCL30388 | rna-NM_001181718.1_MUCL30388 | cds-NP_012594.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:525816-526871:+ | gene-YJR060W_MUCL39482 | rna-NM_001181718.1_MUCL39482 | cds-NP_012594.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:530053-531108:+ | gene-YJR060W_MUCL42920 | rna-NM_001181718.1_MUCL42920 | cds-NP_012594.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:548738-549793:+ | gene-YJR060W_NCIM3186 | rna-NM_001181718.1_NCIM3186 | cds-NP_012594.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:523380-524435:+ | gene-YJR060W_NCYC1407 | rna-NM_001181718.1_NCYC1407 | cds-NP_012594.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:541270-542325:+ | gene-YJR060W_PE2H3 | rna-NM_001181718.1_PE2H3 | cds-NP_012594.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:534966-536021:+ | gene-YJR060W_PE2H4 | rna-NM_001181718.1_PE2H4 | cds-NP_012594.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:548759-549814:+ | gene-YJR060W_S288C | rna-NM_001181718.1_S288C | cds-NP_012594.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:7336-8391:+ | gene-YJR060W_SA1 | rna-NM_001181718.1_SA1 | cds-NP_012594.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:530079-531134:+ | gene-YJR060W_ThermosaccDry | rna-NM_001181718.1_ThermosaccDry | cds-NP_012594.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:531956-533011:+ | gene-YJR060W_VR1 | rna-NM_001181718.1_VR1 | cds-NP_012594.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:509479-510534:+ | gene-YJR060W_ZTW1 | rna-NM_001181718.1_ZTW1 | cds-NP_012594.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:542875-543924:+ | gene-YJR060W_Sparadoxus | rna-NM_001181718.1_Sparadoxus | cds-NP_012594.1_Sparadoxus | 88.7 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |