Gene name: BTT1
Reference locus (S288C): YDR252W
Gene biotype: protein_coding
Description: Heterotrimeric nascent polypeptide-associated complex beta3 subunit; complex binds ribosomes via its beta-subunits in close proximity to nascent polypeptides; interacts with Caf130p of the CCR4-NOT complex; similar to human BTF3; BTT1 has a paralog, EGD1, that arose from the whole genome duplication
Top 10 interactors (score): EGD2 (0.999); RPL25 (0.997); RPL10 (0.985); RPS2 (0.984); RPL39 (0.983); CAF130 (0.981); RPS13 (0.98); RPS15 (0.974); RPL32 (0.972); RPP0 (0.972); RPL17A (0.965); CAF40 (0.964); EGD1 (0.96); CDC39 (0.958); CAF16 (0.956); NOT5 (0.951); RPL21A (0.936); CDC36 (0.936); RPL21B (0.936); RPL5 (0.935)
Homologues (species, bitscore): BTF3L4 (Homo sapiens, 66.6); Btf3l4 (Mus musculus, 66.6); btf3l4 (Danio rerio, 66.6); btf3l4 (Xenopus tropicalis, 65.9); bic (Drosophila melanogaster, 65.9); icd-1 (Caenorhabditis elegans, 61.6); BTF3 (Arabidopsis thaliana, 55.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:919741-920190:+ | gene-YDR252W_AKU4011 | rna-NM_001180560.1_AKU4011 | cds-NP_010538.1_AKU4011 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:205115-205564:- | gene-YDR252W_BG1 | rna-NM_001180560.1_BG1 | cds-NP_010538.1_BG1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:952070-952519:+ | gene-YDR252W_Bruggeman | rna-NM_001180560.1_Bruggeman | cds-NP_010538.1_Bruggeman | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:939355-939804:+ | gene-YDR252W_CAT1 | rna-NM_001180560.1_CAT1 | cds-NP_010538.1_CAT1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:910090-910539:+ | gene-YDR252W_CBS1585 | rna-NM_001180560.1_CBS1585 | cds-NP_010538.1_CBS1585 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:939649-940098:+ | gene-YDR252W_CBS436 | rna-NM_001180560.1_CBS436 | cds-NP_010538.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:906850-907299:+ | gene-YDR252W_CBS6412 | rna-NM_001180560.1_CBS6412 | cds-NP_010538.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:937944-938393:+ | gene-YDR252W_CBS6413 | rna-NM_001180560.1_CBS6413 | cds-NP_010538.1_CBS6413 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:962337-962786:+ | gene-YDR252W_CENPK1137D | rna-NM_001180560.1_CENPK1137D | cds-NP_010538.1_CENPK1137D | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:920409-920858:+ | gene-YDR252W_EthanolRed | rna-NM_001180560.1_EthanolRed | cds-NP_010538.1_EthanolRed | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:928611-929060:+ | gene-YDR252W_FaliES1 | rna-NM_001180560.1_FaliES1 | cds-NP_010538.1_FaliES1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000261.1:17145-17594:+ | gene-YDR252W_JAY291 | rna-NM_001180560.1_JAY291 | cds-NP_010538.1_JAY291 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:937968-938417:+ | gene-YDR252W_MUCL30387 | rna-NM_001180560.1_MUCL30387 | cds-NP_010538.1_MUCL30387 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:925998-926447:+ | gene-YDR252W_MUCL30388 | rna-NM_001180560.1_MUCL30388 | cds-NP_010538.1_MUCL30388 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:911495-911944:+ | gene-YDR252W_MUCL39482 | rna-NM_001180560.1_MUCL39482 | cds-NP_010538.1_MUCL39482 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:851259-851708:+ | gene-YDR252W_MUCL42920 | rna-NM_001180560.1_MUCL42920 | cds-NP_010538.1_MUCL42920 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:963335-963784:+ | gene-YDR252W_NCIM3186 | rna-NM_001180560.1_NCIM3186 | cds-NP_010538.1_NCIM3186 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:915164-915613:+ | gene-YDR252W_NCYC1407 | rna-NM_001180560.1_NCYC1407 | cds-NP_010538.1_NCYC1407 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:931422-931871:+ | gene-YDR252W_PE2H3 | rna-NM_001180560.1_PE2H3 | cds-NP_010538.1_PE2H3 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:936699-937148:+ | gene-YDR252W_PE2H4 | rna-NM_001180560.1_PE2H4 | cds-NP_010538.1_PE2H4 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:963412-963861:+ | gene-YDR252W_S288C | rna-NM_001180560.1_S288C | cds-NP_010538.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:169259-169708:+ | gene-YDR252W_SA1 | rna-NM_001180560.1_SA1 | cds-NP_010538.1_SA1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:926765-927214:+ | gene-YDR252W_ThermosaccDry | rna-NM_001180560.1_ThermosaccDry | cds-NP_010538.1_ThermosaccDry | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:942022-942471:+ | gene-YDR252W_VR1 | rna-NM_001180560.1_VR1 | cds-NP_010538.1_VR1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:189509-189958:+ | gene-YDR252W_ZTW1 | rna-NM_001180560.1_ZTW1 | cds-NP_010538.1_ZTW1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:932175-932624:+ | gene-YDR252W_Sparadoxus | rna-NM_001180560.1_Sparadoxus | cds-NP_010538.1_Sparadoxus | 87.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |