CAR2 (YLR438W)


Gene profile

Gene name: CAR2
Reference locus (S288C): YLR438W
Gene biotype: protein_coding

Description: L-ornithine transaminase (OTAse); catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive; protein abundance increases in response to DNA replication stress; human homolog OAT complements yeast null mutant

Top 10 interactors (score): CAR1 (0.999); ARG3 (0.998); PRO2 (0.998); PRO1 (0.996); PUT2 (0.991); SPE1 (0.989); PRO3 (0.981); YHR033W (0.967); ARG5,6 (0.963); PUT1 (0.937); ARG1 (0.888); ARG4 (0.88); DUR1,2 (0.843); CPA2 (0.798); UME6 (0.78); ARG7 (0.768); UGA2 (0.741); SPE3 (0.734); GDH2 (0.721); ARG80 (0.693)

Homologues (species, bitscore): OAT (Homo sapiens, 413.7); Oat (Mus musculus, 418.3); oat (Danio rerio, 426.4); oat.1 (Xenopus tropicalis, 429.5); Oat (Drosophila melanogaster, 425.2); C16A3.10 (Caenorhabditis elegans, 419.1); DELTA-OAT (Arabidopsis thaliana, 448.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:950763-952037:+ gene-YLR438W_AKU4011 rna-NM_001182326.1_AKU4011 cds-NP_013542.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:183222-184496:+ gene-YLR438W_BG1 rna-NM_001182326.1_BG1 cds-NP_013542.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:989067-990341:+ gene-YLR438W_Bruggeman rna-NM_001182326.1_Bruggeman cds-NP_013542.1_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:985078-986352:+ gene-YLR438W_CAT1 rna-NM_001182326.1_CAT1 cds-NP_013542.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:986354-987628:+ gene-YLR438W_CBS1585 rna-NM_001182326.1_CBS1585 cds-NP_013542.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:975700-976974:+ gene-YLR438W_CBS436 rna-NM_001182326.1_CBS436 cds-NP_013542.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:1022394-1023668:+ gene-YLR438W_CBS6412 rna-NM_001182326.1_CBS6412 cds-NP_013542.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:987142-988416:+ gene-YLR438W_CBS6413 rna-NM_001182326.1_CBS6413 cds-NP_013542.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:997118-998392:+ gene-YLR438W_CENPK1137D rna-NM_001182326.1_CENPK1137D cds-NP_013542.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:943785-945059:+ gene-YLR438W_EthanolRed rna-NM_001182326.1_EthanolRed cds-NP_013542.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:979056-980330:+ gene-YLR438W_FaliES1 rna-NM_001182326.1_FaliES1 cds-NP_013542.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000194.1:38359-39633:- gene-YLR438W_JAY291 rna-NM_001182326.1_JAY291 cds-NP_013542.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:987928-989202:+ gene-YLR438W_MUCL30387 rna-NM_001182326.1_MUCL30387 cds-NP_013542.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:995285-996559:+ gene-YLR438W_MUCL30388 rna-NM_001182326.1_MUCL30388 cds-NP_013542.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:987574-988848:+ gene-YLR438W_MUCL39482 rna-NM_001182326.1_MUCL39482 cds-NP_013542.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:988076-989350:+ gene-YLR438W_MUCL42920 rna-NM_001182326.1_MUCL42920 cds-NP_013542.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:1012475-1013749:+ gene-YLR438W_NCIM3186 rna-NM_001182326.1_NCIM3186 cds-NP_013542.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:997008-998282:+ gene-YLR438W_NCYC1407 rna-NM_001182326.1_NCYC1407 cds-NP_013542.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:983453-984727:+ gene-YLR438W_PE2H3 rna-NM_001182326.1_PE2H3 cds-NP_013542.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:983197-984471:+ gene-YLR438W_PE2H4 rna-NM_001182326.1_PE2H4 cds-NP_013542.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:1012501-1013775:+ gene-YLR438W_S288C rna-NM_001182326.1_S288C cds-NP_013542.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:46178-47452:- gene-YLR438W_SA1 rna-NM_001182326.1_SA1 cds-NP_013542.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:982135-983409:+ gene-YLR438W_ThermosaccDry rna-NM_001182326.1_ThermosaccDry cds-NP_013542.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:988558-989832:+ gene-YLR438W_VR1 rna-NM_001182326.1_VR1 cds-NP_013542.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:312407-313681:+ gene-YLR438W_ZTW1 rna-NM_001182326.1_ZTW1 cds-NP_013542.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:961530-962804:+ gene-YLR438W_Sparadoxus rna-NM_001182326.1_Sparadoxus cds-NP_013542.1_Sparadoxus 92.9 100.0 Verified 1 1 1 False True False False False

Additional files