Gene name: BXI1
Reference locus (S288C): YNL305C
Gene biotype: protein_coding
Description: Bax inhibitor 1; Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p
Top 10 interactors (score): NMA111 (0.96); MCA1 (0.948); AIF1 (0.878); KEX1 (0.843); YBR241C (0.819); NUC1 (0.816); FIS1 (0.815); FYV10 (0.814); NDI1 (0.79); ATG33 (0.731); NNR1 (0.728); DNM1 (0.718); HSP42 (0.71); SDS24 (0.694); TMA19 (0.693); SUI1 (0.664); CPR5 (0.655); YGR017W (0.65); ORM2 (0.647); TFS1 (0.625)
Homologues (species, bitscore): TMBIM1 (Homo sapiens, 82.4); Tmbim4 (Mus musculus, 86.7); zgc:136572 (Danio rerio, 89.0); tmbim4 (Xenopus tropicalis, 95.1); CG3814 (Drosophila melanogaster, 90.9); tag-120 (Caenorhabditis elegans, 69.7); AT4G02690 (Arabidopsis thaliana, 63.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:52695-53591:- | gene-YNL305C_AKU4011 | rna-NM_001183143.1_AKU4011 | cds-NP_014094.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000074.1:37053-37946:+ | gene-YNL305C_BG1 | rna-NM_001183143.1_BG1 | cds-NP_014094.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:62034-62927:- | gene-YNL305C_Bruggeman | rna-NM_001183143.1_Bruggeman | cds-NP_014094.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:64650-65543:- | gene-YNL305C_CAT1 | rna-NM_001183143.1_CAT1 | cds-NP_014094.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:53027-53923:- | gene-YNL305C_CBS1585 | rna-NM_001183143.1_CBS1585 | cds-NP_014094.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:53519-54412:- | gene-YNL305C_CBS436 | rna-NM_001183143.1_CBS436 | cds-NP_014094.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:49686-50582:- | gene-YNL305C_CBS6412 | rna-NM_001183143.1_CBS6412 | cds-NP_014094.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:49875-50771:- | gene-YNL305C_CBS6413 | rna-NM_001183143.1_CBS6413 | cds-NP_014094.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:52725-53618:- | gene-YNL305C_CENPK1137D | rna-NM_001183143.1_CENPK1137D | cds-NP_014094.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:49717-50613:- | gene-YNL305C_EthanolRed | rna-NM_001183143.1_EthanolRed | cds-NP_014094.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:50616-51512:- | gene-YNL305C_FaliES1 | rna-NM_001183143.1_FaliES1 | cds-NP_014094.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000390.1:4009-4902:+ | gene-YNL305C_JAY291 | rna-NM_001183143.1_JAY291 | cds-NP_014094.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:62289-63185:- | gene-YNL305C_MUCL30387 | rna-NM_001183143.1_MUCL30387 | cds-NP_014094.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:55320-56216:- | gene-YNL305C_MUCL30388 | rna-NM_001183143.1_MUCL30388 | cds-NP_014094.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:50663-51559:- | gene-YNL305C_MUCL39482 | rna-NM_001183143.1_MUCL39482 | cds-NP_014094.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:52355-53248:- | gene-YNL305C_MUCL42920 | rna-NM_001183143.1_MUCL42920 | cds-NP_014094.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:58867-59760:- | gene-YNL305C_NCIM3186 | rna-NM_001183143.1_NCIM3186 | cds-NP_014094.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:51995-52891:- | gene-YNL305C_NCYC1407 | rna-NM_001183143.1_NCYC1407 | cds-NP_014094.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:49197-50090:- | gene-YNL305C_PE2H3 | rna-NM_001183143.1_PE2H3 | cds-NP_014094.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:48585-49478:- | gene-YNL305C_PE2H4 | rna-NM_001183143.1_PE2H4 | cds-NP_014094.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:58898-59791:- | gene-YNL305C_S288C | rna-NM_001183143.1_S288C | cds-NP_014094.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000052.1:37438-38331:+ | gene-YNL305C_SA1 | rna-NM_001183143.1_SA1 | cds-NP_014094.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:51473-52369:- | gene-YNL305C_ThermosaccDry | rna-NM_001183143.1_ThermosaccDry | cds-NP_014094.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:64012-64908:- | gene-YNL305C_VR1 | rna-NM_001183143.1_VR1 | cds-NP_014094.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000029.1:42689-43585:- | gene-YNL305C_ZTW1 | rna-NM_001183143.1_ZTW1 | cds-NP_014094.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:60717-61613:- | gene-YNL305C_Sparadoxus | rna-NM_001183143.1_Sparadoxus | cds-NP_014094.1_Sparadoxus | 88.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |