Gene name: CAC2
Reference locus (S288C): YML102W
Gene biotype: protein_coding
Description: Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p; chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure, deactivation of the DNA damage checkpoint after DNA repair, chromatin dynamics during transcription; and repression of divergent transcription; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): RLF2 (0.999); POL30 (0.999); MSI1 (0.999); ASF1 (0.999); RTT106 (0.996); HHT2 (0.989); HAT2 (0.988); HHT1 (0.987); HIR2 (0.979); HAT1 (0.974); POL1 (0.949); HIR3 (0.944); RTT109 (0.933); POL2 (0.932); HHF1 (0.932); MCM2 (0.927); VPS75 (0.925); PRI1 (0.92); MCM3 (0.916); SMC3 (0.915)
Homologues (species, bitscore): CHAF1B (Homo sapiens, 270.4); Chaf1b (Mus musculus, 265.8); chaf1b (Danio rerio, 273.1); chaf1b (Xenopus tropicalis, 259.6); Caf1-105 (Drosophila melanogaster, 233.4); chaf-2 (Caenorhabditis elegans, 149.1); FAS2 (Arabidopsis thaliana, 254.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:62014-63420:+ | gene-YML102W_AKU4011 | rna-NM_001182464.1_AKU4011 | cds-NP_013605.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:412707-414113:- | gene-YML102W_BG1 | rna-NM_001182464.1_BG1 | cds-NP_013605.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:68269-69675:+ | gene-YML102W_Bruggeman | rna-NM_001182464.1_Bruggeman | cds-NP_013605.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:69828-71234:+ | gene-YML102W_CAT1 | rna-NM_001182464.1_CAT1 | cds-NP_013605.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:62016-63422:+ | gene-YML102W_CBS1585 | rna-NM_001182464.1_CBS1585 | cds-NP_013605.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:68008-69414:+ | gene-YML102W_CBS436 | rna-NM_001182464.1_CBS436 | cds-NP_013605.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:62779-64185:+ | gene-YML102W_CBS6412 | rna-NM_001182464.1_CBS6412 | cds-NP_013605.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:61243-62649:+ | gene-YML102W_CBS6413 | rna-NM_001182464.1_CBS6413 | cds-NP_013605.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:62886-64292:+ | gene-YML102W_CENPK1137D | rna-NM_001182464.1_CENPK1137D | cds-NP_013605.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:62520-63926:+ | gene-YML102W_EthanolRed | rna-NM_001182464.1_EthanolRed | cds-NP_013605.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:62797-64203:+ | gene-YML102W_FaliES1 | rna-NM_001182464.1_FaliES1 | cds-NP_013605.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:25978-27384:- | gene-YML102W_JAY291 | rna-NM_001182464.1_JAY291 | cds-NP_013605.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:66714-68120:+ | gene-YML102W_MUCL30387 | rna-NM_001182464.1_MUCL30387 | cds-NP_013605.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:69939-71345:+ | gene-YML102W_MUCL30388 | rna-NM_001182464.1_MUCL30388 | cds-NP_013605.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:62030-63436:+ | gene-YML102W_MUCL39482 | rna-NM_001182464.1_MUCL39482 | cds-NP_013605.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:66829-68235:+ | gene-YML102W_MUCL42920 | rna-NM_001182464.1_MUCL42920 | cds-NP_013605.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:68248-69654:+ | gene-YML102W_NCIM3186 | rna-NM_001182464.1_NCIM3186 | cds-NP_013605.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:62824-64230:+ | gene-YML102W_NCYC1407 | rna-NM_001182464.1_NCYC1407 | cds-NP_013605.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:68258-69664:+ | gene-YML102W_PE2H3 | rna-NM_001182464.1_PE2H3 | cds-NP_013605.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:68196-69602:+ | gene-YML102W_PE2H4 | rna-NM_001182464.1_PE2H4 | cds-NP_013605.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:68294-69700:+ | gene-YML102W_S288C | rna-NM_001182464.1_S288C | cds-NP_013605.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:60262-61668:+ | gene-YML102W_SA1 | rna-NM_001182464.1_SA1 | cds-NP_013605.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:62093-63499:+ | gene-YML102W_ThermosaccDry | rna-NM_001182464.1_ThermosaccDry | cds-NP_013605.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:66477-67883:+ | gene-YML102W_VR1 | rna-NM_001182464.1_VR1 | cds-NP_013605.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:41594-43000:+ | gene-YML102W_ZTW1 | rna-NM_001182464.1_ZTW1 | cds-NP_013605.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:72958-74364:+ | gene-YML102W_Sparadoxus | rna-NM_001182464.1_Sparadoxus | cds-NP_013605.1_Sparadoxus | 88.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |