Gene name: CAB5
Reference locus (S288C): YDR196C
Gene biotype: protein_coding
Description: Dephospho-CoA kinase CAB5; Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by human homolog DCAKD and by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies; also localized to lipid droplets
Top 10 interactors (score): CAB4 (0.999); CAB2 (0.999); CAB3 (0.998); VHS3 (0.988); SIS2 (0.986); CAB1 (0.957); LYS5 (0.951); PPT2 (0.944); RMA1 (0.794); RER2 (0.728); SLM2 (0.713); DUR1,2 (0.698); KTR4 (0.696); HEM12 (0.694); PCD1 (0.689); ANR2 (0.68); CDC6 (0.679); IMD4 (0.674); YIM1 (0.648); FMN1 (0.645)
Homologues (species, bitscore): DCAKD (Homo sapiens, 143.7); Dcakd (Mus musculus, 141.7); dcakd (Danio rerio, 154.8); dcakd (Xenopus tropicalis, 146.4); Dpck (Drosophila melanogaster, 149.1); T05G5.5 (Caenorhabditis elegans, 169.9); ATCOAE (Arabidopsis thaliana, 151.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:818809-819534:- | gene-YDR196C_AKU4011 | rna-NM_001180504.3_AKU4011 | cds-NP_010482.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:306286-307011:+ | gene-YDR196C_BG1 | rna-NM_001180504.3_BG1 | cds-NP_010482.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:851221-851946:- | gene-YDR196C_Bruggeman | rna-NM_001180504.3_Bruggeman | cds-NP_010482.3_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:838488-839213:- | gene-YDR196C_CAT1 | rna-NM_001180504.3_CAT1 | cds-NP_010482.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:809169-809894:- | gene-YDR196C_CBS1585 | rna-NM_001180504.3_CBS1585 | cds-NP_010482.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:838172-838897:- | gene-YDR196C_CBS436 | rna-NM_001180504.3_CBS436 | cds-NP_010482.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:805976-806701:- | gene-YDR196C_CBS6412 | rna-NM_001180504.3_CBS6412 | cds-NP_010482.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:836520-837245:- | gene-YDR196C_CBS6413 | rna-NM_001180504.3_CBS6413 | cds-NP_010482.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:849106-849831:- | gene-YDR196C_CENPK1137D | rna-NM_001180504.3_CENPK1137D | cds-NP_010482.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:819561-820286:- | gene-YDR196C_EthanolRed | rna-NM_001180504.3_EthanolRed | cds-NP_010482.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:827773-828498:- | gene-YDR196C_FaliES1 | rna-NM_001180504.3_FaliES1 | cds-NP_010482.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:20856-21581:+ | gene-YDR196C_JAY291 | rna-NM_001180504.3_JAY291 | cds-NP_010482.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:836874-837599:- | gene-YDR196C_MUCL30387 | rna-NM_001180504.3_MUCL30387 | cds-NP_010482.3_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:825123-825848:- | gene-YDR196C_MUCL30388 | rna-NM_001180504.3_MUCL30388 | cds-NP_010482.3_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:810616-811341:- | gene-YDR196C_MUCL39482 | rna-NM_001180504.3_MUCL39482 | cds-NP_010482.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:749313-750038:- | gene-YDR196C_MUCL42920 | rna-NM_001180504.3_MUCL42920 | cds-NP_010482.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:850197-850922:- | gene-YDR196C_NCIM3186 | rna-NM_001180504.3_NCIM3186 | cds-NP_010482.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:813750-814475:- | gene-YDR196C_NCYC1407 | rna-NM_001180504.3_NCYC1407 | cds-NP_010482.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:830502-831227:- | gene-YDR196C_PE2H3 | rna-NM_001180504.3_PE2H3 | cds-NP_010482.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:829807-830532:- | gene-YDR196C_PE2H4 | rna-NM_001180504.3_PE2H4 | cds-NP_010482.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:850274-850999:- | gene-YDR196C_S288C | rna-NM_001180504.3_S288C | cds-NP_010482.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:195986-196711:- | gene-YDR196C_SA1 | rna-NM_001180504.3_SA1 | cds-NP_010482.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:825928-826653:- | gene-YDR196C_ThermosaccDry | rna-NM_001180504.3_ThermosaccDry | cds-NP_010482.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:841155-841880:- | gene-YDR196C_VR1 | rna-NM_001180504.3_VR1 | cds-NP_010482.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:88646-89371:- | gene-YDR196C_ZTW1 | rna-NM_001180504.3_ZTW1 | cds-NP_010482.3_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:830785-831510:- | gene-YDR196C_Sparadoxus | rna-NM_001180504.3_Sparadoxus | cds-NP_010482.3_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |