Gene name: CAB3
Reference locus (S288C): YKL088W
Gene biotype: protein_coding
Description: Coenzyme A biosynthesis protein 3; Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis; subunits of the phosphopantothenoylcysteine decarboxylase (PPCDC) complex are: Cab3p, Sis2p, Vhs3p, while the subunits of the CoA-synthesizing protein complex (CoA-SPC) are: Cab2p, Cab3p, Cab4p, and Cab5p as well as Sis2p and Vhs3p; null mutant lethality is complemented by E. coli coaBC
Top 10 interactors (score): CAB2 (0.999); CAB4 (0.999); CAB5 (0.998); CAB1 (0.995); VHS3 (0.993); SIS2 (0.993); PPZ1 (0.95); CKA1 (0.819); CKA2 (0.803); UTP22 (0.79); CKB2 (0.79); CMS1 (0.774); CKB1 (0.741); PAN6 (0.738); HOT1 (0.729); MET12 (0.722); PPZ2 (0.707); NPY1 (0.685); PAN5 (0.679); ECM31 (0.665)
Homologues (species, bitscore): PPCDC (Homo sapiens, 144.1); Ppcdc (Mus musculus, 139.8); ppcdc (Danio rerio, 140.6); ppcdc (Xenopus tropicalis, 139.4); Ppcdc (Drosophila melanogaster, 130.6); F25H9.6 (Caenorhabditis elegans, 142.1); HAL3A (Arabidopsis thaliana, 143.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:261840-263555:+ | gene-YKL088W_AKU4011 | rna-NM_001179654.1_AKU4011 | cds-NP_012835.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:238971-240686:+ | gene-YKL088W_BG1 | rna-NM_001179654.1_BG1 | cds-NP_012835.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:280013-281728:+ | gene-YKL088W_Bruggeman | rna-NM_001179654.1_Bruggeman | cds-NP_012835.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:274816-276531:+ | gene-YKL088W_CAT1 | rna-NM_001179654.1_CAT1 | cds-NP_012835.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:274082-275797:+ | gene-YKL088W_CBS1585 | rna-NM_001179654.1_CBS1585 | cds-NP_012835.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:272676-274391:+ | gene-YKL088W_CBS436 | rna-NM_001179654.1_CBS436 | cds-NP_012835.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:258710-260425:+ | gene-YKL088W_CBS6412 | rna-NM_001179654.1_CBS6412 | cds-NP_012835.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:274538-276253:+ | gene-YKL088W_CBS6413 | rna-NM_001179654.1_CBS6413 | cds-NP_012835.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:274922-276637:+ | gene-YKL088W_CENPK1137D | rna-NM_001179654.1_CENPK1137D | cds-NP_012835.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:272534-274249:+ | gene-YKL088W_EthanolRed | rna-NM_001179654.1_EthanolRed | cds-NP_012835.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:273347-275062:+ | gene-YKL088W_FaliES1 | rna-NM_001179654.1_FaliES1 | cds-NP_012835.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:95680-97395:+ | gene-YKL088W_JAY291 | rna-NM_001179654.1_JAY291 | cds-NP_012835.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:281812-283527:+ | gene-YKL088W_MUCL30387 | rna-NM_001179654.1_MUCL30387 | cds-NP_012835.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:276208-277923:+ | gene-YKL088W_MUCL30388 | rna-NM_001179654.1_MUCL30388 | cds-NP_012835.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:273867-275582:+ | gene-YKL088W_MUCL39482 | rna-NM_001179654.1_MUCL39482 | cds-NP_012835.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:278502-280217:+ | gene-YKL088W_MUCL42920 | rna-NM_001179654.1_MUCL42920 | cds-NP_012835.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:275272-276987:+ | gene-YKL088W_NCIM3186 | rna-NM_001179654.1_NCIM3186 | cds-NP_012835.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:274061-275776:+ | gene-YKL088W_NCYC1407 | rna-NM_001179654.1_NCYC1407 | cds-NP_012835.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:281152-282867:+ | gene-YKL088W_PE2H3 | rna-NM_001179654.1_PE2H3 | cds-NP_012835.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:277439-279154:+ | gene-YKL088W_PE2H4 | rna-NM_001179654.1_PE2H4 | cds-NP_012835.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:275283-276998:+ | gene-YKL088W_S288C | rna-NM_001179654.1_S288C | cds-NP_012835.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:191412-193127:+ | gene-YKL088W_SA1 | rna-NM_001179654.1_SA1 | cds-NP_012835.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:274052-275767:+ | gene-YKL088W_ThermosaccDry | rna-NM_001179654.1_ThermosaccDry | cds-NP_012835.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:273413-275128:+ | gene-YKL088W_VR1 | rna-NM_001179654.1_VR1 | cds-NP_012835.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:272619-274334:+ | gene-YKL088W_ZTW1 | rna-NM_001179654.1_ZTW1 | cds-NP_012835.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:289622-291493:+ | gene-YKL088W_Sparadoxus | rna-NM_001179654.1_Sparadoxus | cds-NP_012835.1_Sparadoxus | 81.0 | 99.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |