Gene name: BST1
Reference locus (S288C): YFL025C
Gene biotype: protein_coding
Description: GPI inositol deacylase of the endoplasmic reticulum (ER); negatively regulates COPII vesicle formation; prevents production of vesicles with defective subunits; required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules; functional ortholog of human PGAP1, mutation of which is associated with intellectual disability and encephalopathy
Top 10 interactors (score): GAA1 (0.989); GPI16 (0.988); GPI8 (0.986); GAB1 (0.984); GPI17 (0.982); PER1 (0.931); GPI10 (0.892); CNE1 (0.869); SPT14 (0.86); GPI14 (0.845); CDC1 (0.785); ROT2 (0.778); GPI2 (0.773); ERV25 (0.755); ERV14 (0.736); KEX1 (0.734); LAS21 (0.729); EMP24 (0.729); EPS1 (0.712); ERP1 (0.702)
Homologues (species, bitscore): PGAP1 (Homo sapiens, 171.4); Pgap1 (Mus musculus, 174.9); pgap1 (Danio rerio, 182.2); PGAP1 (Xenopus tropicalis, 136.7); CG3160 (Drosophila melanogaster, 129.4); T19B10.8 (Caenorhabditis elegans, 88.2); AT3G27325 (Arabidopsis thaliana, 158.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:80499-83588:- | gene-YFL025C_AKU4011 | rna-NM_001179941.1_AKU4011 | cds-NP_116628.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000089.1:10824-13913:- | gene-YFL025C_BG1 | rna-NM_001179941.1_BG1 | cds-NP_116628.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:79365-82454:- | gene-YFL025C_Bruggeman | rna-NM_001179941.1_Bruggeman | cds-NP_116628.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:84514-87603:- | gene-YFL025C_CAT1 | rna-NM_001179941.1_CAT1 | cds-NP_116628.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:81307-84396:- | gene-YFL025C_CBS1585 | rna-NM_001179941.1_CBS1585 | cds-NP_116628.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:54813-57902:- | gene-YFL025C_CBS436 | rna-NM_001179941.1_CBS436 | cds-NP_116628.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:81041-84130:- | gene-YFL025C_CBS6412 | rna-NM_001179941.1_CBS6412 | cds-NP_116628.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:83576-86665:- | gene-YFL025C_CBS6413 | rna-NM_001179941.1_CBS6413 | cds-NP_116628.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:80471-83560:- | gene-YFL025C_CENPK1137D | rna-NM_001179941.1_CENPK1137D | cds-NP_116628.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:79464-82553:- | gene-YFL025C_EthanolRed | rna-NM_001179941.1_EthanolRed | cds-NP_116628.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:81103-84192:- | gene-YFL025C_FaliES1 | rna-NM_001179941.1_FaliES1 | cds-NP_116628.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:89492-92581:- | gene-YFL025C_JAY291 | rna-NM_001179941.1_JAY291 | cds-NP_116628.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:81460-84549:- | gene-YFL025C_MUCL30387 | rna-NM_001179941.1_MUCL30387 | cds-NP_116628.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:79399-82488:- | gene-YFL025C_MUCL30388 | rna-NM_001179941.1_MUCL30388 | cds-NP_116628.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:79692-82781:- | gene-YFL025C_MUCL39482 | rna-NM_001179941.1_MUCL39482 | cds-NP_116628.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:77802-80891:- | gene-YFL025C_MUCL42920 | rna-NM_001179941.1_MUCL42920 | cds-NP_116628.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:84144-87233:- | gene-YFL025C_NCIM3186 | rna-NM_001179941.1_NCIM3186 | cds-NP_116628.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:80781-83870:- | gene-YFL025C_NCYC1407 | rna-NM_001179941.1_NCYC1407 | cds-NP_116628.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:100684-103773:- | gene-YFL025C_PE2H3 | rna-NM_001179941.1_PE2H3 | cds-NP_116628.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:100235-103324:- | gene-YFL025C_PE2H4 | rna-NM_001179941.1_PE2H4 | cds-NP_116628.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:84145-87234:- | gene-YFL025C_S288C | rna-NM_001179941.1_S288C | cds-NP_116628.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000117.1:8213-11302:- | gene-YFL025C_SA1 | rna-NM_001179941.1_SA1 | cds-NP_116628.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:80286-83375:- | gene-YFL025C_ThermosaccDry | rna-NM_001179941.1_ThermosaccDry | cds-NP_116628.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:88822-91911:- | gene-YFL025C_VR1 | rna-NM_001179941.1_VR1 | cds-NP_116628.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:10758-13846:- | gene-YFL025C_ZTW1 | rna-NM_001179941.1_ZTW1 | cds-NP_116628.1_ZTW1 | 99.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:104540-107626:- | gene-YFL025C_Sparadoxus | rna-NM_001179941.1_Sparadoxus | cds-NP_116628.1_Sparadoxus | 88.8 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |