Gene name: CAB2
Reference locus (S288C): YIL083C
Gene biotype: protein_coding
Description: Phosphopantothenate--cysteine ligase CAB2; Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by human homolog PPCS and by E. coli coaBC (encoding a bifunctional enzyme with PPCS activity)
Top 10 interactors (score): CAB3 (0.999); CAB4 (0.999); CAB5 (0.999); CAB1 (0.998); VHS3 (0.987); SIS2 (0.985); PAN6 (0.959); IRC7 (0.872); MET17 (0.823); MCY1 (0.82); YPL238C (0.813); CYS3 (0.802); STR3 (0.802); AAT1 (0.8); AAT2 (0.8); FEN2 (0.743); PAN5 (0.736); ECM31 (0.725); SLM2 (0.71); RMA1 (0.701)
Homologues (species, bitscore): PPCS (Homo sapiens, 186.8); Ppcs (Mus musculus, 183.0); ppcs (Danio rerio, 212.2); ppcs (Xenopus tropicalis, 204.5); Ppcs (Drosophila melanogaster, 218.4); Y71H2AM.6 (Caenorhabditis elegans, 198.4); COAB (Arabidopsis thaliana, 193.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:205658-206755:- | gene-YIL083C_AKU4011 | rna-NM_001179431.2_AKU4011 | cds-NP_012183.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:67594-68691:- | gene-YIL083C_BG1 | rna-NM_001179431.2_BG1 | cds-NP_012183.2_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:210827-211924:- | gene-YIL083C_Bruggeman | rna-NM_001179431.2_Bruggeman | cds-NP_012183.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:201359-202456:- | gene-YIL083C_CAT1 | rna-NM_001179431.2_CAT1 | cds-NP_012183.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:205229-206326:- | gene-YIL083C_CBS1585 | rna-NM_001179431.2_CBS1585 | cds-NP_012183.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:195851-196948:- | gene-YIL083C_CBS436 | rna-NM_001179431.2_CBS436 | cds-NP_012183.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:202606-203703:- | gene-YIL083C_CBS6412 | rna-NM_001179431.2_CBS6412 | cds-NP_012183.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:197149-198246:- | gene-YIL083C_CBS6413 | rna-NM_001179431.2_CBS6413 | cds-NP_012183.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:194891-195988:- | gene-YIL083C_CENPK1137D | rna-NM_001179431.2_CENPK1137D | cds-NP_012183.2_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:189953-191050:- | gene-YIL083C_EthanolRed | rna-NM_001179431.2_EthanolRed | cds-NP_012183.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:206859-207956:- | gene-YIL083C_FaliES1 | rna-NM_001179431.2_FaliES1 | cds-NP_012183.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000025.1:21546-22643:+ | gene-YIL083C_JAY291 | rna-NM_001179431.2_JAY291 | cds-NP_012183.2_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:209292-210389:- | gene-YIL083C_MUCL30387 | rna-NM_001179431.2_MUCL30387 | cds-NP_012183.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:205901-206998:- | gene-YIL083C_MUCL30388 | rna-NM_001179431.2_MUCL30388 | cds-NP_012183.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:206076-207173:- | gene-YIL083C_MUCL39482 | rna-NM_001179431.2_MUCL39482 | cds-NP_012183.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:209438-210535:- | gene-YIL083C_MUCL42920 | rna-NM_001179431.2_MUCL42920 | cds-NP_012183.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:203556-204653:- | gene-YIL083C_NCIM3186 | rna-NM_001179431.2_NCIM3186 | cds-NP_012183.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:210353-211450:- | gene-YIL083C_NCYC1407 | rna-NM_001179431.2_NCYC1407 | cds-NP_012183.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:204340-205437:- | gene-YIL083C_PE2H3 | rna-NM_001179431.2_PE2H3 | cds-NP_012183.2_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:198714-199811:- | gene-YIL083C_PE2H4 | rna-NM_001179431.2_PE2H4 | cds-NP_012183.2_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:203556-204653:- | gene-YIL083C_S288C | rna-NM_001179431.2_S288C | cds-NP_012183.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000111.1:993-2090:+ | gene-YIL083C_SA1 | rna-NM_001179431.2_SA1 | cds-NP_012183.2_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:205524-206621:- | gene-YIL083C_ThermosaccDry | rna-NM_001179431.2_ThermosaccDry | cds-NP_012183.2_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:202405-203502:- | gene-YIL083C_VR1 | rna-NM_001179431.2_VR1 | cds-NP_012183.2_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:179789-180886:- | gene-YIL083C_ZTW1 | rna-NM_001179431.2_ZTW1 | cds-NP_012183.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:203556-204653:- | gene-YIL083C_Sparadoxus | rna-NM_001179431.2_Sparadoxus | cds-NP_012183.2_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |