Gene name: BUB3
Reference locus (S288C): YOR026W
Gene biotype: protein_coding
Description: Cell cycle arrest protein BUB3; Kinetochore checkpoint WD40 repeat protein; localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p; functions at kinetochore to activate APC/C-Cdc20p for normal mitotic progression
Top 10 interactors (score): MAD3 (0.999); NDC80 (0.999); CDC20 (0.999); MAD2 (0.999); BUB1 (0.999); CDC23 (0.998); SPC105 (0.998); IPL1 (0.995); MAD1 (0.995); MPS1 (0.991); CDC27 (0.991); ESP1 (0.99); SMC1 (0.99); STU2 (0.986); APC4 (0.985); APC11 (0.972); DOC1 (0.97); PAC1 (0.969); BUB2 (0.968); CDH1 (0.967)
Homologues (species, bitscore): BUB3 (Homo sapiens, 129.8); Bub3 (Mus musculus, 130.2); bub3 (Danio rerio, 133.3); bub3 (Xenopus tropicalis, 119.0); Bub3 (Drosophila melanogaster, 114.4); bub-3 (Caenorhabditis elegans, 123.6); BUB3.1 (Arabidopsis thaliana, 114.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:363992-365017:+ | gene-YOR026W_AKU4011 | rna-NM_001183445.1_AKU4011 | cds-NP_014669.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:179574-180599:+ | gene-YOR026W_BG1 | rna-NM_001183445.1_BG1 | cds-NP_014669.1_BG1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:366736-367761:+ | gene-YOR026W_Bruggeman | rna-NM_001183445.1_Bruggeman | cds-NP_014669.1_Bruggeman | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:364892-365917:+ | gene-YOR026W_CAT1 | rna-NM_001183445.1_CAT1 | cds-NP_014669.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:358684-359709:+ | gene-YOR026W_CBS1585 | rna-NM_001183445.1_CBS1585 | cds-NP_014669.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:363043-364068:+ | gene-YOR026W_CBS436 | rna-NM_001183445.1_CBS436 | cds-NP_014669.1_CBS436 | 98.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:358037-359062:+ | gene-YOR026W_CBS6412 | rna-NM_001183445.1_CBS6412 | cds-NP_014669.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:365413-366438:+ | gene-YOR026W_CBS6413 | rna-NM_001183445.1_CBS6413 | cds-NP_014669.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:379664-380689:+ | gene-YOR026W_CENPK1137D | rna-NM_001183445.1_CENPK1137D | cds-NP_014669.1_CENPK1137D | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:360694-361719:+ | gene-YOR026W_EthanolRed | rna-NM_001183445.1_EthanolRed | cds-NP_014669.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:364042-365067:+ | gene-YOR026W_FaliES1 | rna-NM_001183445.1_FaliES1 | cds-NP_014669.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:34690-35715:+ | gene-YOR026W_JAY291 | rna-NM_001183445.1_JAY291 | cds-NP_014669.1_JAY291 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:371125-372150:+ | gene-YOR026W_MUCL30387 | rna-NM_001183445.1_MUCL30387 | cds-NP_014669.1_MUCL30387 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:374558-375583:+ | gene-YOR026W_MUCL30388 | rna-NM_001183445.1_MUCL30388 | cds-NP_014669.1_MUCL30388 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:366167-367192:+ | gene-YOR026W_MUCL39482 | rna-NM_001183445.1_MUCL39482 | cds-NP_014669.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:380982-382007:+ | gene-YOR026W_MUCL42920 | rna-NM_001183445.1_MUCL42920 | cds-NP_014669.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:379670-380695:+ | gene-YOR026W_NCIM3186 | rna-NM_001183445.1_NCIM3186 | cds-NP_014669.1_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:372869-373894:+ | gene-YOR026W_NCYC1407 | rna-NM_001183445.1_NCYC1407 | cds-NP_014669.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:371710-372735:+ | gene-YOR026W_PE2H3 | rna-NM_001183445.1_PE2H3 | cds-NP_014669.1_PE2H3 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:382089-383114:+ | gene-YOR026W_PE2H4 | rna-NM_001183445.1_PE2H4 | cds-NP_014669.1_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:379781-380806:+ | gene-YOR026W_S288C | rna-NM_001183445.1_S288C | cds-NP_014669.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:347576-348601:+ | gene-YOR026W_SA1 | rna-NM_001183445.1_SA1 | cds-NP_014669.1_SA1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:362582-363607:+ | gene-YOR026W_ThermosaccDry | rna-NM_001183445.1_ThermosaccDry | cds-NP_014669.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:363471-364496:+ | gene-YOR026W_VR1 | rna-NM_001183445.1_VR1 | cds-NP_014669.1_VR1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:97211-98236:+ | gene-YOR026W_ZTW1 | rna-NM_001183445.1_ZTW1 | cds-NP_014669.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:369749-370774:+ | gene-YOR026W_Sparadoxus | rna-NM_001183445.1_Sparadoxus | cds-NP_014669.1_Sparadoxus | 87.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |