BUB2 (YMR055C)


Gene profile

Gene name: BUB2
Reference locus (S288C): YMR055C
Gene biotype: protein_coding

Description: Mitotic check point protein BUB2; Mitotic exit network regulator; forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage; Belongs to the BUB2 family

Top 10 interactors (score): TEM1 (0.999); BFA1 (0.999); CDC15 (0.996); CDC5 (0.995); KIN4 (0.995); LTE1 (0.991); MAD2 (0.991); NUD1 (0.989); CDC14 (0.981); BUB1 (0.981); DYN1 (0.973); KAR9 (0.972); BUB3 (0.968); MPS1 (0.967); MOB1 (0.964); DBF2 (0.957); MAD3 (0.955); CDC16 (0.945); GIC1 (0.941); MAD1 (0.938)

Homologues (species, bitscore): TBC1D8 (Homo sapiens, 53.5); Tbc1d8 (Mus musculus, 55.5); TBC1D10C (Danio rerio, 50.4); tbc1d8 (Xenopus tropicalis, 54.3); GAPsec (Drosophila melanogaster, 52.4); tbck-1 (Caenorhabditis elegans, 63.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:423829-424749:- gene-YMR055C_AKU4011 rna-NM_001182553.1_AKU4011 cds-NP_013771.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:118033-118953:+ gene-YMR055C_BG1 rna-NM_001182553.1_BG1 cds-NP_013771.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:365996-366916:- gene-YMR055C_Bruggeman rna-NM_001182553.1_Bruggeman cds-NP_013771.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:366323-367243:- gene-YMR055C_CAT1 rna-NM_001182553.1_CAT1 cds-NP_013771.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:356771-357691:- gene-YMR055C_CBS1585 rna-NM_001182553.1_CBS1585 cds-NP_013771.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:362322-363242:- gene-YMR055C_CBS436 rna-NM_001182553.1_CBS436 cds-NP_013771.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:470172-471092:- gene-YMR055C_CBS6412 rna-NM_001182553.1_CBS6412 cds-NP_013771.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:356026-356946:- gene-YMR055C_CBS6413 rna-NM_001182553.1_CBS6413 cds-NP_013771.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:380232-381152:- gene-YMR055C_CENPK1137D rna-NM_001182553.1_CENPK1137D cds-NP_013771.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:356620-357540:- gene-YMR055C_EthanolRed rna-NM_001182553.1_EthanolRed cds-NP_013771.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:359787-360707:- gene-YMR055C_FaliES1 rna-NM_001182553.1_FaliES1 cds-NP_013771.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:76231-77151:+ gene-YMR055C_JAY291 rna-NM_001182553.1_JAY291 cds-NP_013771.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:361737-362657:- gene-YMR055C_MUCL30387 rna-NM_001182553.1_MUCL30387 cds-NP_013771.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:366405-367325:- gene-YMR055C_MUCL30388 rna-NM_001182553.1_MUCL30388 cds-NP_013771.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:357059-357979:- gene-YMR055C_MUCL39482 rna-NM_001182553.1_MUCL39482 cds-NP_013771.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:363718-364638:- gene-YMR055C_MUCL42920 rna-NM_001182553.1_MUCL42920 cds-NP_013771.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:386055-386975:- gene-YMR055C_NCIM3186 rna-NM_001182553.1_NCIM3186 cds-NP_013771.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:356970-357890:- gene-YMR055C_NCYC1407 rna-NM_001182553.1_NCYC1407 cds-NP_013771.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:362924-363844:- gene-YMR055C_PE2H3 rna-NM_001182553.1_PE2H3 cds-NP_013771.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:369019-369939:- gene-YMR055C_PE2H4 rna-NM_001182553.1_PE2H4 cds-NP_013771.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:386101-387021:- gene-YMR055C_S288C rna-NM_001182553.1_S288C cds-NP_013771.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:163106-164026:+ gene-YMR055C_SA1 rna-NM_001182553.1_SA1 cds-NP_013771.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:357593-358513:- gene-YMR055C_ThermosaccDry rna-NM_001182553.1_ThermosaccDry cds-NP_013771.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:367865-368785:- gene-YMR055C_VR1 rna-NM_001182553.1_VR1 cds-NP_013771.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:335870-336790:- gene-YMR055C_ZTW1 rna-NM_001182553.1_ZTW1 cds-NP_013771.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:369495-370415:- gene-YMR055C_Sparadoxus rna-NM_001182553.1_Sparadoxus cds-NP_013771.1_Sparadoxus 90.3 100.0 Verified 1 1 1 False True False False False

Additional files