Gene name: CAB4
Reference locus (S288C): YGR277C
Gene biotype: protein_coding
Description: Phosphopantetheine adenylyltransferase; Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable pantetheine-phosphate adenylyltransferase (PPAT); PPAT catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; null mutant lethality is complemented by E. coli coaD (encoding PPAT) and by human COASY
Top 10 interactors (score): CAB2 (0.999); CAB5 (0.999); CAB3 (0.999); CAB1 (0.997); VHS3 (0.988); SIS2 (0.985); YGR273C (0.811); PAN5 (0.715); SLM2 (0.711); PAN6 (0.711); KTR4 (0.693); KES1 (0.681); RMA1 (0.675); VMA5 (0.672); IFA38 (0.661); HEM12 (0.651); ERG13 (0.635); ANR2 (0.616); YEA4 (0.608); GCD1 (0.605)
Homologues (species, bitscore): COASY (Homo sapiens, 115.5); Coasy (Mus musculus, 121.3); coasy (Danio rerio, 129.8); coasy (Xenopus tropicalis, 118.6); Ppat-Dpck (Drosophila melanogaster, 99.8); Y65B4A.8 (Caenorhabditis elegans, 112.8); COAD (Arabidopsis thaliana, 119.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:1011063-1011980:- | gene-YGR277C_AKU4011 | rna-NM_001181406.3_AKU4011 | cds-NP_011793.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000010.1:1861-2778:- | gene-YGR277C_BG1 | rna-NM_001181406.3_BG1 | cds-NP_011793.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:1019582-1020499:- | gene-YGR277C_Bruggeman | rna-NM_001181406.3_Bruggeman | cds-NP_011793.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:1019062-1019979:- | gene-YGR277C_CAT1 | rna-NM_001181406.3_CAT1 | cds-NP_011793.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:1013931-1014848:- | gene-YGR277C_CBS1585 | rna-NM_001181406.3_CBS1585 | cds-NP_011793.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:1017567-1018484:- | gene-YGR277C_CBS436 | rna-NM_001181406.3_CBS436 | cds-NP_011793.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:1004823-1005740:- | gene-YGR277C_CBS6412 | rna-NM_001181406.3_CBS6412 | cds-NP_011793.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:1010876-1011793:- | gene-YGR277C_CBS6413 | rna-NM_001181406.3_CBS6413 | cds-NP_011793.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1045375-1046292:- | gene-YGR277C_CENPK1137D | rna-NM_001181406.3_CENPK1137D | cds-NP_011793.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:998912-999829:- | gene-YGR277C_EthanolRed | rna-NM_001181406.3_EthanolRed | cds-NP_011793.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:1003718-1004635:- | gene-YGR277C_FaliES1 | rna-NM_001181406.3_FaliES1 | cds-NP_011793.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:25680-26597:+ | gene-YGR277C_JAY291 | rna-NM_001181406.3_JAY291 | cds-NP_011793.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:1017323-1018240:- | gene-YGR277C_MUCL30387 | rna-NM_001181406.3_MUCL30387 | cds-NP_011793.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:1015455-1016372:- | gene-YGR277C_MUCL30388 | rna-NM_001181406.3_MUCL30388 | cds-NP_011793.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:1009037-1009954:- | gene-YGR277C_MUCL39482 | rna-NM_001181406.3_MUCL39482 | cds-NP_011793.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:1026918-1027835:- | gene-YGR277C_MUCL42920 | rna-NM_001181406.3_MUCL42920 | cds-NP_011793.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1045644-1046561:- | gene-YGR277C_NCIM3186 | rna-NM_001181406.3_NCIM3186 | cds-NP_011793.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:1004668-1005585:- | gene-YGR277C_NCYC1407 | rna-NM_001181406.3_NCYC1407 | cds-NP_011793.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:1029871-1030788:- | gene-YGR277C_PE2H3 | rna-NM_001181406.3_PE2H3 | cds-NP_011793.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:1034710-1035627:- | gene-YGR277C_PE2H4 | rna-NM_001181406.3_PE2H4 | cds-NP_011793.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1045644-1046561:- | gene-YGR277C_S288C | rna-NM_001181406.3_S288C | cds-NP_011793.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000063.1:43866-44783:- | gene-YGR277C_SA1 | rna-NM_001181406.3_SA1 | cds-NP_011793.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:1024238-1025155:- | gene-YGR277C_ThermosaccDry | rna-NM_001181406.3_ThermosaccDry | cds-NP_011793.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1130042-1130959:- | gene-YGR277C_VR1 | rna-NM_001181406.3_VR1 | cds-NP_011793.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:325643-326561:- | gene-YGR277C_ZTW1 | rna-NM_001181406.3_ZTW1 | cds-NP_011793.3_ZTW1 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:1016329-1017255:- | gene-YGR277C_Sparadoxus | rna-NM_001181406.3_Sparadoxus | cds-NP_011793.3_Sparadoxus | 88.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |