Gene name: CAF4
Reference locus (S288C): YKR036C
Gene biotype: protein_coding
Description: CCR4-associated factor 4; WD40 repeat-containing protein associated with the CCR4-NOT complex; interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission; CAF4 has a paralog, MDV1, that arose from the whole genome duplication
Top 10 interactors (score): FIS1 (0.999); MDV1 (0.999); DNM1 (0.996); CAF16 (0.978); CCR4 (0.961); POP2 (0.918); MGM1 (0.913); FZO1 (0.904); BTT1 (0.9); NOT3 (0.888); CAF40 (0.873); VPS1 (0.854); CAF130 (0.853); CDC39 (0.844); NOT5 (0.841); CDC36 (0.824); UGO1 (0.789); CDC73 (0.789); MOT2 (0.78); DBF2 (0.763)
Homologues (species, bitscore): FBXW7 (Homo sapiens, 107.8); Fbxw7 (Mus musculus, 107.8); FBXW7 (Danio rerio, 107.8); fbxw7 (Xenopus tropicalis, 107.5); ago (Drosophila melanogaster, 110.5); lin-23 (Caenorhabditis elegans, 98.2); WDR5a (Arabidopsis thaliana, 89.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:494370-496307:- | gene-YKR036C_AKU4011 | rna-NM_001179826.2_AKU4011 | cds-NP_012962.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:147170-149107:+ | gene-YKR036C_BG1 | rna-NM_001179826.2_BG1 | cds-NP_012962.3_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:516549-518486:- | gene-YKR036C_Bruggeman | rna-NM_001179826.2_Bruggeman | cds-NP_012962.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:511797-513734:- | gene-YKR036C_CAT1 | rna-NM_001179826.2_CAT1 | cds-NP_012962.3_CAT1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:507110-509047:- | gene-YKR036C_CBS1585 | rna-NM_001179826.2_CBS1585 | cds-NP_012962.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:505951-507888:- | gene-YKR036C_CBS436 | rna-NM_001179826.2_CBS436 | cds-NP_012962.3_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:491271-493208:- | gene-YKR036C_CBS6412 | rna-NM_001179826.2_CBS6412 | cds-NP_012962.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:506939-508876:- | gene-YKR036C_CBS6413 | rna-NM_001179826.2_CBS6413 | cds-NP_012962.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:508480-510411:- | gene-YKR036C_CENPK1137D | rna-NM_001179826.2_CENPK1137D | cds-NP_012962.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:504636-506573:- | gene-YKR036C_EthanolRed | rna-NM_001179826.2_EthanolRed | cds-NP_012962.3_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:507769-509706:- | gene-YKR036C_FaliES1 | rna-NM_001179826.2_FaliES1 | cds-NP_012962.3_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:44039-45976:+ | gene-YKR036C_JAY291 | rna-NM_001179826.2_JAY291 | cds-NP_012962.3_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:516699-518636:- | gene-YKR036C_MUCL30387 | rna-NM_001179826.2_MUCL30387 | cds-NP_012962.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:511313-513244:- | gene-YKR036C_MUCL30388 | rna-NM_001179826.2_MUCL30388 | cds-NP_012962.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:506428-508365:- | gene-YKR036C_MUCL39482 | rna-NM_001179826.2_MUCL39482 | cds-NP_012962.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:512467-514398:- | gene-YKR036C_MUCL42920 | rna-NM_001179826.2_MUCL42920 | cds-NP_012962.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:508691-510622:- | gene-YKR036C_NCIM3186 | rna-NM_001179826.2_NCIM3186 | cds-NP_012962.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:506634-508571:- | gene-YKR036C_NCYC1407 | rna-NM_001179826.2_NCYC1407 | cds-NP_012962.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:531635-533572:- | gene-YKR036C_PE2H3 | rna-NM_001179826.2_PE2H3 | cds-NP_012962.3_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:516358-518295:- | gene-YKR036C_PE2H4 | rna-NM_001179826.2_PE2H4 | cds-NP_012962.3_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:508702-510633:- | gene-YKR036C_S288C | rna-NM_001179826.2_S288C | cds-NP_012962.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000078.1:3104-5041:+ | gene-YKR036C_SA1 | rna-NM_001179826.2_SA1 | cds-NP_012962.3_SA1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:507022-508959:- | gene-YKR036C_ThermosaccDry | rna-NM_001179826.2_ThermosaccDry | cds-NP_012962.3_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:506655-508592:- | gene-YKR036C_VR1 | rna-NM_001179826.2_VR1 | cds-NP_012962.3_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:505069-507006:- | gene-YKR036C_ZTW1 | rna-NM_001179826.2_ZTW1 | cds-NP_012962.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:530353-532290:- | gene-YKR036C_Sparadoxus | rna-NM_001179826.2_Sparadoxus | cds-NP_012962.3_Sparadoxus | 86.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |