CAP1 (YKL007W)


Gene profile

Gene name: CAP1
Reference locus (S288C): YKL007W
Gene biotype: protein_coding

Description: Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress

Top 10 interactors (score): CAP2 (0.999); SHE4 (0.989); ARC35 (0.974); ARP1 (0.926); ARP2 (0.919); BYE1 (0.912); ACT1 (0.864); ARC18 (0.852); AIP1 (0.85); COF1 (0.826); AIM21 (0.805); ARP9 (0.803); SAC6 (0.787); MTD1 (0.786); TDA2 (0.775); RPL14A (0.771); LAC1 (0.748); DYN1 (0.716); DST1 (0.708); PFY1 (0.697)

Homologues (species, bitscore): CAPZA2 (Homo sapiens, 131.7); Capza2 (Mus musculus, 134.8); capza1b (Danio rerio, 132.1); capza1 (Xenopus tropicalis, 133.7); cpa (Drosophila melanogaster, 125.6); cap-1 (Caenorhabditis elegans, 129.0); CPA (Arabidopsis thaliana, 96.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:415318-416124:+ gene-YKL007W_AKU4011 rna-NM_001179573.1_AKU4011 cds-NP_012918.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:227779-228585:- gene-YKL007W_BG1 rna-NM_001179573.1_BG1 cds-NP_012918.1_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:437024-437830:+ gene-YKL007W_Bruggeman rna-NM_001179573.1_Bruggeman cds-NP_012918.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:432130-432936:+ gene-YKL007W_CAT1 rna-NM_001179573.1_CAT1 cds-NP_012918.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:428037-428843:+ gene-YKL007W_CBS1585 rna-NM_001179573.1_CBS1585 cds-NP_012918.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:426900-427706:+ gene-YKL007W_CBS436 rna-NM_001179573.1_CBS436 cds-NP_012918.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:412194-413000:+ gene-YKL007W_CBS6412 rna-NM_001179573.1_CBS6412 cds-NP_012918.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:427892-428698:+ gene-YKL007W_CBS6413 rna-NM_001179573.1_CBS6413 cds-NP_012918.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:428979-429785:+ gene-YKL007W_CENPK1137D rna-NM_001179573.1_CENPK1137D cds-NP_012918.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:425798-426604:+ gene-YKL007W_EthanolRed rna-NM_001179573.1_EthanolRed cds-NP_012918.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:427888-428694:+ gene-YKL007W_FaliES1 rna-NM_001179573.1_FaliES1 cds-NP_012918.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000142.1:2341-3147:- gene-YKL007W_JAY291 rna-NM_001179573.1_JAY291 cds-NP_012918.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:436341-437147:+ gene-YKL007W_MUCL30387 rna-NM_001179573.1_MUCL30387 cds-NP_012918.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:431948-432754:+ gene-YKL007W_MUCL30388 rna-NM_001179573.1_MUCL30388 cds-NP_012918.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:427354-428160:+ gene-YKL007W_MUCL39482 rna-NM_001179573.1_MUCL39482 cds-NP_012918.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:433185-433991:+ gene-YKL007W_MUCL42920 rna-NM_001179573.1_MUCL42920 cds-NP_012918.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:429291-430097:+ gene-YKL007W_NCIM3186 rna-NM_001179573.1_NCIM3186 cds-NP_012918.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:427547-428353:+ gene-YKL007W_NCYC1407 rna-NM_001179573.1_NCYC1407 cds-NP_012918.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:452238-453044:+ gene-YKL007W_PE2H3 rna-NM_001179573.1_PE2H3 cds-NP_012918.1_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:436979-437785:+ gene-YKL007W_PE2H4 rna-NM_001179573.1_PE2H4 cds-NP_012918.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:429302-430108:+ gene-YKL007W_S288C rna-NM_001179573.1_S288C cds-NP_012918.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:107582-108388:+ gene-YKL007W_SA1 rna-NM_001179573.1_SA1 cds-NP_012918.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:427987-428793:+ gene-YKL007W_ThermosaccDry rna-NM_001179573.1_ThermosaccDry cds-NP_012918.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:427260-428066:+ gene-YKL007W_VR1 rna-NM_001179573.1_VR1 cds-NP_012918.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:426033-426839:+ gene-YKL007W_ZTW1 rna-NM_001179573.1_ZTW1 cds-NP_012918.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:451009-451815:+ gene-YKL007W_Sparadoxus rna-NM_001179573.1_Sparadoxus cds-NP_012918.1_Sparadoxus 89.9 100.0 Verified 1 1 1 False True False False False

Additional files