Gene name: BUD32
Reference locus (S288C): YGR262C
Gene biotype: protein_coding
Description: Protein kinase; component of the EKC/KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; Pyrococcus Bud32 ortholog functions as a P-loop ATPase rather than a protein kinase in the context of the complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; mutation is functionally complemented by human TP53RK
Top 10 interactors (score): KAE1 (0.999); CGI121 (0.999); GON7 (0.996); QRI7 (0.99); PCC1 (0.99); GRX4 (0.979); SUA5 (0.924); GRX3 (0.799); MES1 (0.769); RIO1 (0.727); MET3 (0.707); IKS1 (0.692); ERV41 (0.672); YDL057W (0.672); SCY1 (0.671); CBK1 (0.671); YDL009C (0.67); PKP1 (0.655); MCP2 (0.653); RNH201 (0.652)
Homologues (species, bitscore): TP53RK (Homo sapiens, 126.3); Trp53rk (Mus musculus, 132.9); tp53rk (Danio rerio, 129.4); tp53rk (Xenopus tropicalis, 120.9); Prpk (Drosophila melanogaster, 121.7); F52C12.6 (Caenorhabditis elegans, 122.1); AT5G26110 (Arabidopsis thaliana, 121.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:982415-983200:- | gene-YGR262C_AKU4011 | rna-NM_001181391.1_AKU4011 | cds-NP_011778.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:262412-263197:- | gene-YGR262C_BG1 | rna-NM_001181391.1_BG1 | cds-NP_011778.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:990925-991710:- | gene-YGR262C_Bruggeman | rna-NM_001181391.1_Bruggeman | cds-NP_011778.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:990118-990903:- | gene-YGR262C_CAT1 | rna-NM_001181391.1_CAT1 | cds-NP_011778.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:985285-986070:- | gene-YGR262C_CBS1585 | rna-NM_001181391.1_CBS1585 | cds-NP_011778.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:988905-989690:- | gene-YGR262C_CBS436 | rna-NM_001181391.1_CBS436 | cds-NP_011778.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:976175-976960:- | gene-YGR262C_CBS6412 | rna-NM_001181391.1_CBS6412 | cds-NP_011778.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:982230-983015:- | gene-YGR262C_CBS6413 | rna-NM_001181391.1_CBS6413 | cds-NP_011778.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1016646-1017431:- | gene-YGR262C_CENPK1137D | rna-NM_001181391.1_CENPK1137D | cds-NP_011778.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:970255-971040:- | gene-YGR262C_EthanolRed | rna-NM_001181391.1_EthanolRed | cds-NP_011778.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:975061-975846:- | gene-YGR262C_FaliES1 | rna-NM_001181391.1_FaliES1 | cds-NP_011778.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:54464-55249:+ | gene-YGR262C_JAY291 | rna-NM_001181391.1_JAY291 | cds-NP_011778.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:988666-989451:- | gene-YGR262C_MUCL30387 | rna-NM_001181391.1_MUCL30387 | cds-NP_011778.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:986798-987583:- | gene-YGR262C_MUCL30388 | rna-NM_001181391.1_MUCL30388 | cds-NP_011778.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:980391-981176:- | gene-YGR262C_MUCL39482 | rna-NM_001181391.1_MUCL39482 | cds-NP_011778.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:998253-999038:- | gene-YGR262C_MUCL42920 | rna-NM_001181391.1_MUCL42920 | cds-NP_011778.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1016974-1017759:- | gene-YGR262C_NCIM3186 | rna-NM_001181391.1_NCIM3186 | cds-NP_011778.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:976020-976805:- | gene-YGR262C_NCYC1407 | rna-NM_001181391.1_NCYC1407 | cds-NP_011778.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:1001205-1001990:- | gene-YGR262C_PE2H3 | rna-NM_001181391.1_PE2H3 | cds-NP_011778.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:1006044-1006829:- | gene-YGR262C_PE2H4 | rna-NM_001181391.1_PE2H4 | cds-NP_011778.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1016974-1017759:- | gene-YGR262C_S288C | rna-NM_001181391.1_S288C | cds-NP_011778.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000063.1:15196-15981:- | gene-YGR262C_SA1 | rna-NM_001181391.1_SA1 | cds-NP_011778.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:995581-996366:- | gene-YGR262C_ThermosaccDry | rna-NM_001181391.1_ThermosaccDry | cds-NP_011778.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1101362-1102147:- | gene-YGR262C_VR1 | rna-NM_001181391.1_VR1 | cds-NP_011778.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:296994-297779:- | gene-YGR262C_ZTW1 | rna-NM_001181391.1_ZTW1 | cds-NP_011778.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:987622-988407:- | gene-YGR262C_Sparadoxus | rna-NM_001181391.1_Sparadoxus | cds-NP_011778.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |