BRX1 (YOL077C)


Gene profile

Gene name: BRX1
Reference locus (S288C): YOL077C
Gene biotype: protein_coding

Description: Ribosome biogenesis protein BRX1; Nucleolar protein; constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif

Top 10 interactors (score): RPF2 (0.999); NOC3 (0.999); YTM1 (0.999); SPB1 (0.999); NOP16 (0.999); NOP15 (0.999); RRS1 (0.999); RPF1 (0.999); MAK5 (0.999); NOP2 (0.999); NSA2 (0.999); NOG2 (0.999); NOP12 (0.999); IMP4 (0.999); HAS1 (0.999); NSA1 (0.999); NOP58 (0.999); RLP24 (0.999); DRS1 (0.999); RRP1 (0.999)

Homologues (species, bitscore): BRIX1 (Homo sapiens, 273.1); Brix1 (Mus musculus, 273.9); bxdc2 (Danio rerio, 278.5); brix1 (Xenopus tropicalis, 280.8); CG11583 (Drosophila melanogaster, 243.0); K12H4.3 (Caenorhabditis elegans, 232.6); AT3G15460 (Arabidopsis thaliana, 249.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:169488-170363:- gene-YOL077C_AKU4011 rna-NM_001183331.2_AKU4011 cds-NP_014565.2_AKU4011 99.7 100.0 Mismatch 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000172.1:134299-135174:- gene-YOL077C_BG1 rna-NM_001183331.2_BG1 cds-NP_014565.2_BG1 99.7 100.0 Mismatch 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:171174-172049:- gene-YOL077C_Bruggeman rna-NM_001183331.2_Bruggeman cds-NP_014565.2_Bruggeman 99.8 100.0 Mismatch 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:170666-171541:- gene-YOL077C_CAT1 rna-NM_001183331.2_CAT1 cds-NP_014565.2_CAT1 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:163881-164756:- gene-YOL077C_CBS1585 rna-NM_001183331.2_CBS1585 cds-NP_014565.2_CBS1585 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:169065-169940:- gene-YOL077C_CBS436 rna-NM_001183331.2_CBS436 cds-NP_014565.2_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:163809-164684:- gene-YOL077C_CBS6412 rna-NM_001183331.2_CBS6412 cds-NP_014565.2_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:170744-171619:- gene-YOL077C_CBS6413 rna-NM_001183331.2_CBS6413 cds-NP_014565.2_CBS6413 99.8 100.0 Mismatch 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:185603-186478:- gene-YOL077C_CENPK1137D rna-NM_001183331.2_CENPK1137D cds-NP_014565.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:166803-167678:- gene-YOL077C_EthanolRed rna-NM_001183331.2_EthanolRed cds-NP_014565.2_EthanolRed 99.8 100.0 Mismatch 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:169130-170005:- gene-YOL077C_FaliES1 rna-NM_001183331.2_FaliES1 cds-NP_014565.2_FaliES1 99.8 100.0 Mismatch 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:95532-96407:+ gene-YOL077C_JAY291 rna-NM_001183331.2_JAY291 cds-NP_014565.2_JAY291 99.7 100.0 Mismatch 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:174944-175819:- gene-YOL077C_MUCL30387 rna-NM_001183331.2_MUCL30387 cds-NP_014565.2_MUCL30387 99.6 100.0 Mismatch 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:178623-179498:- gene-YOL077C_MUCL30388 rna-NM_001183331.2_MUCL30388 cds-NP_014565.2_MUCL30388 99.7 100.0 Mismatch 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:171802-172677:- gene-YOL077C_MUCL39482 rna-NM_001183331.2_MUCL39482 cds-NP_014565.2_MUCL39482 99.7 100.0 Mismatch 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:187296-188171:- gene-YOL077C_MUCL42920 rna-NM_001183331.2_MUCL42920 cds-NP_014565.2_MUCL42920 99.7 100.0 Mismatch 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:185737-186612:- gene-YOL077C_NCIM3186 rna-NM_001183331.2_NCIM3186 cds-NP_014565.2_NCIM3186 99.3 100.0 Mismatch 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:178422-179297:- gene-YOL077C_NCYC1407 rna-NM_001183331.2_NCYC1407 cds-NP_014565.2_NCYC1407 99.7 100.0 Mismatch 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:161418-162293:- gene-YOL077C_PE2H3 rna-NM_001183331.2_PE2H3 cds-NP_014565.2_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:172407-173282:- gene-YOL077C_PE2H4 rna-NM_001183331.2_PE2H4 cds-NP_014565.2_PE2H4 99.7 100.0 Mismatch 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:185848-186723:- gene-YOL077C_S288C rna-NM_001183331.2_S288C cds-NP_014565.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:153728-154603:- gene-YOL077C_SA1 rna-NM_001183331.2_SA1 cds-NP_014565.2_SA1 99.6 100.0 Mismatch 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:168138-169013:- gene-YOL077C_ThermosaccDry rna-NM_001183331.2_ThermosaccDry cds-NP_014565.2_ThermosaccDry 99.8 100.0 Mismatch 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:168918-169793:- gene-YOL077C_VR1 rna-NM_001183331.2_VR1 cds-NP_014565.2_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:167801-168676:- gene-YOL077C_ZTW1 rna-NM_001183331.2_ZTW1 cds-NP_014565.2_ZTW1 99.8 100.0 Mismatch 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:171366-172241:- gene-YOL077C_Sparadoxus rna-NM_001183331.2_Sparadoxus cds-NP_014565.2_Sparadoxus 93.4 100.0 Verified 1 1 1 False True False False False

Additional files