Gene name: BUR6
Reference locus (S288C): YER159C
Gene biotype: protein_coding
Description: Subunit of a heterodimeric NC2 transcription regulator complex; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha; complex also includes Ncb2p; bur6 ncb2 double mutation is functionally complemented by coexpression of human DRAP1 and DR1, although the single bur6 mutation is not complemented by its ortholog DRAP1
Top 10 interactors (score): NCB2 (0.999); SPT15 (0.994); MOT1 (0.983); SUA7 (0.867); HAP3 (0.864); UBP14 (0.76); YDR509W (0.748); TOA1 (0.694); HAP5 (0.674); TAF9 (0.669); MRPL31 (0.65); TAF11 (0.641); DBP5 (0.636); TFB3 (0.588); SPT3 (0.578); SRF1 (0.574); YJL009W (0.568); O0508 (0.568); RPB7 (0.556); TAF1 (0.531)
Homologues (species, bitscore): DRAP1 (Homo sapiens, 79.3); Drap1 (Mus musculus, 79.0); drap1 (Danio rerio, 77.4); drap1 (Xenopus tropicalis, 71.2); NC2alpha (Drosophila melanogaster, 75.5); drap-1 (Caenorhabditis elegans, 60.8); NF-YC11 (Arabidopsis thaliana, 72.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:478661-479089:- | gene-YER159C_AKU4011 | rna-NM_001179049.3_AKU4011 | cds-NP_011086.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000176.1:53909-54337:+ | gene-YER159C_BG1 | rna-NM_001179049.3_BG1 | cds-NP_011086.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:491384-491812:- | gene-YER159C_Bruggeman | rna-NM_001179049.3_Bruggeman | cds-NP_011086.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:477827-478255:- | gene-YER159C_CAT1 | rna-NM_001179049.3_CAT1 | cds-NP_011086.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:478471-478899:- | gene-YER159C_CBS1585 | rna-NM_001179049.3_CBS1585 | cds-NP_011086.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:482323-482751:- | gene-YER159C_CBS436 | rna-NM_001179049.3_CBS436 | cds-NP_011086.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:476989-477417:- | gene-YER159C_CBS6412 | rna-NM_001179049.3_CBS6412 | cds-NP_011086.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:485025-485453:- | gene-YER159C_CBS6413 | rna-NM_001179049.3_CBS6413 | cds-NP_011086.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:489303-489731:- | gene-YER159C_CENPK1137D | rna-NM_001179049.3_CENPK1137D | cds-NP_011086.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:484970-485398:- | gene-YER159C_EthanolRed | rna-NM_001179049.3_EthanolRed | cds-NP_011086.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:485556-485984:- | gene-YER159C_FaliES1 | rna-NM_001179049.3_FaliES1 | cds-NP_011086.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000111.1:507-935:+ | gene-YER159C_JAY291 | rna-NM_001179049.3_JAY291 | cds-NP_011086.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:478721-479149:- | gene-YER159C_MUCL30387 | rna-NM_001179049.3_MUCL30387 | cds-NP_011086.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:481625-482053:- | gene-YER159C_MUCL30388 | rna-NM_001179049.3_MUCL30388 | cds-NP_011086.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:474428-474856:- | gene-YER159C_MUCL39482 | rna-NM_001179049.3_MUCL39482 | cds-NP_011086.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:487971-488399:- | gene-YER159C_MUCL42920 | rna-NM_001179049.3_MUCL42920 | cds-NP_011086.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:491529-491957:- | gene-YER159C_NCIM3186 | rna-NM_001179049.3_NCIM3186 | cds-NP_011086.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:483894-484322:- | gene-YER159C_NCYC1407 | rna-NM_001179049.3_NCYC1407 | cds-NP_011086.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:499604-500032:- | gene-YER159C_PE2H3 | rna-NM_001179049.3_PE2H3 | cds-NP_011086.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:489545-489973:- | gene-YER159C_PE2H4 | rna-NM_001179049.3_PE2H4 | cds-NP_011086.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:491530-491958:- | gene-YER159C_S288C | rna-NM_001179049.3_S288C | cds-NP_011086.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000030.1:49433-49861:- | gene-YER159C_SA1 | rna-NM_001179049.3_SA1 | cds-NP_011086.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:486356-486784:- | gene-YER159C_ThermosaccDry | rna-NM_001179049.3_ThermosaccDry | cds-NP_011086.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:479481-479909:- | gene-YER159C_VR1 | rna-NM_001179049.3_VR1 | cds-NP_011086.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:487236-487664:- | gene-YER159C_Sparadoxus | rna-NM_001179049.3_Sparadoxus | cds-NP_011086.3_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |