Gene name: BUD2
Reference locus (S288C): YKL092C
Gene biotype: protein_coding
Description: Inhibitory regulator protein BUD2/CLA2; GTPase activating factor for Rsr1p/Bud1p; plays a role in spindle position checkpoint distinct from its role in bud site selection; required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types; contains two PH-like domains
Top 10 interactors (score): RSR1 (0.996); BUD5 (0.981); CDC42 (0.853); BUD4 (0.85); BUD3 (0.845); BEM1 (0.795); BUD9 (0.78); BUD6 (0.774); CDC24 (0.773); BUD8 (0.773); AXL2 (0.772); ARF3 (0.756); AXL1 (0.751); RAX2 (0.749); RAS2 (0.741); RAX1 (0.738); CLN2 (0.722); SPA2 (0.719); GIC1 (0.717); MBR1 (0.717)
Homologues (species, bitscore): RASAL2 (Homo sapiens, 126.7); Rasal2 (Mus musculus, 128.3); rasa1b (Danio rerio, 122.1); rasal2 (Xenopus tropicalis, 122.5); CG42684 (Drosophila melanogaster, 123.6); gap-2 (Caenorhabditis elegans, 124.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:252703-256017:- | gene-YKL092C_AKU4011 | rna-NM_001179658.1_AKU4011 | cds-NP_012831.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:229824-233138:- | gene-YKL092C_BG1 | rna-NM_001179658.1_BG1 | cds-NP_012831.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:270876-274190:- | gene-YKL092C_Bruggeman | rna-NM_001179658.1_Bruggeman | cds-NP_012831.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:265669-268983:- | gene-YKL092C_CAT1 | rna-NM_001179658.1_CAT1 | cds-NP_012831.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:264945-268259:- | gene-YKL092C_CBS1585 | rna-NM_001179658.1_CBS1585 | cds-NP_012831.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:263531-266845:- | gene-YKL092C_CBS436 | rna-NM_001179658.1_CBS436 | cds-NP_012831.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:249573-252887:- | gene-YKL092C_CBS6412 | rna-NM_001179658.1_CBS6412 | cds-NP_012831.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:265401-268715:- | gene-YKL092C_CBS6413 | rna-NM_001179658.1_CBS6413 | cds-NP_012831.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:265785-269099:- | gene-YKL092C_CENPK1137D | rna-NM_001179658.1_CENPK1137D | cds-NP_012831.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:263397-266711:- | gene-YKL092C_EthanolRed | rna-NM_001179658.1_EthanolRed | cds-NP_012831.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:264210-267524:- | gene-YKL092C_FaliES1 | rna-NM_001179658.1_FaliES1 | cds-NP_012831.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:86533-89847:- | gene-YKL092C_JAY291 | rna-NM_001179658.1_JAY291 | cds-NP_012831.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:272675-275989:- | gene-YKL092C_MUCL30387 | rna-NM_001179658.1_MUCL30387 | cds-NP_012831.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:267071-270385:- | gene-YKL092C_MUCL30388 | rna-NM_001179658.1_MUCL30388 | cds-NP_012831.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:264730-268044:- | gene-YKL092C_MUCL39482 | rna-NM_001179658.1_MUCL39482 | cds-NP_012831.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:269359-272673:- | gene-YKL092C_MUCL42920 | rna-NM_001179658.1_MUCL42920 | cds-NP_012831.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:266134-269448:- | gene-YKL092C_NCIM3186 | rna-NM_001179658.1_NCIM3186 | cds-NP_012831.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:264924-268238:- | gene-YKL092C_NCYC1407 | rna-NM_001179658.1_NCYC1407 | cds-NP_012831.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:272008-275322:- | gene-YKL092C_PE2H3 | rna-NM_001179658.1_PE2H3 | cds-NP_012831.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:268295-271609:- | gene-YKL092C_PE2H4 | rna-NM_001179658.1_PE2H4 | cds-NP_012831.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:266145-269459:- | gene-YKL092C_S288C | rna-NM_001179658.1_S288C | cds-NP_012831.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:182264-185578:- | gene-YKL092C_SA1 | rna-NM_001179658.1_SA1 | cds-NP_012831.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:264915-268229:- | gene-YKL092C_ThermosaccDry | rna-NM_001179658.1_ThermosaccDry | cds-NP_012831.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:264269-267583:- | gene-YKL092C_VR1 | rna-NM_001179658.1_VR1 | cds-NP_012831.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:263475-266789:- | gene-YKL092C_ZTW1 | rna-NM_001179658.1_ZTW1 | cds-NP_012831.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:280461-283775:- | gene-YKL092C_Sparadoxus | rna-NM_001179658.1_Sparadoxus | cds-NP_012831.1_Sparadoxus | 88.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |